1,2-dimethylhydrazine has been researched along with Angiogenesis, Pathologic in 8 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "procera in the rat model of colorectal cancer (CRC)." | 1.72 | Protective effect of methanol extract of latex of Calotropis procera in an experimental model of colorectal cancer. ( Das, P; Kumar, VL; Verma, S, 2022) |
| "Colon cancer is the third leading cause of cancer mortality worldwide, which results from interactions of different factors." | 1.43 | Exenatide suppresses 1,2-dimethylhydrazine-induced colon cancer in diabetic mice: Effect on tumor angiogenesis and cell proliferation. ( Mohamed, MI; Tawfik, MK, 2016) |
| "Colon cancer was induced using 1,2-dimethylhydrazine (DMH, 20 mg/kg/week, s." | 1.40 | Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation. ( Moustafa, YM; Zaafar, DK; Zaitone, SA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, VL | 2 |
| Verma, S | 2 |
| Das, P | 2 |
| Sharma, SH | 1 |
| Suresh Kumar, J | 1 |
| Madhavan, S | 1 |
| Nagarajan, S | 1 |
| Gungor, H | 1 |
| Ilhan, N | 1 |
| Eroksuz, H | 1 |
| Zaafar, DK | 1 |
| Zaitone, SA | 1 |
| Moustafa, YM | 1 |
| Tawfik, MK | 1 |
| Mohamed, MI | 1 |
| Karaca, O | 1 |
| Ertekin, T | 1 |
| Canoz, O | 1 |
| Ulger, H | 1 |
| Soysal, H | 1 |
| Kus, I | 1 |
| Banu, NA | 1 |
| Daly, RS | 1 |
| Buda, A | 1 |
| Moorghen, M | 1 |
| Baker, J | 1 |
| Pignatelli, M | 1 |
8 other studies available for 1,2-dimethylhydrazine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Protective effect of methanol extract of latex of Calotropis procera in an experimental model of colorectal cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Biomarkers, Tumor; Calotropis; Colorectal Neoplasms; DNA Fragmentati | 2022 |
Morin supplementation modulates PERK branch of UPR and mitigates 1,2-dimethylhydrazine-induced angiogenesis and oxidative stress in the colon of experimental rats.
Topics: 1,2-Dimethylhydrazine; Angiogenesis Inhibitors; Animals; Antioxidants; Colon; Disease Models, Animal | 2020 |
Chemoprevention by artesunate in a preclinical model of colorectal cancer involves down regulation of β-catenin, suppression of angiogenesis, cellular proliferation and induction of apoptosis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Apoptosis; Artemisinins; Artesunate; Aspirin; b | 2017 |
The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2 Inhibit | 2018 |
Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation.
Topics: 1,2-Dimethylhydrazine; Animals; Antigens, CD34; Antineoplastic Agents; Cell Proliferation; Colon; Co | 2014 |
Exenatide suppresses 1,2-dimethylhydrazine-induced colon cancer in diabetic mice: Effect on tumor angiogenesis and cell proliferation.
Topics: 1,2-Dimethylhydrazine; Animals; Antigens, CD34; Body Weight; Cell Proliferation; Cisplatin; Colon; C | 2016 |
Effect of endostatin on 1,2-dimethylhydrazine-induced colon tumor in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Analysis of Variance; Angiogenesis Inhibitors; Animals; Colon | 2012 |
Reduced tumour progression and angiogenesis in 1,2-dimethylhydrazine mice treated with NS-398 is associated with down-regulation of cyclooxygenase-2 and decreased beta-catenin nuclear localisation.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; beta Catenin; Bromodeoxyuridine; Carcinogens; Ce | 2011 |