1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt has been researched along with Disc, Herniated in 349 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 263 (75.36) | 18.7374 |
| 1990's | 72 (20.63) | 18.2507 |
| 2000's | 11 (3.15) | 29.6817 |
| 2010's | 3 (0.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiba, K; Matsuyama, Y | 1 |
| Eastmond, CJ; Rithchie, IK; Sabboubeh, AF; Vavdha, M; Wardlaw, D | 1 |
| Downing, M; Eastmond, CJ; Rithchie, IK; Sabboubeh, AF; Vavdha, M; Wardlaw, D | 1 |
| Felder-Puig, R; Geiger-Gritsch, S; Gyimesi, M; Mittermayr, T | 1 |
| Chell, J; Mulholland, RC; Wilson, LF | 1 |
| Benoist, M; Deburge, A; Lassale, B; Nizard, M; Parent, H | 2 |
| SAUNDERS, EC | 1 |
| Andreula, C; Leonardi, M; Muto, M | 1 |
| Hara, Y; Haro, H; Kato, T; Komori, H; Shinomiya, K; Spengler, DM; Tagawa, M | 1 |
| Hirsch, JA; Pomerantz, SR | 1 |
| Hoogland, T; Miklitz, B; Ramirez, A; Schubert, M | 1 |
| Castilho, EA; Couto, JM; Menezes, PR | 1 |
| Gibson, JN; Waddell, G | 1 |
| Benoist, M; Busson, J; Cauchoix, J; Deburge, A; Heripret, G; Rigot, J | 1 |
| Weir, B | 1 |
| Sorrells, RB | 1 |
| Benoist, M; Busson, J; Deburge, A | 1 |
| Fager, CA | 4 |
| Benoist, M; Deburge, A; Rocolle, J | 3 |
| Brock, M; Curio, G; Görge, HH | 1 |
| Fisher, RG | 1 |
| Gunby, P | 2 |
| Andersson, G; Ejeskär, A; Herberts, P; Irstam, L; Lysell, E; Nachemson, A; Peterson, LE | 1 |
| Linson, MA | 1 |
| Murray, J | 1 |
| Boyd, RJ; Burton, C; Ford, LT; Hejna, WJ; Javid, MJ; Millett, DK; Newton, SE; Nordby, EJ; Thisted, R; Whisler, WW; Widell, EH; Wiltse, LL | 1 |
| Hejna, WF; Sinkora, G | 1 |
| Bowness, JM; Parkinson, D | 1 |
| Musolf, JM | 1 |
| Riggins, RS; Whitesides, TE | 1 |
| Maida, MJ | 1 |
| Wiltse, LL | 1 |
| Bernstein, IL | 1 |
| Javid, MJ | 2 |
| Deutman, R | 3 |
| Bakay, RA; Tindall, GT; Tindall, SC; Wood, JH | 1 |
| Benoist, M; Bouillet, R; Mulholland, R | 1 |
| Bouillet, R | 3 |
| Aidem, H; Brown, L; Brown, S; George, W; Green, JR; Harrington, T; Hoffman, G; Johnson, R; Shetter, A; Sonntag, V | 1 |
| Hall, BB; McCulloch, JA | 1 |
| Eguro, H | 1 |
| Nordby, EJ | 4 |
| Goldsmith, MF | 1 |
| Fuss, M | 1 |
| Apfelbach, H | 1 |
| Moss, V | 1 |
| Cecile, JP; Cipel, L; Debroucker, R; Descamps, C; Desmarchelier, F; Dufour, R; Foucart, H; Vincent, G | 1 |
| Knodel, LC; Simmons, JW; Stavinoha, WB | 1 |
| Watts, C | 2 |
| Brock, M; Curio, G; Görge, HH; Roggendorf, W | 1 |
| Floman, Y; Gomori, JM | 1 |
| Fleming, FW | 1 |
| Bagshaw, RJ; Bloom, MJ; Bruno, LA; Cohen, AM; Domino, K; Lupo, SE; Smith, DS; Star, AM | 1 |
| Agre, K; McDermott, DJ; Smith, WS; Wilson, RR | 1 |
| Gaines, R; Watts, C | 1 |
| Speck, G | 1 |
| Deutman, R; Konings, JG; Williams, FJ | 2 |
| Ray, CD | 1 |
| Crawshaw, C; Frazer, AM; Merriam, WF; Mulholland, RC; Webb, JK | 1 |
| Postacchini, F | 1 |
| van Alphen, HA | 2 |
| McManus, F; Stephens, MM | 1 |
| Weitz, EM | 1 |
| Brian, JE; Chadduck, WM; Westerman, GR | 1 |
| Kaiser, JC; Mall, JC | 1 |
| Arndt, L; Calenoff, E; Crispin, B; Jones, R; Rock, H; Sun, J; Tsay, YG | 1 |
| Arndt, L; Calenoff, E; Crispin, B; Jones, R; McDermott, D; Stern, I; Sun, J; Tsay, YG | 1 |
| Chastanet, P; Cocheteux, P; Delcambre, B; Delfosse, JM | 1 |
| Bellocci, M; McCulloch, JA; Postacchini, F | 1 |
| Bodin, JM; Lavenac, G; Milon, D; Noury, D; Saint-Marc, C; Sauvage, J | 1 |
| Warner, KE | 1 |
| Burton, CV | 1 |
| Benoist, M; Deburge, A; Heripret, G | 1 |
| Aid, T; Floman, Y | 1 |
| Friedman, WA | 1 |
| McManus, F | 1 |
