1,2-dimethylhydrazine has been researched along with Adenoma in 94 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We here tested whether the secondary plant compound flavone affects the development of aberrant crypt foci and microadenomas triggered in C57BL/6J mice by 1,2-dimethylhydrazine." | 7.76 | Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice. ( Daniel, H; Diehl, D; Oesterle, D; Wenzel, U; Winkelmann, I, 2010) |
| " This study was to evaluate the preventive effects of coloclysis of NaB on 1,2-dimethylhydrazine (DMH)-induced tumorigenesis of colorectal cancer in mice." | 7.73 | [Inhibitory effect of sodium butyrate on 1,2-dimethylhydrazine-induced tumorigenesis of colorectal cancer in mice]. ( Geng, XL; Huang, LH; Li, TJ; Liu, CX; Wang, B; Zhang, SZ; Zhang, XW, 2005) |
| "CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 7.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
| "Almost equal inhibitory effects on tubular adenocarcinomas were also observed in the rats given 150 ppm JTE-522 during the postinitiation stage, suggesting that its major anticancer action is at the postinitiation phase." | 5.33 | JTE-522, a selective cyclooxygenase-2 inhibitor, inhibits induction but not growth and invasion of 1,2-dimethylhydrazine-induced tubular adenocarcinomas of colon in rats. ( Fukushima, S; Hakoi, K; Moku, M; Morimura, K; Salim, EI; Shen, J; Wanibuchi, H; Wei, M, 2005) |
| "The expression of the putative markers LGR-5 (leucine-rich-repeat-containing G-protein-coupled receptor 5), MSI-1 (Musashi-1) and DCAMKL-1 (doublecortin and calcium/calmodulin-dependent protein kinase-like-1) was studied in normal colon mucosa (NM), in the precancerous lesions Mucin Depleted Foci (MDF) and in macroscopic tumours (adenomas) of 1,2-dimethylhydrazine-treated rats." | 3.79 | Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin. ( Caderni, G; Dolara, P; Femia, AP; Salvadori, M, 2013) |
| " Groups 1, 3 and 5 were initiated by 1,2-dimethylhydrazine (DMH) 20 mg/kg body weight s." | 3.77 | Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action. ( Abou-Shafey, AE; Elgendy, SA; Masoud, AA; Salim, EI, 2011) |
| "We here tested whether the secondary plant compound flavone affects the development of aberrant crypt foci and microadenomas triggered in C57BL/6J mice by 1,2-dimethylhydrazine." | 3.76 | Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice. ( Daniel, H; Diehl, D; Oesterle, D; Wenzel, U; Winkelmann, I, 2010) |
| " Mice received intraperitoneal injections of 1,2-dimethylhydrazine (DMH) (40 mg/kg body weight) once a week for 6 weeks to selectively induce aberrant crypt foci (ACF) and tumors in the colon." | 3.75 | IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis. ( Diehl, D; Elmlinger, M; Göttlicher, M; Hessel, E; Hoeflich, A; Lahm, H; Langhammer, M; Oesterle, D; Renner-Müller, I; Wolf, E, 2009) |
| " This study was to evaluate the preventive effects of coloclysis of NaB on 1,2-dimethylhydrazine (DMH)-induced tumorigenesis of colorectal cancer in mice." | 3.73 | [Inhibitory effect of sodium butyrate on 1,2-dimethylhydrazine-induced tumorigenesis of colorectal cancer in mice]. ( Geng, XL; Huang, LH; Li, TJ; Liu, CX; Wang, B; Zhang, SZ; Zhang, XW, 2005) |
