1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Sciatica

1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt has been researched along with Sciatica in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	51 (78.46)	18.7374
1990's	10 (15.38)	18.2507
2000's	4 (6.15)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hoogland, T; Miklitz, B; Ramirez, A; Schubert, M	1
Gibson, JN; Waddell, G	1
Benoist, M; Busson, J; Cauchoix, J; Deburge, A; Heripret, G; Rigot, J	1
Cecile, JP; Deschamps, C; Makart, A	1
Benoist, M; Busson, J; Deburge, A	1
Fager, CA	1
Fisher, RG	1
Murray, J	1
Boyd, RJ; Burton, C; Ford, LT; Hejna, WJ; Javid, MJ; Millett, DK; Newton, SE; Nordby, EJ; Thisted, R; Whisler, WW; Widell, EH; Wiltse, LL	1
Waddell, G	1
Benoist, M; Bouillet, R; Mulholland, R	1
Connolly, JF	1
Cecile, JP; Cipel, L; Debroucker, R; Descamps, C; Desmarchelier, F; Dufour, R; Foucart, H; Vincent, G	1
Deutman, R; Konings, JG; Williams, FJ	1
Chastanet, P; Cocheteux, P; Delcambre, B; Delfosse, JM	1
Warner, KE	1
Benoist, M; Deburge, A; Heripret, G	1
McCulloch, JA	1
Benoist, M; Busson, J; Cauchoix, J; Deburge, A; Heripret, G; Nedjar, C	1
Konings, JG	1
Fraser, RD; Javid, MJ; Nordby, EJ	1
Brugman, E; Deldycke, H; Deryckere, P; Friberg, J; Gheysen, F; Goubau, J; Herpels, V; Louwaege, A	1
Follett, KA; Maves, TJ; Moore, SA; Rich, G; Sawin, PD; Smith, BA; Traynelis, VC	1
Burton, AK; Cleary, J; Tillotson, KM	1
Bourgeois, P; Le Goff, P	1
Daughety, JS; Herrick, RB; Hoover, BB	1
Graham, CE	2
Dubuc, F; Rouleau, C	1
Deutman, R	1
Anger, C; Betheuil, V; Cotty, P; Fouquet, B; Goupille, P; Valat, JP	1
Auque, J; Gendrault, P; Hepner, H; Marchal, JC	1
Buttle, DJ; Charles, A; Dando, PM; Jenner, JR	1
Javid, MJ	1
Bouillet, R	2
Austin, RT; Zuk, JA	1
Nordby, EJ	2
Benoist, M	1
Nachemson, AL	1
Ortiz, JE; Rojas, JE	2
Amor, B; Chevrot, A; Feldman, J; Godefroy, D; Horreard, P; Menkès, CJ; Pallardy, G; Zenny, JC	1
Amor, B; Chevrot, A; Cormier, C; Menkès, CJ	1
Belmatoug, N; Benoist, M; Binoche, T; Bourgeois, P; Busson, G; Folinais, D; Frot, B; Lassale, P; Montagner, C; Palazzo, E	1
Maslanka, T; Sideranko, C	1
Nachemson, A	1
Dabezies, EJ; Langford, K; Morris, J; Shields, CB; Wilkinson, HA	1
Alexander, AH; Burkus, JK; Mitchell, JB	1
Nachemson, AL; Rydevik, B	1
Grubb, A	1
LeBlanc, FE	1
Hoogmartens, M	1
Bochu, M; Megard, M; Vignon, E	1
Buttle, DJ; Dixon, AK; Jenner, JR	1
Loew, F	1
Chung, BU; Flanagan, MN	1
Buckley, J; Gibson, MJ; Mulholland, RC; Worthington, BS	1
Abrahamson, M; Barrett, AJ; Buttle, DJ	1
Bonafe, A; Lagarrigue, J; Lazorthes, Y; Richaud, J; Roger, B; Verdie, JC	1
Farine, I; Ganel, A; Horoszowski, H; Israeli, A	1
Abla, A; Maroon, JC	1
Haney, PL; Mootz, RD	1