| Drouillard, J; Drouillard, N; Eresue, J; Lavignolle, B; Philippe, JC; Senegas, J; Tavernier, J | 1 |
| Menkes, CJ | 1 |
| Sorbie, C | 1 |
| McCulloch, JA | 4 |
| Benoist, M; Busson, J; Cauchoix, J; Deburge, A; Heripret, G; Nedjar, C | 1 |
| Bersi, G; Vazzoler, A | 1 |
| Hacohen, H; Mattmann, E | 1 |
| Kivelitz, R; Loew, F; Loew, K | 1 |
| Carruthers, CC; Kousaie, KN | 1 |
| Dehove, H | 1 |
| Basso, M; Honoré, M; Jaffar-Bandjee, Z; Lecuire, F; Rebouillat, J; Sorba, L | 1 |
| Nordby, EJ; Wright, PH | 1 |
| Assheuer, J; Castro, WH; Gohlke, KH; Halm, H; Jerosch, J; Meyer, M; Steinbeck, J | 1 |
| Lebkowski, WJ | 1 |
| Gaehle, KE; Lenke, LG; Moore, S; West, S | 1 |
| Baumann, A; Feldmann, L; Kanny, G; Moneret-Vautrin, DA; Pere, P; Roland, J | 1 |
| Fett, H; Hedtmann, A; Krämer, J; Steffen, R | 1 |
| Ford, LT; Linn, RM | 1 |
| Benoist, M | 1 |
| Ando, T; Iwata, H; Kato, F; Kawakami, N; Mimatsu, K | 1 |
| Eggen, PJ; ter Bruggen, JP; Tonino, AJ; Wein, BB | 1 |
| Rydevik, B | 1 |
| Antoniou, J; Dupuis, P; Hadjipavlou, A; Lander, P; Levine, J | 1 |
| Fabris, G; Lavaroni, A; Leonardi, M | 1 |
| Benoist, M; Bonneville, JF; Deburge, A; Gillard, C; Lassale, B; Runge, M; Vazquez-Suarez, J | 1 |
| Fraser, RD; Gunzburg, R; Moore, R; Vernon-Roberts, B | 1 |
| Brock, M; Mayer, HM; Patt, S; Pedretti, L; Schreiner, C | 1 |
| Smith, L | 1 |
| Konings, JG | 1 |
| Boyer, P; de Souza-Lima, A; Drape, JL; Giannetti, A; Jambon, F; Krause, D; Maitrot, D; Orenstein, D; Srour, R; Tongio, J | 1 |
| Hashimoto, A; Kudo, T; Sumi, A | 1 |
| Gosal, HS; Harrison, DJ | 1 |
| Chenelle, AG; Jane, JA; Sagher, O; Szabo, TA | 1 |
| Kim, JS; Lee, IM; Lee, SH; Lee, SJ; Park, KH; Sung, KH; Yoon, SY | 1 |
| Iwata, H; Kato, F; Mimatsu, K; Sugimura, T; Takenaka, O | 1 |
| Garcia-Mata, S; Hidalgo-Ovejero, AM; Izco-Cabezon, T; Martinez-Grande, M | 1 |
| Bradbury, N; Mulholland, RC; Wilson, LF | 1 |
| Baltés Horche, JL; Gómez-Castresana, F; Rodriguez-Navia, IM; Vázquez Herrero, C | 1 |
| Javid, MJ; Nordby, EJ | 2 |
| Maruo, S | 1 |
| Hemminghytt, S; Salvesen, R | 1 |
| Brown, MD | 2 |
| Amundsen, T; Rasmussen, FO; Vandvik, B | 1 |
| Beer, R; Buchelt, M; Kutschera, HP; Lack, W | 1 |
| Corrigan, NT; McManus, F; Mulcahy, D; O'Farrell, DA; Poynton, AR | 1 |
| Brinckmann, P; Frobin, W; Hemminghytt, S; Leivseth, G; Salvesen, R | 1 |
| Deutman, R; Franssen, S; van de Belt, H | 1 |
| Steffen, R; von Bremen-Kühne, R | 1 |
| Haag, P; Meinck, HM; Münkel, K | 1 |
| Burton, AK; Cleary, J; Tillotson, KM | 1 |
| Oppel, S; Rubenthaler, FA; Steffen, R; Wittenberg, RH | 1 |
| Aribit, F; Arnaud, JP; Charissoux, JL | 1 |
| Knighton, R; Roulhac, G; Watts, C | 1 |
| Sussman, BJ | 1 |
| Rocchio, PD; Wiltse, LL | 1 |
| Daughety, JS; Herrick, RB; Hoover, BB | 1 |
| DiMaio, VJ | 1 |
| Briard, JL | 1 |
| Sampson, P | 1 |
| Johnston, J; Martins, AN; Ramirez, A; Schwetschenau, PR | 1 |
| Ford, LT | 2 |
| Javid, M; Massaro, TA | 1 |
| Ford, LT; Gado, M; Gilula, LA; Murphy, WA | 1 |
| Bornstein, I; Kapsalis, AA; Stern, IJ | 1 |
| Krämer, J; Laturnus, H | 1 |
| Holst, RA; Maroon, JC; Osgood, CP | 1 |
| Johnston, J; Martins, AN; Ramirez, A; Schwetschenau, PR; Wiggs, C | 1 |
| Kempe, LG; Kobrine, AI | 1 |
| Connolly, RC | 1 |
| Dubuc, F; Rouleau, C | 1 |
| Huncke, B; McNeill, T; Pesch, RN | 1 |
| Lévy, A | 1 |
| Onofrio, BM | 1 |
| Clark, K; Hutchison, G; Stern, J; Watts, C | 1 |
| Scoville, WB; Silver, D | 1 |
| Shields, CB | 2 |
| Sylvest, J | 1 |
| Evans, C | 1 |
| Russell, AS | 1 |
| Hudgins, WR | 1 |
| Cox, W; Dunn, JE; Johnson, CL | 1 |