| "This study tested the effect of a new gastrin receptor antagonist, CR2945, on colorectal cancer induced by 1,2-dimethylhydrazine (DMH) in mice." | 3.70 | Inhibitory effect of a gastrin receptor antagonist, CR2945, on 1, 2-dimethylhydrazine-induced colorectal cancer in mice. ( Di Betta, E; Donato, F; Fontana, MG; Ghirardi, M; Moneghini, D; Salerni, B; Villanacci, V, 1999) |
| " In the previous study, the incidence of colonic adenoma induced with 1,2-dimethylhydrazine (DMH) in the gnotobiotic mice with Lactobacillus acidophilus, gnotobiotic mice with Escherichia coli and germ-free mice were 30, 50 and 74%, respectively." | 3.70 | Effects of intestinal bacteria on the development of colonic neoplasm II. Changes in the immunological environment. ( Abo, T; Fujimura, A; Horie, H; Kanazawa, K; Kobayashi, E; Okada, M; Yamagiwa, S, 1999) |
| " adenomas in 1,2-dimethylhydrazine (DMH)-treated CF1 mice." | 3.70 | Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice. ( Dillehay, DL; Merrill, AH; Schmelz, EM; Sullards, MC, 2000) |
| "CBA female mice, at the 17th day of pregnancy, received single intraperitoneal injection of diethylstilbestrol (DES) at the dose of 1 mg/kg body weight (b." | 3.70 | 1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol. ( Samoilov, D; Trukhanova, L; Turusov, V, 2000) |
| "CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 3.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
| "To study the effect of acetic acid colitis on 1,2-dimethylhydrazine-induced colon tumorigenesis, fischer 344 male rats, 10 weeks of age, were divided into three groups: one receiving 5% acetic acid enema (subgroup 1a); one receiving 10% acetic acid enema (subgroup 1b); and one not receiving acetic acid enema (group 2)." | 3.66 | Experimental colitis as a promoter in large-bowel tumorigenesis. ( Hagihara, PF, 1982) |
| "the third pathway of colonic carcinogenesis, remain unidentified." | 1.46 | The Histogenesis of the Third Pathway of Colonic Carcinogenesis in Rats. ( Rubio, CA, 2017) |
| "DLD-1 human colon cancer cells were utilized to investigate the effect of AGE on anti-cell proliferation." | 1.42 | Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation. ( Hirokawa, M; Jikihara, H; Nozoe, K; Qi, G; Sato, H; Shimamoto, F; Sugihara, Y, 2015) |
| " In conclusion, the data collectively show that a 50% reduction in K-ras gene dosage and RNA expression promoted experimental colorectal tumourigenesis, consistent with wild-type K-ras having a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation." | 1.40 | Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation. ( Arends, MJ; Dong, G; Hamoudi, R; Ibrahim, AE; Luo, F; Poulogiannis, G; Ye, H; Zhang, W, 2014) |
| "Almost equal inhibitory effects on tubular adenocarcinomas were also observed in the rats given 150 ppm JTE-522 during the postinitiation stage, suggesting that its major anticancer action is at the postinitiation phase." | 1.33 | JTE-522, a selective cyclooxygenase-2 inhibitor, inhibits induction but not growth and invasion of 1,2-dimethylhydrazine-induced tubular adenocarcinomas of colon in rats. ( Fukushima, S; Hakoi, K; Moku, M; Morimura, K; Salim, EI; Shen, J; Wanibuchi, H; Wei, M, 2005) |
| "Colorectal tumors were induced by means of 15 s." | 1.31 | Animal model in the study of colorectal carcinogenesis. ( Cerar, A; Glavac, D; Ravnik-Glavac, M, 2000) |
| "Colon cancer was induced by five weekly feedings of DMH." | 1.30 | Interaction of fiber and energy registration in experimental colon carcinogens. ( Klurfeld, DM; Kritchevsky, D, 1997) |