Reviews

10 review(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Sciatica

Article	Year
Surgical interventions for lumbar disc prolapse: updated Cochrane Review. Spine, 2007, Jul-15, Volume: 32, Issue:16 Topics: Chymopapain; Cicatrix; Diskectomy; Dura Mater; Endoscopy; Gels; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laser Therapy; Lumbar Vertebrae; Neurosurgical Procedures; Postoperative Complications; Randomized Controlled Trials as Topic; Sciatica; Treatment Outcome	2007
[Chemonucleolysis in the treatment of sciatica caused by herniated disk]. Presse medicale (Paris, France : 1983), 1984, Mar-24, Volume: 13, Issue:12 Topics: Anaphylaxis; Animals; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Radiography; Sciatica	1984
Chymopapain chemonucleolysis. Acta orthopaedica Scandinavica. Supplementum, 1993, Volume: 251 Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Sciatica	1993
Chemonucleolysis. Spine, 1996, May-01, Volume: 21, Issue:9 Topics: Adult; Aged; Chymopapain; Contraindications; Cost-Benefit Analysis; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Middle Aged; Sciatica; Treatment Outcome; United States	1996
Should we accept to stop using chymopapain nucleolysis? Joint bone spine, 2002, Volume: 69, Issue:3 Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Sciatica	2002
The case for chemonucleolysis in discogenic sciatica. A review. Acta orthopaedica Scandinavica, 1992, Volume: 63, Issue:5 Topics: Animals; Chymopapain; Evaluation Studies as Topic; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Sciatica; Treatment Outcome	1992
Advances in low-back pain. Clinical orthopaedics and related research, 1985, Issue:200 Topics: Animals; Back Pain; Biomechanical Phenomena; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Movement; Pressure; Rest; Sciatica; Spinal Diseases; Spondylolisthesis; Traction	1985
Recent advances in the treatment of low back pain. International orthopaedics, 1985, Volume: 9, Issue:1 Topics: Animals; Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Movement; Physical Exertion; Posture; Pressure; Sciatica; Stress, Mechanical; Stress, Psychological; Traction	1985
Chemonucleolysis for sciatica. A critical review. Acta orthopaedica Scandinavica, 1988, Volume: 59, Issue:1 Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Sciatica	1988
Safer proteinase treatment of sciatica. A biochemical preview of chymopapain inhibitors. Acta orthopaedica Scandinavica, 1988, Volume: 59, Issue:1 Topics: Chymopapain; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Intervertebral Disc Displacement; Protease Inhibitors; Sciatica	1988

Trials

10 trial(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Sciatica

Article	Year
Transforaminal posterolateral endoscopic discectomy with or without the combination of a low-dose chymopapain: a prospective randomized study in 280 consecutive cases. Spine, 2006, Nov-15, Volume: 31, Issue:24 Topics: Adult; Chymopapain; Combined Modality Therapy; Decompression, Surgical; Diskectomy; Endoscopy; Female; Follow-Up Studies; Humans; Injections, Intralesional; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Minimally Invasive Surgical Procedures; Patient Satisfaction; Postoperative Complications; Prospective Studies; Recovery of Function; Recurrence; Sciatica; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome	2006
Safety and efficacy of chymopapain (Chymodiactin) in herniated nucleus pulposus with sciatica. Results of a randomized, double-blind study. JAMA, 1983, May-13, Volume: 249, Issue:18 Topics: Adult; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Random Allocation; Sciatica; Sex Factors	1983
Chemonucleolysis for relief of sciatica due to a herniated intervertebral disc. Canadian Medical Association journal, 1981, Apr-01, Volume: 124, Issue:7 Topics: Adult; Chymopapain; Clinical Trials as Topic; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Ontario; Random Allocation; Sciatica	1981
Single-blind randomised controlled trial of chemonucleolysis and manipulation in the treatment of symptomatic lumbar disc herniation. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2000, Volume: 9, Issue:3 Topics: Adolescent; Adult; Chymopapain; Costs and Cost Analysis; Disability Evaluation; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Manipulation, Spinal; Middle Aged; Prospective Studies; Sciatica; Single-Blind Method; Surveys and Questionnaires; Treatment Outcome	2000
Chemonucleolysis: a double blind study comparing chemonucleolysis with intra discal hydrocortisone: in the treatment of backache and sciatica. Clinical orthopaedics and related research, 1976, Issue:117 Topics: Adult; Anaphylaxis; Back Pain; Chymopapain; Clinical Trials as Topic; Endopeptidases; Female; Humans; Hydrocortisone; Injections; Male; Middle Aged; Sciatica	1976
Low-dose, low-volume chemonucleolysis. A biochemical study. Spine, 1992, Volume: 17, Issue:1 Topics: Adult; Chymopapain; Female; Glycosaminoglycans; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Prospective Studies; Sciatica	1992
[Double-blind study of the treatment of disc lumbosciatica by chemonucleolysis]. Revue du rhumatisme et des maladies osteo-articulaires, 1986, Volume: 53, Issue:3 Topics: Adult; Aged; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Sciatica; Time Factors	1986
[Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months]. Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:10 Topics: Adult; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Injections, Spinal; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation; Sciatica; Triamcinolone Acetonide	1988
Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study. Spine, 1988, Volume: 13, Issue:5 Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Double-Blind Method; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Middle Aged; Muscular Diseases; Random Allocation; Sciatica; Spasm; Spine	1988
Sciatica--management by chemonucleolysis versus surgical discectomy. Neurosurgical review, 1986, Volume: 9, Issue:1-2 Topics: Chymopapain; Clinical Trials as Topic; Double-Blind Method; Humans; Injections; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Random Allocation; Sciatica	1986