| Anger, C; Betheuil, V; Cotty, P; Fouquet, B; Goupille, P; Valat, JP | 1 |
| Auque, J; Gendrault, P; Hepner, H; Marchal, JC | 1 |
| Abdel-Salam, A; Cleary, J; Eyres, KS | 1 |
| Cleary, JE; Eyres, KS; Salam, A | 1 |
| Arevalo, MA; Dominguez, J; Ferrández, L; Ramos, L; Usabiaga, J | 1 |
| Brautaset, NJ; Hemminghytt, S; Henriksen, OA; Sand, T | 1 |
| de Weerd, AW; Hoogland, PH; van Leeuwen, RB | 1 |
| Iwata, H; Kato, F; Kawakami, N; Mimatsu, K; Miura, T | 1 |
| Antoniou, J; Hadjipavlou, A; Lander, P | 1 |
| Buttle, DJ; Charles, A; Dando, PM; Jenner, JR | 1 |
| Adair, IV; Hamilton, A; Kernohan, WG; Mollan, RA; Muralikuttan, KP | 1 |
| Fraser, RD; Gogan, WJ | 1 |
| Fry, TR; Johnson, AL | 1 |
| Macnab, I; McCulloch, JA; Nachemson, A; Transfeldt, EE; Tregonning, GD | 1 |
| Brock, M; Mayer, HM; Pedretti, L | 1 |
| Braun, JP; Million, S; Patay, Z; Schmutz, G; Tajahmady, T; Tournade, A | 1 |
| Dei-Anang, K; Mader, U; Weigand, H | 1 |
| Alcalay, M; Azais, I; Bontoux, D; Debiais, F; Garrouste, O; Ingrand, P; Roualdes, G | 1 |
| Löchte, W; von Wild, K | 1 |
| Stula, D | 1 |
| Amico, S; Eschard, JP; Liehn, JC; Valeyre, J | 1 |
| Johnston, R | 1 |
| Arndt, D; Griss, P; Henkel, K; Mennel, HD; Pfeiffer, M; Schäfer, T | 1 |
| Nitzschke, E; Schleberger, R; Wahn, U | 1 |
| Bonafe, A; Lazorthes, Y; Richaud, J; Verdie, JC | 1 |
| Andersson, GB; Block, JA; Jeffery, R; Lenz, ME; McNeill, TW; Schnitzer, TJ; Thonar, EJ | 1 |
| Schretlen, E; Spring, M | 1 |
| Brown, MD; Tompkins, JS | 2 |
| Molsberger, A; Schulitz, KP; Wehling, P | 1 |
| Koyanagi, T | 1 |
| Bien, S; Ott, D; Schumacher, M | 1 |
| Austin, RT; Zuk, JA | 1 |
| Alexander, AH; Ayers, WV; Burkus, JK; Mitchell, JB | 1 |
| Moss, J; Roizen, MF | 1 |
| Sutton, JC | 3 |
| Dunsker, SB | 1 |
| Dyck, P | 1 |
| Nachemson, AL | 1 |
| Hejna, W; Lehmann, T; McNeill, T; Spratt, KF; Weinstein, J | 1 |
| Shields, CB; Williams, PE | 1 |
| Ortiz, JE; Rojas, JE | 2 |
| Amor, B; Chevrot, A; Feldman, J; Godefroy, D; Horreard, P; Menkès, CJ; Pallardy, G; Zenny, JC | 1 |
| Jabaay, GA | 1 |
| Parise, M | 1 |
| Baudrillard, JC; Brochot, P; Eschard, JP; Etienne, JC; Gatfosse, M; Gougeon, J; Seignon, B | 1 |
| Ellis, EA; Hill, GM | 1 |
| Amor, B; Chevrot, A; Cormier, C; Menkès, CJ | 1 |
| Belmatoug, N; Benoist, M; Binoche, T; Bourgeois, P; Busson, G; Folinais, D; Frot, B; Lassale, P; Montagner, C; Palazzo, E | 1 |
| Brock, M; Mayer, HM; Piepenbrock, S; Schäffer, J | 1 |
| Kobrine, AI; Zook, BC | 1 |
| Durning, RP; Murphy, ML | 1 |
| Hedtmann, A; Krämer, J; Steffen, R | 2 |
| Alcalay, M; Bontoux, D; Brégeon, C; Fouquet, B; Moneger, M; Valat, JP; Vincent, MH | 1 |
| Cornette, A; Delorme, N; Pichene, M; Polu, JM; Sadoul, P | 1 |
| Blakley, JB; Daffner, RH; Deeb, ZL; Hryshko, FG; Lupetin, AR; Schimel, S | 1 |
| Graham, CE | 2 |
| Maslanka, T; Sideranko, C | 1 |
| Nachemson, A | 1 |
| Dabezies, EJ; Langford, K; Morris, J; Shields, CB; Wilkinson, HA | 1 |
| Amor, B; Carter, H; Chevrot, A; Giraudet, JS; Hirsch, JF; Menkes, CJ | 1 |
| Dias, JJ; Finlay, DB; Grindulis, KA; Nichol, FE | 1 |
| Hellweg, G; Oberhauser, A; Pallua, A; Vogl, G | 1 |
| Alexander, AH; Burkus, JK; Mitchell, JB | 1 |
| Bock-Lamberlin, PR; Rose, FW; Schwonbeck, M | 1 |
| Nachemson, AL; Rydevik, B | 1 |
| Grubb, A | 1 |
| Herron, L; Turner, J; Weiner, P | 1 |
| Allen, WE; Lindsey, RW; Sella, EJ; Southwick, WO | 1 |
| Romy, M | 2 |
| Davis, CM; Kaufman, HH; Radin, EL; Tehranzadeh, J | 1 |
| Mayer, HM | 1 |
| LeBlanc, FE | 1 |
| Hewitt, BE | 1 |
| Freischütz, G; Schenk, KD | 1 |
