Compounds > 1,2-dimethylhydrazine
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1,2-dimethylhydrazine and Acute Liver Injury, Drug-Induced

1,2-dimethylhydrazine has been researched along with Acute Liver Injury, Drug-Induced in 5 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Research Excerpts

ExcerptRelevanceReference
"Bowl or colorectal cancer (CRC) is the third most common type of cancer with about two million new cases every year."1.72The Antitumor Activity of Ginger against Colorectal Cancer Induced by Dimethylhydrazine in Rats. ( Abdel-Rasol, MA; El-Beih, NM; El-Sayed, WM; Yahya, SS, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Abdel-Rasol, MA1
El-Beih, NM1
Yahya, SS1
El-Sayed, WM1
Pandey, S1
Singh, A1
Kumar, P1
Chaudhari, A1
Nareshkumar, G1
REINHARDT, CF2
PINKERTON, MK1
DINMAN, BD1
Devasena, T1
Venugopal Menon, P1

Other Studies

5 other studies available for 1,2-dimethylhydrazine and Acute Liver Injury, Drug-Induced

ArticleYear
The Antitumor Activity of Ginger against Colorectal Cancer Induced by Dimethylhydrazine in Rats.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:8

    Topics: 1,2-Dimethylhydrazine; Animals; Chemical and Drug Induced Liver Injury; Cisplatin; Colonic Neoplasms

2022
Probiotic Escherichia coli CFR 16 producing pyrroloquinoline quinone (PQQ) ameliorates 1,2-dimethylhydrazine-induced oxidative damage in colon and liver of rats.
    Applied biochemistry and biotechnology, 2014, Volume: 173, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogens; Catalase; Chemical and Drug Induced Liver

2014
ACUTE HEPATOTOXICITY AND ENZYMATIC RESPONSE TO HYDRAZINE AND 1,1-DIMETHYLHYDRAZINE IN RATS. AMRL-TR-65-19.
    AMRL-TR. Aerospace Medical Research Laboratories (U.S.), 1965

    Topics: 1,2-Dimethylhydrazine; Blood; Chemical and Drug Induced Liver Injury; Dimethylhydrazines; Hepatitis;

1965
TOXICITY OF HYDRAZINE AND 1,1-DIMETHYLHYDRAZINE (UDMH): HEPATOSTRUCTURAL AND ENZYMATIC CHANGE.
    Archives of environmental health, 1965, Volume: 10

    Topics: 1,2-Dimethylhydrazine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clini

1965
Fenugreek seeds modulate 1,2-dimethylhydrazine-induced hepatic oxidative stress during colon carcinogenesis.
    The Italian journal of biochemistry, 2007, Volume: 56, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Catalase; Chemical and Drug I

2007