Other Studies

45 other study(ies) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Sciatica

Article	Year
[Treatment of disk sciatica by chemonucleolysis. 120 cases]. Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1982, Volume: 68, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica	1982
[Chemonucleolysis]. Journal belge de radiologie, 1982, Volume: 65, Issue:5 Topics: Anesthesia, Local; Back Pain; Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc; Sciatica	1982
The age-old back problem. New fad, same fallacies. Spine, 1984, Volume: 9, Issue:3 Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Laminectomy; Prognosis; Sciatica; Spinal Fusion	1984
Injection therapy for herniated disks. Background and usefulness. Postgraduate medicine, 1984, Volume: 75, Issue:8 Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Laminectomy; Microbial Collagenase; Sciatica; Tomography, X-Ray Computed	1984
[Chemonucleolysis valid alternative to lumbar discoidectomy]. L'union medicale du Canada, 1983, Volume: 112, Issue:1 Topics: Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Radiography; Sciatica	1983
Technique of chemonucleolysis. Acta orthopaedica Belgica, 1983, Volume: 49 Suppl 1 Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Sciatica	1983
Chemonucleolysis. Results of a European survey. Acta orthopaedica Belgica, 1983, Volume: 49 Suppl 1 Topics: Chymopapain; Endopeptidases; Europe; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Sciatica	1983
Preliminary experiences with chemonucleolysis at the University of Nebraska Medical Center. The Nebraska medical journal, 1984, Volume: 69, Issue:1 Topics: Chymopapain; Double-Blind Method; Endopeptidases; Female; Humans; Injections, Spinal; Male; Sciatica	1984
[Results of discolysis with chymopapain. 300 cases]. Annales de radiologie, 1983, Volume: 26, Issue:8 Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Radiography; Sciatica	1983
The effects of chemonucleolysis as demonstrated by computerised tomography. The Journal of bone and joint surgery. British volume, 1984, Volume: 66, Issue:3 Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbosacral Region; Male; Middle Aged; Myelography; Prospective Studies; Sciatica; Time Factors; Tomography, X-Ray Computed	1984
[Discal nucleolysis in the treatment of common sciatica]. LARC medical, 1984, Volume: 4, Issue:9 Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica	1984
Chemonucleolysis with chymopapain. Hospital practice (Office ed.), 1984, Volume: 19, Issue:2 Topics: Anaphylaxis; Anesthesia, General; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Sciatica	1984
Indications and contra-indications of nucleolysis. Acta orthopaedica Belgica, 1983, Volume: 49 Suppl 1 Topics: Cauda Equina; Chymopapain; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Nerve Compression Syndromes; Pregnancy; Sciatica	1983
[Treatment of intervertebral disk sciatica by chemonucleolysis. Analysis of 56 cases]. Revue du rhumatisme et des maladies osteo-articulaires, 1981, Volume: 48, Issue:11 Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica	1981
Efficiency of discography followed by chemonucleolysis in the treatment of sciatica. Journal belge de radiologie, 1996, Volume: 79, Issue:2 Topics: Adolescent; Adult; Aged; Chymopapain; Contrast Media; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Iohexol; Male; Middle Aged; Radiography; Sciatica	1996
Chymopapain-induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica. Journal of neurosurgery, 1997, Volume: 86, Issue:6 Topics: Acute Disease; Animals; Behavior, Animal; Chymopapain; Inflammation Mediators; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred F344; Sciatic Nerve; Sciatica	1997