| Bell, GR; Boumphrey, FR; Hardy, WR; Modic, M; Powers, DF | 1 |
| Finlay, DB; Grindulis, KA; Nichol, FE | 1 |
| Adams, MA; Dolan, P; Hutton, WC | 1 |
| Bernstein, D; Bernstein, IL; Chandler, MJ; Cogen, F; Dolovich, J; Grammer, LC; Schafer, M; Schatz, M; Shaughnessy, JJ; Zeiger, R | 1 |
| Steinmeier, R; von Wild, K | 1 |
| Herron, LD; Turner, J | 1 |
| Gibson, MJ; Mulholland, RC; Szypryt, EP; Worthington, BS | 1 |
| Baulny, D; Castagnera, L; Claverie, JP; Lavignolle, B; Senegas, J; Vital, JM | 1 |
| Cypel, D; Troisier, O | 2 |
| Boisaubert, B; Cypel, D; Gozlan, E; Troisier, O | 1 |
| Baker, HL; Forbes, GS; Houser, OW; Onofrio, BM | 1 |
| Deutman, R; Konings, JG; Wilms, TS | 1 |
| Bochu, M; Megard, M; Vignon, E | 1 |
| Smith, GR | 1 |
| Beck, C; Dabezies, EJ; Shoji, H | 1 |
| Flanagan, N; Smith, L | 1 |
| Apfelbach, H; Dubuc, FL; Javid, M; Nordby, EJ; Simmons, JW | 1 |
| Maciunas, RJ; Onofrio, BM | 2 |
| Hejna, W; Lehmann, TR; McNeill, T; Spratt, K; Weinstein, JN | 1 |
| Field, BT; Spencer, CW; Thomas, JC; Widell, EH; Wiltse, LL; Zindrick, MR | 1 |
| Boyd, R; Huddleston, J; Mansfield, F; Polivy, K | 1 |
| Zampella, EJ; Zeiger, HE | 1 |
| Merz, B | 1 |
| Buttle, DJ; Dixon, AK; Jenner, JR | 1 |
| Loew, F | 1 |
| Dickhaus, E; Watts, C | 1 |
| Herkowitz, HN; Mulawka, SM; Weslowski, DP | 1 |
| Chung, BU; Flanagan, MN | 1 |
| Jacob, HA; Suezawa, Y | 1 |
| Bradford, DS; Oegema, TR; Suguro, T | 1 |
| Buckley, J; Gibson, MJ; Mulholland, RC; Worthington, BS | 1 |
| Pon, A; Schlegel, KF; Seifert, J | 1 |
| Bachmann, B; Biscoping, J; Hempelmann, G; Müller, U | 1 |
| Abrahamson, M; Barrett, AJ; Buttle, DJ | 1 |
| Bonafe, A; Lagarrigue, J; Lazorthes, Y; Richaud, J; Roger, B; Verdie, JC | 1 |
| Houtteville, JP; Toumi, K | 1 |
| Salvi, V | 1 |
| Brown, BM; Dion, G; Ono, H; Stark, EH | 1 |
| Kant, AP; Sepulveda, R | 1 |
| Bosch, A; Buchman, A; Whisler, WW; Wichter, MD; Wright, RB | 1 |
| Green, JR; Harrington, TR; Nehls, DG | 1 |
| Fraser, RD | 1 |
| Ghosh, P; Taylor, TK | 2 |
| Brock, M; Mayer, HM | 1 |
| Agre, K; Brim, M; Demma, FJ; McDermott, DJ; Nelson, J; Thisted, RA; Wilson, RR | 1 |
| Harway, RA | 1 |
| Nazarian, S | 1 |
| Farine, I; Ganel, A; Horoszowski, H; Israeli, A | 1 |
| Berkson, B; Firfer, R; Primack, ML; Zakhary, MG | 1 |
| Abla, A; Maroon, JC | 1 |
| Arnoczky, SP; Kahanovitz, N; Kummer, F | 1 |
| Bruszer, GV; Mascoli, C; Nelson, JC; Sagona, MA; Serkes, K | 1 |
| Cogen, FC; Goldstein, M; Zweiman, B | 1 |
| Haney, PL; Mootz, RD | 1 |
| Benoist, M; Croizier, A; Guéant, JL; Laxenaire, MC; Moneret-Vautrin, DA | 1 |
| Arpin, EJ; Shields, CB | 1 |
| Haines, SJ | 1 |
| Gentry, LR; Javid, MJ; Sackett, JF; Strother, CM; Turski, PA | 2 |
| Bernstein, DI; Bernstein, IL; Gallagher, JS; Ulmer, A | 1 |
| MacDiarmid, A; Welsh, P | 1 |
| Kesselring, J | 1 |
| Javid, MJ; Ramirez, LF | 1 |
| Goldstein, G; Gross, PF | 1 |
| Knox, DL | 1 |
| Brock, M; Kaden, B; Mayer, HM; Wehr, M | 1 |
| Bosacco, SJ | 1 |
| Farfan, HF | 1 |
| Canham, WD; Dolovich, J; McCulloch, JA | 1 |
| Bruszer, G; Mascoli, CC; Pearson, F; Sagona, MA; Serkes, K | 1 |
| Lorenz, M; McCulloch, J | 1 |
| Wilkinson, HA | 1 |
| Fraser, R | 1 |
31 review(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Disc, Herniated
| Article | Year |
|---|---|
Condoliase for treatment of lumbar disc herniation.
Topics: Chymopapain; Glucuronidase; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Japan; Lyases | 2019 |
[Chemonucleolysis and intradiscal electrothermal therapy: what is the current evidence?].