| "Colon cancer was experimentally induced in mice to examine potential effects of carcinogenesis in the colon on local mucosal immune function in situ, using the expression of type I hypersensitivity as an index of immune function." | 1.29 | Early stages of 1,2-dimethylhydrazine-induced colon carcinogenesis suppress immune-regulated ion transport of mouse distal colon. ( Broaddus, RR; Castro, GA; Wargovich, MJ, 1994) |
| "In a model of dimethylhydrazine-induced colorectal tumors in male mice aloin- or sennoside-enriched diets (0." | 1.29 | Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice. ( Baretton, G; Siegers, CP; Siemers, J, 1993) |
| "Carcinoma in situ was identified in two specimens by fluorescence, and one fluorescent specimen contained dysplasia." | 1.29 | Photo detection of carcinoma of the colon in a rat model: a pilot study. ( Clements, BM; McBrearty, FX; von Rueden, DG; Woratyla, S, 1993) |
| " The dose-response study shows a sharp increase (from 5 to 75%) of the epithelial renal tumour incidence in the range of 2, 4 and 8 injections of DMH." | 1.28 | [1,2-dimethylhydrazine induction of epithelial tumors of the kidneys in CBA strain mice]. ( Chemeris, GIu; Lanko, NS; Parfenov, IuD; Turusov, VS, 1990) |
| "Our protocols for experiment to produce colonic cancer in dog were as follows: Two beagle and 12 mongrel dogs were used." | 1.27 | [Production of experimental colonic cancer in dog. A comparative study of administrative methods of carcinogen]. ( Kishino, H, 1983) |
| "All colonic neoplasms were histologically classified either as adenomas or carcinomas with groups being allocated into tumour-free (n = 16) or tumour-bearing (n = 54), the latter group being further sub-divided into animals with adenoma alone (n = 8) and those with carcinoma (n = 46)." | 1.27 | Changes in serum lipids related to the presence of experimental colon cancer. ( Barton, TP; Cruse, JP; Lewin, MR, 1987) |
| "In DMH-induced colonic cancer, the incidence as well as the concentration was higher in male rats (60." | 1.27 | Steroid receptors in dimethylhydrazine-induced colon carcinogenesis. ( Demura, H; Demura, R; Jibiki, K; Kato, Y; Nakamura, S; Oda, S; Odagiri, E, 1985) |
| "The histogenesis of perianal squamous cell carcinomas induced by subcutaneous and intraperitoneal injection of 1,2-dimethylhydrazine dihydrochloride (DMH) and painting of methylazoxymethanol (MAM)-acetate on the anal region was investigated in 212 female BALB/c mice." | 1.26 | Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis. ( Furuya, K; Izumi, K; Kawaura, A; Kumagai, H; Otsuka, H, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (34.04) | 18.7374 |
| 1990's | 27 (28.72) | 18.2507 |
| 2000's | 22 (23.40) | 29.6817 |
| 2010's | 13 (13.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rubio, CA | 3 |
| Luo, F | 3 |
| Poulogiannis, G | 3 |
| Ye, H | 3 |
| Hamoudi, R | 3 |
| Dong, G | 3 |
| Zhang, W | 3 |
| Ibrahim, AE | 1 |
| Arends, MJ | 3 |
| Zhu, QC | 1 |
| Gao, RY | 1 |
| Wu, W | 1 |
| Guo, BM | 1 |
| Peng, JY | 1 |
| Qin, HL | 1 |
| Jikihara, H | 1 |
| Qi, G | 1 |
| Nozoe, K | 1 |
| Hirokawa, M | 1 |
| Sato, H | 1 |
| Sugihara, Y | 1 |
| Shimamoto, F | 1 |
| Sun, T | 1 |
| Liu, S | 1 |
| Zhou, Y | 1 |
| Yao, Z | 1 |
| Zhang, D | 1 |
| Cao, S | 1 |
| Wei, Z | 1 |
| Tan, B | 1 |
| Li, Y | 1 |
| Lian, Z | 1 |
| Wang, S | 1 |
| Diehl, D | 2 |
| Hessel, E | 1 |
| Oesterle, D | 2 |