Editorial: Chemonucleolysis. Lancet (London, England), 1975, May-03, Volume: 1, Issue:7914 Topics: Chymopapain; Endopeptidases; Evaluation Studies as Topic; Humans; Injections, Intra-Articular; Intervertebral Disc; Radiographic Magnification; Sciatica	1975
Clinical and electromyographic evaluation after chemonucleolysis for lumbar disk disease. Southern medical journal, 1975, Volume: 68, Issue:12 Topics: Back Pain; Chymopapain; Electromyography; Endopeptidases; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Sciatica	1975
[Lumbo-sciatica and chemonucleolysis]. L'union medicale du Canada, 1977, Volume: 106, Issue:1 Topics: Chymopapain; Dexamethasone; Endopeptidases; Humans; Intervertebral Disc Displacement; Sciatica	1977
[Long-term results of chymopapain chemonucleolysis]. Revue du rhumatisme et des maladies osteo-articulaires, 1992, Volume: 59, Issue:12 Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Retrospective Studies; Sciatica	1992
[Surgery for lumbar disk hernia after chemonucleolysis. Results and analysis. Apropos of 100 cases]. Chirurgie; memoires de l'Academie de chirurgie, 1992, Volume: 118, Issue:10 Topics: Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Male; Reoperation; Sciatica; Treatment Failure	1992
A 1- to 4-year follow-up review of treatment of sciatica using chemonucleolysis or laminectomy. Journal of neurosurgery, 1992, Volume: 76, Issue:2 Topics: Adult; Back Injuries; Chymopapain; Employment; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Laminectomy; Male; Middle Aged; Reoperation; Sciatica; Spasm; Tomography, X-Ray Computed; Treatment Outcome	1992
Treatment of sciatica. A comparative survey of complications of surgical treatment and nucleolysis with chymopapain. Clinical orthopaedics and related research, 1990, Issue:251 Topics: Adolescent; Adult; Back Pain; Chymopapain; Discitis; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Peripheral Nervous System Diseases; Postoperative Complications; Pulmonary Embolism; Sciatica; Thrombophlebitis	1990
Epidural adhesions after chymopapain chemonucleolysis. Journal of the Royal College of Surgeons of Edinburgh, 1989, Volume: 34, Issue:1 Topics: Adult; Aged; Chymopapain; Epidural Space; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica; Spinal Canal; Tissue Adhesions	1989
Chemonucleolysis for sciatica. Acta orthopaedica Scandinavica, 1989, Volume: 60, Issue:2 Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Sciatica	1989
[Nucleolysis]. Soins. Chirurgie (Paris, France : 1982), 1988, Issue:86 Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Microbial Collagenase; Sciatica	1988
Low back pain, sciatica and chemonucleolysis: a community hospital experience. The Journal of the Florida Medical Association, 1986, Volume: 73, Issue:3 Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica	1986
[Long-term results of chymopapain nucleolysis]. Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:2 Topics: Adult; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Recurrence; Retrospective Studies; Sciatica	1988
[Sciatica and chemonucleolysis]. Boletin de la Asociacion Medica de Puerto Rico, 1985, Volume: 77, Issue:6 Topics: Aftercare; Chymopapain; Cimetidine; Diphenhydramine; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement; Methods; Premedication; Sciatica; Spasm	1985
Chemonucleolysis for sciatica and low back pain. The Medical journal of Australia, 1985, Apr-15, Volume: 142, Issue:8 Topics: Anaphylaxis; Back Pain; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Postoperative Care; Sciatica	1985
An alternative to back surgery--for some patients. RN, 1985, Volume: 48, Issue:5 Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Male; Postoperative Care; Sciatica	1985