Topics: Chymopapain; Collagenases; Combined Modality Therapy; Diskectomy; Evidence-Based Medicine; Humans; Hyperthermia, Induced; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microsurgery; Oxygen; Ozone; Pain Measurement; Patient Satisfaction; Postoperative Complications; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2009 |
Interventional spinal procedures.
Topics: Bone Cements; Chymopapain; Fluoroscopy; Humans; Injections; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Polymethyl Methacrylate; Radiography, Interventional; Spinal Diseases; Spine | 2004 |
Chemonucleolysis in lumbar disc herniation: a meta-analysis.
Topics: Chymopapain; Collagenases; Controlled Clinical Trials as Topic; Databases, Bibliographic; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Placebos; Randomized Controlled Trials as Topic | 2007 |
Surgical interventions for lumbar disc prolapse: updated Cochrane Review.
Topics: Chymopapain; Cicatrix; Diskectomy; Dura Mater; Endoscopy; Gels; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laser Therapy; Lumbar Vertebrae; Neurosurgical Procedures; Postoperative Complications; Randomized Controlled Trials as Topic; Sciatica; Treatment Outcome | 2007 |
[Chemonucleolysis in the treatment of sciatica caused by herniated disk].
Topics: Anaphylaxis; Animals; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Radiography; Sciatica | 1984 |
[Chemonucleolysis as an alternative to open surgical treatment of lumbar herniated disk].
Topics: Aftercare; Anesthesia, General; Anesthesia, Local; Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Microbial Collagenase; Spinal Puncture | 1984 |
Update and review of chemonucleolysis.
Topics: Anaphylaxis; Animals; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Endopeptidases; Follow-Up Studies; Hemorrhage; Humans; Intervertebral Disc Displacement | 1984 |
Efficacy of chymopapain in chemonucleolysis. A review.
Topics: Chymopapain; Diskectomy; Diskectomy, Percutaneous; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Treatment Outcome | 1994 |
Chemonucleolysis. Personal history, trials, and tribulations.
Topics: Animals; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography | 1993 |
Chymopapain chemonucleolysis.
Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Sciatica | 1993 |
Lumbar chymopapain nucleolysis.
Topics: Chymopapain; Cost-Benefit Analysis; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Morbidity | 1996 |
[The conservative treatment for lumbar disc herniation].
Topics: Analgesia, Epidural; Anti-Inflammatory Agents; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Outpatients; Remission, Spontaneous; Steroids | 1996 |
Update on chemonucleolysis.
Topics: Animals; Chondroitin Lyases; Chymopapain; Collagenases; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Meta-Analysis as Topic; Randomized Controlled Trials as Topic | 1996 |
[Lumbar disk prolapses and radiological spinal intervention. What do the randomized controlled trials say?].
Topics: Chymopapain; Diskectomy, Percutaneous; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography; Randomized Controlled Trials as Topic | 1998 |
[Chemonucleolysis. Development, experiences, prospects].
Topics: Biomechanical Phenomena; Chymopapain; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Prospective Studies; Radiography; Randomized Controlled Trials as Topic | 1999 |
[Late myelopathy after chemonucleolysis. Case report and review of the literature].