| Renner-Müller, I | 1 |
| Elmlinger, M | 1 |
| Langhammer, M | 1 |
| Göttlicher, M | 1 |
| Wolf, E | 1 |
| Lahm, H | 1 |
| Hoeflich, A | 1 |
| Saini, MK | 1 |
| Sharma, P | 1 |
| Kaur, J | 1 |
| Sanyal, SN | 1 |
| Patek, CE | 1 |
| Winkelmann, I | 1 |
| Daniel, H | 1 |
| Wenzel, U | 1 |
| Banu, NA | 1 |
| Daly, RS | 1 |
| Buda, A | 1 |
| Moorghen, M | 2 |
| Baker, J | 1 |
| Pignatelli, M | 1 |
| Salim, EI | 2 |
| Abou-Shafey, AE | 1 |
| Masoud, AA | 1 |
| Elgendy, SA | 1 |
| Kissow, H | 1 |
| Hartmann, B | 1 |
| Holst, JJ | 1 |
| Viby, NE | 1 |
| Hansen, LS | 1 |
| Rosenkilde, MM | 1 |
| Hare, KJ | 1 |
| Poulsen, SS | 1 |
| Femia, AP | 2 |
| Dolara, P | 2 |
| Salvadori, M | 2 |
| Caderni, G | 2 |
| Hirose, M | 6 |
| Yamaguchi, T | 1 |
| Mizoguchi, Y | 2 |
| Akagi, K | 4 |
| Futakuchi, M | 1 |
| Shirai, T | 6 |
| Kanna, PS | 1 |
| Mahendrakumar, CB | 1 |
| Chakraborty, T | 1 |
| Hemalatha, P | 1 |
| Banerjee, P | 1 |
| Chatterjee, M | 1 |
| Hur, K | 1 |
| Kim, JR | 1 |
| Yoon, BI | 1 |
| Lee, JK | 1 |
| Choi, JH | 1 |
| Oh, GT | 1 |
| Kim, DY | 1 |
| Symolon, H | 1 |
| Schmelz, EM | 5 |
| Dillehay, DL | 4 |
| Merrill, AH | 4 |
| Vignali, F | 1 |
| Giannini, A | 1 |
| Biggeri, A | 1 |
| Gee, J | 1 |
| Przybylska, K | 1 |
| Cheynier, V | 1 |
| Wei, M | 1 |
| Morimura, K | 1 |
| Wanibuchi, H | 1 |
| Shen, J | 1 |
| Moku, M | 1 |
| Hakoi, K | 1 |
| Fukushima, S | 1 |
| Liu, CX | 1 |
| Zhang, SZ | 1 |
| Zhang, XW | 1 |
| Geng, XL | 1 |
| Li, TJ | 1 |
| Huang, LH | 1 |
| Wang, B | 1 |
| Kirley, SD | 1 |
| D'Apuzzo, M | 1 |
| Lauwers, GY | 1 |
| Graeme-Cook, F | 1 |
| Chung, DC | 1 |
| Zukerberg, LR | 1 |
| Di Pace, RF | 1 |
| Massa, S | 1 |
| Ribeiro, OG | 1 |
| Cabrera, WH | 1 |
| De Franco, M | 1 |
| Starobinas, N | 1 |
| Seman, M | 1 |
| Ibañez, OC | 1 |
| Zoghbi, S | 1 |
| Drouin, E | 1 |
| Claustre, J | 1 |
| Bara, J | 2 |
| Scoazec, JY | 1 |
| Plaisancié, P | 1 |
| Xu, H | 1 |
| Sengupta, R | 1 |
| Du, J | 1 |
| Banerjee, S | 1 |
| Sarkar, FH | 1 |
| Rishi, AK | 1 |
| Majumdar, AP | 1 |
| Hirono, I | 1 |
| Ueno, I | 1 |
| Aiso, S | 1 |
| Yamaji, T | 1 |
| Golberg, L | 1 |
| Choluj, B | 1 |
| Hladík, V | 1 |
| Vozenílek, J | 1 |
| Howarth, AE | 1 |
| Pihl, E | 1 |
| Kamiya, J | 1 |
| Saito, Y | 1 |
| Muto, T | 1 |
| Morioka, Y | 1 |
| Kishino, H | 1 |
| Jones, FE | 1 |
| Komorowski, RA | 1 |
| Condon, RE | 1 |
| Weitz, H | 1 |
| Kirscheneder, C | 1 |
| Wiebecke, B | 1 |
| Eder, M | 1 |
| Nylander, G | 1 |
| Wallin, B | 1 |
| Sveander, M | 1 |
| Alun, ML | 1 |
| Duvander, A | 1 |
| Naito, Y | 1 |
| Hattori, T | 1 |
| Helpap, B | 1 |
| Gedigk, P | 1 |
| Hagihara, PF | 1 |
| Kumagai, H | 1 |
| Kawaura, A | 2 |
| Furuya, K | 1 |
| Izumi, K | 1 |
| Otsuka, H | 1 |
| Krutovskikh, VA | 2 |
| Turusov, VS | 8 |
| Chemeris, GIu | 3 |
| Bird, RP | 2 |
| Ee, HC | 1 |
| Erler, T | 1 |
| Bhathal, PS | 1 |
| Young, GP | 1 |
| James, RJ | 1 |
| Broaddus, RR | 1 |
| Wargovich, MJ | 1 |
| Castro, GA | 1 |
| Rubio, C | 1 |
| Shetye, J | 1 |
| Hirata, K | 1 |
| Itoh, H | 1 |
| Nagata, N | 1 |
| Kuroda, Y | 1 |
| Ohsato, K | 1 |
| Webb, SK | 2 |
| Siegers, CP | 1 |
| Siemers, J | 1 |
| Baretton, G | 1 |
| Hoshiya, T | 2 |
| Takahashi, S | 2 |
| Hara, Y | 1 |
| Ito, N | 5 |
| Takahashi, A | 1 |
| Tanida, N | 1 |
| Nishikawa, M | 1 |
| Shimoyama, T | 1 |
| von Rueden, DG | 1 |
| McBrearty, FX | 1 |
| Clements, BM | 1 |
| Woratyla, S | 1 |
| Kondalenko, VF | 2 |
| Moen, CJ | 1 |