Evaluation and treatment of chemonucleolysis failures. Orthopedics, 1988, Volume: 11, Issue:12 Topics: Adult; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Pain; Sciatica	1988
[Complication of disk nucleolysis with chymopapain]. Acta orthopaedica Belgica, 1987, Volume: 53, Issue:2 Topics: Adult; Chymopapain; Drug Hypersensitivity; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Male; Middle Aged; Nervous System Diseases; Sciatica; Spinal Diseases; Surveys and Questionnaires	1987
Incidental myelogram during lateral discography. Report of two cases. Acta orthopaedica Belgica, 1987, Volume: 53, Issue:2 Topics: Chymopapain; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Intervertebral Disc Chemolysis; Myelography; Sciatica	1987
[Treatment of disk sciatica by chemonucleolysis. Apropos of 166 cases]. Neuro-Chirurgie, 1986, Volume: 32, Issue:1 Topics: Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica	1986
Mechanism of action of intradiscal chymopapain in the treatment of sciatica: a clinical, biochemical, and radiological study. Annals of the rheumatic diseases, 1986, Volume: 45, Issue:6 Topics: Adolescent; Adult; Aged; Chymopapain; Female; Glycosaminoglycans; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica; Tomography, X-Ray Computed	1986
Different operative possibilities for treatment of lumbar disc herniations--how to choose the best method for the individual patient. Neurosurgical review, 1986, Volume: 9, Issue:1-2 Topics: Chymopapain; Humans; Injections; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Microsurgery; Postoperative Complications; Prognosis; Sciatica; Spinal Stenosis	1986
Roentgenographic changes in 188 patients 10-20 years after discography and chemonucleolysis. Spine, 1986, Volume: 11, Issue:5 Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Radiography; Sciatica; Time Factors	1986
The changes in the intervertebral disc after chemonucleolysis demonstrated by magnetic resonance imaging. The Journal of bone and joint surgery. British volume, 1986, Volume: 68, Issue:5 Topics: Acute Disease; Adolescent; Adult; Chymopapain; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Magnetic Resonance Spectroscopy; Male; Prospective Studies; Sciatica; Time Factors	1986
The biochemistry of the action of chymopapain in relief of sciatica. Spine, 1986, Volume: 11, Issue:7 Topics: Cartilage; Chromatography, Ion Exchange; Chymopapain; Cysteine; Glycosaminoglycans; Humans; Hydrogen-Ion Concentration; Intervertebral Disc Displacement; Proteoglycans; Sciatica	1986
[Chemonucleolysis in the treatment of surgical sciatica]. Neuro-Chirurgie, 1985, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Length of Stay; Lumbar Vertebrae; Male; Microsurgery; Middle Aged; Sacrum; Sciatica	1985
Chemonucleolysis in the treatment of lumbar disc disease. British journal of sports medicine, 1985, Volume: 19, Issue:1 Topics: Adolescent; Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Myelography; Sciatica; Tomography, X-Ray Computed	1985
Microdiscectomy versus chemonucleolysis. Neurosurgery, 1985, Volume: 16, Issue:5 Topics: Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Microsurgery; Middle Aged; Postoperative Complications; Sciatica	1985
A case report on nonresolving conservative care of low back pain and sciatic radicular syndrome. Journal of manipulative and physiological therapeutics, 1985, Volume: 8, Issue:2 Topics: Adult; Chiropractic; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Radiography; Sciatica	1985
A comparison of discectomy and chemonucleolysis. Clinical orthopaedics and related research, 1985, Issue:200 Topics: Chymopapain; Costs and Cost Analysis; Epidemiologic Methods; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Length of Stay; Reoperation; Sciatica	1985