Topics: Chymopapain; Drug Eruptions; Female; Follow-Up Studies; Humans; Informed Consent; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Malpractice; Middle Aged; Neurologic Examination; Paraplegia; Sensation Disorders; Spinal Cord Diseases | 1999 |
Continuing experience with chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Patient Selection | 2000 |
Chymopapain treatment of intervertebral disc disease.
Topics: Anaphylaxis; Animals; Arachnoiditis; Catalysis; Cats; Causalgia; Chemical Phenomena; Chemistry; Chymopapain; Diagnostic Errors; Dogs; Drug Hypersensitivity; Endopeptidases; Follow-Up Studies; Glycosaminoglycans; Guinea Pigs; Humans; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Intervertebral Disc; Intervertebral Disc Displacement; Rabbits; Spinal Cord Diseases; Time Factors | 1975 |
Inadequacies and hazards of chymopapain injections as treatment for intervertebral disc disease.
Topics: Adult; Animals; Arachnoiditis; Back Pain; Cats; Cerebrovascular Disorders; Chymopapain; Dogs; Drug Hypersensitivity; Endopeptidases; Headache; Hemiplegia; Humans; Inflammation; Intervertebral Disc; Intervertebral Disc Displacement; Paraplegia; Rabbits; Sensation; Spasm; Subarachnoid Hemorrhage; Syndrome; Urinary Bladder, Neurogenic | 1975 |
The case for chemonucleolysis in discogenic sciatica. A review.
Topics: Animals; Chymopapain; Evaluation Studies as Topic; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Sciatica; Treatment Outcome | 1992 |
Clinical and ultrastructural analysis of failures in chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Treatment Outcome | 1992 |
Chemonucleolysis for treatment of intervertebral disk disease.
Topics: Animals; Chymopapain; Dog Diseases; Dogs; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microbial Collagenase | 1991 |
Diagnostic and therapeutic technology assessment. Chemonucleolysis for herniated lumbar disk.
Topics: American Medical Association; Anaphylaxis; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Sex Factors; Technology Assessment, Biomedical; United States | 1989 |
Advances in low-back pain.
Topics: Animals; Back Pain; Biomechanical Phenomena; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Movement; Pressure; Rest; Sciatica; Spinal Diseases; Spondylolisthesis; Traction | 1985 |
[Treatment by nucleolysis using chymopapain of disk hernias of purely lumbalgic form].
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1988 |
Recent advances in the treatment of low back pain.
Topics: Animals; Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Movement; Physical Exertion; Posture; Pressure; Sciatica; Stress, Mechanical; Stress, Psychological; Traction | 1985 |
Chemonucleolysis for sciatica. A critical review.
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Sciatica | 1988 |
Safer proteinase treatment of sciatica. A biochemical preview of chymopapain inhibitors.
Topics: Chymopapain; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Intervertebral Disc Displacement; Protease Inhibitors; Sciatica | 1988 |
Update on chymopapain.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Local; Causalgia; Cerebral Hemorrhage; Chymopapain; Droperidol; Endopeptidases; Fentanyl; Humans; Injections; Intervertebral Disc Displacement; Intracranial Embolism and Thrombosis; Middle Aged; Neuroleptanalgesia; Paraplegia; Premedication | 1985 |
[Therapy of acute lumbar disk herniation].
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae | 1985 |
37 trial(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Disc, Herniated
| Article | Year |
|---|---|
Prospective randomized trial of chemonucleolysis compared with surgery for soft disc herniation with 1-year, intermediate, and long-term outcome: part I: the clinical outcome.
Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Diskectomy; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Leg; Lumbar Vertebrae; Male; Middle Aged; Pain; Postoperative Complications; Prospective Studies; Sacrum; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult | 2013 |
Prospective randomized trial of chemonucleolysis compared with surgery for soft disc herniation with 1-year, intermediate, and long-term outcome: part II: the radiological outcome.
Topics: Adolescent; Adult; Aged; Chymopapain; Diskectomy; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Radiography; Sacrum; Time Factors; Treatment Outcome; Young Adult | 2013 |
Transforaminal posterolateral endoscopic discectomy with or without the combination of a low-dose chymopapain: a prospective randomized study in 280 consecutive cases.
Topics: Adult; Chymopapain; Combined Modality Therapy; Decompression, Surgical; Diskectomy; Endoscopy; Female; Follow-Up Studies; Humans; Injections, Intralesional; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Minimally Invasive Surgical Procedures; Patient Satisfaction; Postoperative Complications; Prospective Studies; Recovery of Function; Recurrence; Sciatica; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2006 |
Surgery versus chemonucleolysis for herniated lumbar discs. A prospective study with random assignment.
Topics: Adult; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Random Allocation | 1983 |
Safety and efficacy of chymopapain (Chymodiactin) in herniated nucleus pulposus with sciatica. Results of a randomized, double-blind study.
Topics: Adult; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Random Allocation; Sciatica; Sex Factors | 1983 |
A tale of two drugs: urea and chymopapain. The 1982 Percival Bailey Oration.