| van der Valk, MA | 1 |
| Hart, AA | 1 |
| Demant, P | 1 |
| Kimura, J | 1 |
| Ogiso, T | 1 |
| Yoshida, Y | 1 |
| Hasegawa, R | 1 |
| Kurata, M | 1 |
| Reiter, A | 1 |
| Adams, J | 1 |
| Rijnkels, JM | 2 |
| Hollanders, VM | 2 |
| Woutersen, RA | 2 |
| Koeman, JH | 2 |
| Alink, GM | 2 |
| Kritchevsky, D | 1 |
| Klurfeld, DM | 1 |
| Trukhanova, LS | 1 |
| Samoĭlov, DV | 1 |
| Ma, Q | 1 |
| Williamson, KE | 1 |
| O'rourke, D | 1 |
| Rowlands, BJ | 1 |
| Horie, H | 2 |
| Kanazawa, K | 2 |
| Okada, M | 2 |
| Narushima, S | 1 |
| Itoh, K | 1 |
| Terada, A | 1 |
| Fontana, MG | 1 |
| Donato, F | 1 |
| Villanacci, V | 1 |
| Ghirardi, M | 1 |
| Moneghini, D | 1 |
| Di Betta, E | 1 |
| Salerni, B | 1 |
| Kobayashi, E | 1 |
| Fujimura, A | 1 |
| Yamagiwa, S | 1 |
| Abo, T | 1 |
| Sullards, MC | 1 |
| Turusov, V | 1 |
| Trukhanova, L | 1 |
| Samoilov, D | 1 |
| Ravnik-Glavac, M | 1 |
| Cerar, A | 1 |
| Glavac, D | 1 |
| Schleiffer, R | 1 |
| Duranton, B | 1 |
| Gossé, F | 1 |
| Hasselmann, M | 1 |
| Raul, F | 1 |
| Nakamura, A | 1 |
| Hagiwara, A | 2 |
| Miyashita, K | 1 |
| Nakanishi, T | 1 |
| Sano, M | 1 |
| Tamano, S | 2 |
| Kadota, T | 1 |
| Koda, T | 2 |
| Nakamura, M | 2 |
| Imaida, K | 2 |
| Zhaorigetu, S | 1 |
| Sasaki, M | 1 |
| Watanabe, H | 1 |
| Kato, N | 1 |
| Yoshino, H | 1 |
| Ichihara, T | 1 |
| Kawabe, M | 1 |
| Aoki, H | 1 |
| Philipp-Staheli, J | 1 |
| Kim, KH | 1 |
| Payne, SR | 1 |
| Gurley, KE | 1 |
| Liggitt, D | 1 |
| Longton, G | 1 |
| Kemp, CJ | 1 |
| Gunning, WT | 1 |
| Castonguay, A | 1 |
| Goldblatt, PJ | 1 |
| Stoner, GD | 1 |
| Masuda, A | 1 |
| Kamano, K | 1 |
| Okuyama, H | 1 |
| Lanko, NS | 1 |
| Parfenov, IuD | 1 |
| Rowlatt, C | 1 |
| Cruse, JP | 2 |
| Barton, T | 1 |
| Sadrudin, AA | 1 |
| Lewin, MR | 2 |
| Daniel, FB | 1 |
| DeAngelo, AB | 1 |
| Stober, JA | 1 |
| Pereira, MA | 1 |
| Olson, GR | 1 |
| Kolár, Z | 2 |
| Deschner, EE | 1 |
| Ince, P | 1 |
| Finney, KJ | 1 |
| Sunter, JP | 1 |
| Appleton, DR | 1 |
| Watson, AJ | 1 |
| Daher, N | 1 |
| Gautier, R | 1 |
| Abourachid, H | 1 |
| Decaens, C | 1 |
| Ljubimov, AV | 1 |
| Reddy, BS | 1 |
| Tanaka, T | 1 |
| Temple, NJ | 1 |
| Basu, TK | 1 |
| Barton, TP | 1 |
| Kingsnorth, AN | 1 |
| Abu-Khalaf, M | 1 |
| Ross, JS | 1 |
| Malt, RA | 1 |
| Ikawa, E | 1 |
| Thamavit, W | 1 |
| Chemeris, GY | 1 |
| Parfenov, YD | 1 |
| Kennedy, MF | 1 |
| Tutton, PJ | 1 |
| Barkla, DH | 1 |
| Odagiri, E | 1 |
| Jibiki, K | 1 |
| Kato, Y | 1 |
| Nakamura, S | 1 |
| Oda, S | 1 |
| Demura, R | 1 |
| Demura, H | 1 |
| Ahnen, DJ | 1 |
| Sumiyoshi, H | 1 |
| Dufek, V | 1 |
| Krepela, E | 1 |
| Vicar, J | 1 |
| Král, V | 1 |
2 reviews available for 1,2-dimethylhydrazine and Adenoma
| Article | Year |
|---|---|
Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Cholic Acid; Cho | 1995 |
Animal models of carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethy | 1988 |
92 other studies available for 1,2-dimethylhydrazine and Adenoma
| Article | Year |
|---|---|
The Histogenesis of the Third Pathway of Colonic Carcinogenesis in Rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogenesis; Carcinoma; Carcinoma, Signet Ring Cell; Cel | 2017 |
Updated Histologic Classification of Adenomas and Carcinomas in the Colon of Carcinogen-treated Sprague-Dawley Rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Disease Models, Anim | 2017 |
Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation.