Topics: Chymopapain; Clinical Trials as Topic; Endopeptidases; History of Medicine; Humans; Intervertebral Disc Displacement; Intracranial Pressure; Neurosurgery; Urea | 1983 |
Chymopapain in intradiscal therapy.
Topics: Anaphylaxis; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Random Allocation | 1983 |
Update and review of chemonucleolysis.
Topics: Anaphylaxis; Animals; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Endopeptidases; Follow-Up Studies; Hemorrhage; Humans; Intervertebral Disc Displacement | 1984 |
[Chemonucleolysis and low backache].
Topics: Adult; Age Factors; Chymopapain; Clinical Trials as Topic; Endopeptidases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Middle Aged | 1984 |
Chemonucleolysis in the treatment of lumbar disc protrusion.
Topics: Chymopapain; Clinical Trials as Topic; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy | 1981 |
Chemonucleolysis for relief of sciatica due to a herniated intervertebral disc.
Topics: Adult; Chymopapain; Clinical Trials as Topic; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Ontario; Random Allocation; Sciatica | 1981 |
[Chemonucleolysis and percutaneous discotomy--value in treatment of lumbar intervertebral disk displacement].
Topics: Adult; Chymopapain; Collagenases; Endoscopes; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Neurologic Examination; Postoperative Complications; Prospective Studies | 1994 |
A randomized, double-blind study to compare low-dose with standard-dose chymopapain in the treatment of herniated lumbar intervertebral discs.
Topics: Adult; Aged; Chymopapain; Double-Blind Method; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Treatment Outcome | 1993 |
[Comparison of percutaneous manual and endoscopic laser diskectomy with chemonucleolysis and automated nucleotomy].
Topics: Adult; Aged; Automation; Chymopapain; Endoscopy; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laser Therapy; Magnetic Resonance Imaging; Male; Middle Aged; Postoperative Care; Tomography, X-Ray Computed | 1996 |
Adolescent disc protrusions. A long-term follow-up of surgery compared to chymopapain.
Topics: Activities of Daily Living; Adolescent; Adult; Back Pain; Chymopapain; Disability Evaluation; Employment; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Length of Stay; Male; Pain; Pain Measurement; Treatment Outcome | 1996 |
Do human lumbar discs reconstitute after chemonucleolysis? A 7-year follow-up study.
Topics: Chymopapain; Double-Blind Method; Feasibility Studies; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Observer Variation; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome | 1999 |
Single-blind randomised controlled trial of chemonucleolysis and manipulation in the treatment of symptomatic lumbar disc herniation.
Topics: Adolescent; Adult; Chymopapain; Costs and Cost Analysis; Disability Evaluation; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Manipulation, Spinal; Middle Aged; Prospective Studies; Sciatica; Single-Blind Method; Surveys and Questionnaires; Treatment Outcome | 2000 |
Chymopapain: a case study in federal drug regulation.
Topics: Chymopapain; Clinical Trials as Topic; Endopeptidases; History, 20th Century; Humans; Injections; Intervertebral Disc Displacement; Legislation, Drug; Placebos; United States; United States Food and Drug Administration | 1978 |
Double-blind evaluation of chemonucleolysis for herniated lumbar discs. Late results.
Topics: Adult; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Laminectomy; Male; Myelography; Placebos | 1978 |
[Treatment of lumbar intervertebral disc lesions by intradiscal instillation of pressurereducing substances (author's transl)].
Topics: Adolescent; Adult; Aprotinin; Chymopapain; Clinical Trials as Topic; Dura Mater; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Water-Electrolyte Balance | 1975 |
Chymopapain in the treatment of ruptured lumbar discs. Preliminary experience in 48 patients.
Topics: Adult; Aged; Anaphylaxis; Chymopapain; Clinical Trials as Topic; Endopeptidases; Humans; Intervertebral Disc Displacement; Middle Aged | 1976 |
Double-blind evaluation of intradiscal chymopapain for herniated lumbar discs. Early results.
Topics: Adult; Chymopapain; Clinical Trials as Topic; Drug Evaluation; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged | 1976 |
Clinical and ultrastructural analysis of failures in chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Treatment Outcome | 1992 |
Low-dose, low-volume chemonucleolysis. A biochemical study.
Topics: Adult; Chymopapain; Female; Glycosaminoglycans; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Prospective Studies; Sciatica | 1992 |
A prospective randomized trial of chemonucleolysis and conventional disc surgery in single level lumbar disc herniation.
Topics: Adult; Chymopapain; Costs and Cost Analysis; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Prospective Studies; Time Factors; Treatment Outcome | 1992 |
Chymopapain. A 10-year, double-blind study.
Topics: Adult; Chymopapain; Double-Blind Method; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Sodium Chloride; Time Factors; Treatment Outcome | 1992 |
Chymopapain versus conventional surgery for lumbar disc herniation. 10-year results of treatment.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Chymopapain; Combined Modality Therapy; Diskectomy; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Observer Variation; Pain; Postoperative Complications; Recurrence; Reoperation; Time Factors; Treatment Outcome; Workers' Compensation | 1991 |
[Treatment of lumbar disk hernia by intra-disk injection of chymopapain or triamcinolone hexacetonide. Comparative study of 80 cases].