Topics: 1,2-Dimethylhydrazine; Adenoma; Alleles; Animals; Apoptosis; Cell Proliferation; Colorectal Neoplasm | 2014 |
Effect of a high-fat diet in development of colonic adenoma in an animal model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Adiposity; Animals; Biomarkers, Tumor; Cell Cycle; Cell Proliferatio | 2014 |
Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Blotting, Western; | 2015 |
Evolutionary biologic changes of gut microbiota in an 'adenoma-carcinoma sequence' mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli Protein; Animals; Bacteri | 2017 |
IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Cell Proliferation; Cells, Cultur | 2009 |
The cyclooxygenase-2 inhibitor etoricoxib is a potent chemopreventive agent of colon carcinogenesis in the rat model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Biomarkers; Colonic Neo | 2009 |
K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transforma | 2010 |
Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Adenoma; Animals; Antineoplastic Agents, Phytogenic; Apo | 2010 |
Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; beta Catenin; Carcinogens; Cell Proliferation; C | 2011 |
Reduced tumour progression and angiogenesis in 1,2-dimethylhydrazine mice treated with NS-398 is associated with down-regulation of cyclooxygenase-2 and decreased beta-catenin nuclear localisation.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; beta Catenin; Bromodeoxyuridine; Carcinogens; Ce | 2011 |
Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; | 2011 |
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Adenoma; Anatomy, Cross-Sectional; Animals; Chlorocebus | 2012 |
Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; beta Catenin; Biomarkers, Tumor; Celecoxib; Cell Nucleus; C | 2013 |
Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogenicity Tests | 2002 |
Effect of vanadium on colonic aberrant crypt foci induced in rats by 1,2 dimethyl hydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma; Colon; Colonic Neoplasms; Cytochrom | 2003 |
Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Cycle; Colon; Colonic Neo | 2000 |
Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Diet; | 2004 |
Effect of polyphenolic extracts from red wine and 4-OH-coumaric acid on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Antioxidants; Carcinogens; Colonic Neoplasms; Colorectal Ne | 2005 |
JTE-522, a selective cyclooxygenase-2 inhibitor, inhibits induction but not growth and invasion of 1,2-dimethylhydrazine-induced tubular adenocarcinomas of colon in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Benzenesulfonates; Biomarkers, Tumor; Carci | 2005 |
[Inhibitory effect of sodium butyrate on 1,2-dimethylhydrazine-induced tumorigenesis of colorectal cancer in mice].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Butyrates; Colorectal Neoplasms; Dose-Respo | 2005 |
The Cables gene on chromosome 18Q regulates colon cancer progression in vivo.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Carrier Proteins; Chromosome D | 2005 |
Inverse genetic predisposition to colon versus lung carcinogenesis in mouse lines selected based on acute inflammatory responsiveness.
Topics: 1,2-Dimethylhydrazine; Acute Disease; Adenocarcinoma; Adenoma; Animals; Antiviral Agents; Carcinogen | 2006 |
Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; beta Catenin; Carcinogens; Carcinoma; Cell Line, Tumor; Col | 2007 |
Regression of early and intermediate stages of colon cancer by targeting multiple members of the EGFR family with EGFR-related protein.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Colonic Neop | 2007 |
Enhancing effect of dextran sulfate sodium on colorectal carcinogenesis by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Cocarcinogenesis; | 1983 |
[An experimental model of cancer of the large intestine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Cholestyramine Resin; Colonic | 1984 |
High-fat diet promotes and causes distal shift of experimental rat colonic cancer--beer and alcohol do not.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Alcohol Drinking; Animals; Beer; Carcinogens; Coloni | 1984 |
[Strain differences in susceptibility of rat colon to 1,2-dimethyl-hydrazine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Meth | 1983 |
[Production of experimental colonic cancer in dog. A comparative study of administrative methods of carcinogen].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dogs; F | 1983 |
The effects of ascorbic acid and butylated hydroxyanisole in the chemoprevention of 1,2-dimethylhydrazine-induced large bowel neoplasms.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Anisoles; Ascorbic Ac | 1984 |
The effect of cholecystectomy on the induction of colorectal tumors in mice by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma; Cholecystectomy; Colonic Neoplasms; | 1984 |
Carcinogenesis at colonic anastomotic sites. An animal study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazine | 1984 |
Studies on experimental colon tumorigenesis in rats. 1. Strain differences in incidence, location and tumor types of 1, 2-dimethylhydrazine-induced tumors.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Female; | 1981 |
Development and cell kinetics of colonic tumors induced in mice by dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Autoradiography; Carcinoma; Cell Division; | 1983 |
Experimental colitis as a promoter in large-bowel tumorigenesis.
Topics: 1,2-Dimethylhydrazine; Acetates; Adenocarcinoma; Adenoma; Animals; Colitis; Colonic Neoplasms; Dimet | 1982 |
Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Azo Compounds; Carcinogens; Carcinoma, Squa | 1982 |
[Morphogenesis of experimental cancer of the large intestine (according to the results of scanning electron and light microscopy)].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhyd | 1982 |
[Effect of castration and mouse strain on 1, 2-dimethylhydrazine induction of pararenal angiosarcomas and kidney adenomas].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Castration; Dimethylhydrazines; Hemangiosarcoma; Kidney Neo | 1982 |
Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; CDX2 Transcription Factor; Colon; Colonic Neopla | 1995 |
Early stages of 1,2-dimethylhydrazine-induced colon carcinogenesis suppress immune-regulated ion transport of mouse distal colon.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Antigens, Helminth; Child; Colon; Colonic Neoplasms; Dimeth | 1994 |
Flat adenoma-adenocarcinoma sequence in the colon of rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhyd | 1994 |
Experimental carcinogenesis in the rat intestine induced by two different carcinogens--evaluation of carcinogenic action and its effect on ornithine decarboxylase activity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Dimethylhyd | 1994 |
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Carcinogens; Cell Div | 1994 |
Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aloe; Animals; Anthraquinones; Carcinogens; Carcinoma; Cathartics; C | 1993 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitr | 1993 |
Sulphated bile acid per se inhibits colonic carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Administration, Rectal; Animal | 1993 |
Photo detection of carcinoma of the colon in a rat model: a pilot study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma in Situ; Colonic Neo | 1993 |
[Ultrastructure of renal-cell tumors induced in mice by 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Renal Cell; Dime | 1995 |
Different genetic susceptibility to aberrant crypts and colon adenomas in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Crosses, | 1996 |
Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carc | 1996 |
Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Fema | 1996 |
Renal cell tumours in mice: electron microscopy versus immunohistochemistry.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Biomarkers, Tumor; Dimethylhydrazines; gamma-Glutamyltransf | 1997 |
Interaction of dietary fat with a vegetables-fruit mixture on 1,2-dimethylhydrazine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogens; Colorectal Neopla | 1997 |
Interaction of fiber and energy registration in experimental colon carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dietary Fiber; Dimethylhydr | 1997 |
Interaction of dietary fat and of a vegetables/fruit mixture on 1,2-dimethylhydrazine- or N-methyl-N'-nitro-N-nitrosoguanidine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colorectal Neoplasms; Dietary | 1997 |
[Effect of prenatal treatment with diethylstilbestrol on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA mice].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Diethylstilbestrol; Kidney | 1998 |
The effects of l-arginine on crypt cell hyperproliferation in colorectal cancer.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Arginine; Carcinogens; Cell Division; Colon | 1999 |
Effects of intestinal bacteria on the development of colonic neoplasm: an experimental study.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Bacteria; Bile Acids and Salts; Carcinogens; Colonic Neopla | 1999 |
Inhibitory effect of a gastrin receptor antagonist, CR2945, on 1, 2-dimethylhydrazine-induced colorectal cancer in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Benzodiazepines; Carcinogens; Colorectal Ne | 1999 |
Effects of intestinal bacteria on the development of colonic neoplasm II. Changes in the immunological environment.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; CD3 Complex; Colonic Neoplasms; Escherichia co | 1999 |
Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Apoptosis; Carcinogens; Colonic Neoplasms; | 2000 |
1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Diethylstilbestrol; Female; I | 2000 |
Animal model in the study of colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Colorectal Neoplasm | 2000 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
Green tea catechins enhance tumor development in the colon without effects in the lung or thyroid after pretreatment with 1,2-Dimethylhydrazine or 2,2'-dihydroxy-di-n-propylnitrosamine in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Catechin; Colonic Neop | 2001 |
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Administration, Oral; Anim | 2001 |
Supplemental silk protein, sericin, suppresses colon tumorigenesis in 1,2-dimethylhydrazine-treated mice by reducing oxidative stress and cell proliferation.
Topics: 1,2-Dimethylhydrazine; 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Adenoma; Aldehydes; Animals; Apo | 2001 |
Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Administration, Oral; Animals; Anthocyanins; Anticarcinogenic Agents | 2002 |
Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli Protein; Animals; beta Ca | 2002 |
Renal cell tumors induced in CBA male mice by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma, Renal Cell; Dimethylhydrazines; gam | 1992 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; alph | 1990 |
[1,2-dimethylhydrazine induction of epithelial tumors of the kidneys in CBA strain mice].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma; Cystadenocarcinoma; Dimethylhydrazi | 1990 |
Comparison of the significance of three histopathological thresholds of malignancy in experimental colorectal tumours.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma in Situ; Colonic Neoplasms; Dimethyl | 1989 |
Chloroform inhibition of 1,2-dimethylhydrazine-induced gastrointestinal tract tumors in the Fisher 344 rat.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Chloroform; Dimethylhydrazines; Gastrointestin | 1989 |
Changes in the tissue-specific antimitotic effect of mice serum during 1,2-dimethylhydrazine induced cancerogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Chick Embryo; Colonic Neoplasms; Dimethylhydra | 1986 |
A protective effect of sulindac against chemically-induced primary colonic tumours in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhyd | 1988 |
Rat colonic carcinogenesis after ureterosigmoidostomy: pathogenesis and immunohistological study.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Antigens, Neoplasm; Colon, Sigmoid; Colonic | 1988 |
Distribution of laminin and collagen type IV in rat colon tumors induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Basement Membrane; Carcinoma in Situ; Collagen; Colon; Colo | 1987 |
Interactions of selenium deficiency, vitamin E, polyunsaturated fat, and saturated fat on azoxymethane-induced colon carcinogenesis in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Dietary Fa | 1986 |
Selenium and cabbage and colon carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Brassica; Colonic Neoplasms; D | 1987 |
Changes in serum lipids related to the presence of experimental colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenoma; Alanine Transaminase; Alkaline Phosphatase; Animals; Carcinoma; Chol | 1987 |
Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Body Weight; Carcinoma, Squamous Cell; Dime | 1985 |
Modification by five antioxidants of 1,2-dimethylhydrazine-initiated colon carcinogenesis in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Buty | 1985 |
Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Androgens; Animals; Carcinogens; Castration; Colonic Neoplasms; Dime | 1985 |
Adrenergic factors regulating cell division in the colonic crypt epithelium during carcinogenesis and in colonic adenoma and adenocarcinoma.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Cell Division; Cell Transformation, Neoplas | 1985 |
Steroid receptors in dimethylhydrazine-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Colon; Colonic Neoplasms; Dimethylhydrazine | 1985 |
Are animal models of colon cancer relevant to human disease.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Colonoscopy; Dimethylhydrazin | 1985 |
Effects of vitamin E deficiency on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Dimethylhydrazines; Intestinal | 1985 |
Changes in tissue and serum activity of cathepsin B-like cysteine proteinase during colorectal carcinogenesis by 1,2-dimethylhydrazine in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Cathepsin B; Cathepsins; Colonic Neoplasms; Dimethylhydrazi | 1985 |