Topics: Adult; Aged; Chymopapain; Double-Blind Method; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Randomized Controlled Trials as Topic; Triamcinolone Acetonide | 1990 |
[Chemonucleolysis with chymopapain in lumbar disk hernia. Randomized comparative study with operated patients].
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1990 |
[Double-blind study of the treatment of disc lumbosciatica by chemonucleolysis].
Topics: Adult; Aged; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Sciatica; Time Factors | 1986 |
[Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months].
Topics: Adult; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Injections, Spinal; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation; Sciatica; Triamcinolone Acetonide | 1988 |
Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Double-Blind Method; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Middle Aged; Muscular Diseases; Random Allocation; Sciatica; Spasm; Spine | 1988 |
Sciatica--management by chemonucleolysis versus surgical discectomy.
Topics: Chymopapain; Clinical Trials as Topic; Double-Blind Method; Humans; Injections; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Random Allocation; Sciatica | 1986 |
[Clinical evaluation of Chymodiactin and post-marketing surveillance].
Topics: Chymopapain; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Product Surveillance, Postmarketing; Random Allocation | 1986 |
Tropical fruit in the treatment of lumbar disc prolapse. A topical issue.
Topics: Chymopapain; Clinical Trials as Topic; Endopeptidases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Time Factors | 1985 |
Chymodiactin in patients with herniated lumbar intervertebral disc(s). An open-label, multicenter study.
Topics: Adolescent; Adult; Anaphylaxis; Chymopapain; Clinical Trials as Topic; Double-Blind Method; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Iothalamate Meglumine; Male; Middle Aged; Radiography; Random Allocation; Spasm | 1985 |
The chymopapain clinical trials.
Topics: Adolescent; Adult; Aged; Chymopapain; Clinical Trials as Topic; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Middle Aged; Risk | 1985 |
283 other study(ies) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Disc, Herniated
| Article | Year |
|---|---|
Adolescent disc protrusions. A long term follow-up of chymopapain therapy.
Topics: Adolescent; Chi-Square Distribution; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Treatment Outcome; Young Adult | 1992 |
Lumbar discal herniation in the elderly: long-term results of chymopapain chemonucleolysis.
Topics: Age Factors; Aged; Aged, 80 and over; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Longitudinal Studies; Lumbar Vertebrae; Male; Middle Aged; Patient Satisfaction; Peptide Hydrolases; Treatment Outcome | 1993 |
TREATMENT OF THE CANINE INTERVERTEBRAL DISC SYNDROME WITH CHYMOPAPAIN.
Topics: Animals; Chymopapain; Dog Diseases; Dogs; Drug Therapy; Endopeptidases; Intervertebral Disc; Intervertebral Disc Degeneration; Intervertebral Disc Displacement | 1964 |
Experimental studies on the effects of recombinant human matrix metalloproteinases on herniated disc tissues--how to facilitate the natural resorption process of herniated discs.
Topics: Adult; Animals; Chymopapain; Dogs; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinase 7; Middle Aged; Organ Culture Techniques; Proteoglycans; Rabbits; Recombinant Proteins | 2005 |
Intradiscal therapies for discogenic pain.
Topics: Chymopapain; Diskectomy, Percutaneous; Humans; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Patient Selection | 2006 |
[Treatment of disk sciatica by chemonucleolysis. 120 cases].
Topics: Acute Disease; Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica | 1982 |
Lumbar discectomy or chemonucleolysis: pros and cons.
Topics: Back Pain; Chymopapain; Endopeptidases; Evaluation Studies as Topic; Humans; Injections, Spinal; Intervertebral Disc; Intervertebral Disc Displacement; Prospective Studies | 1982 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Nerve Compression Syndromes; Spinal Nerve Roots | 1983 |
The age-old back problem. New fad, same fallacies.
Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Laminectomy; Prognosis; Sciatica; Spinal Fusion | 1984 |
[Surgery in failure of nucleolysis of lumbar disk hernia].
Topics: Adolescent; Adult; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Spinal Stenosis | 1984 |
Injection therapy for herniated disks. Background and usefulness.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Laminectomy; Microbial Collagenase; Sciatica; Tomography, X-Ray Computed | 1984 |
Chymopapain: tropical tree to surgical suite.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; United States; United States Food and Drug Administration | 1983 |
What is intradiscal therapy, anyway?
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1983 |
Chymopapain for herniated lumbar discs.
Topics: Chymopapain; Endopeptidases; Female; Femoral Nerve; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Nerve Compression Syndromes; Sciatic Nerve | 1983 |
Fees for chemonucleolysis injection of chymopapain may be too high.
Topics: Chymopapain; Endopeptidases; Fees, Medical; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Sacrum | 1983 |
[Chemonucleolysis valid alternative to lumbar discoidectomy].
Topics: Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Radiography; Sciatica | 1983 |
Chemonucleolysis of herniated lumbar discs.
Topics: Adolescent; Adult; Chymopapain; Endopeptidases; Evaluation Studies as Topic; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1983 |
Increased glycosaminoglycan excretion after chymopapain injection of intervertebral discs.
Topics: Chymopapain; Endopeptidases; Glycosaminoglycans; Humans; Intervertebral Disc Displacement | 1983 |
Chemonucleolysis. A new approach for patients with herniated intervertebral disks.
Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Male; Nursing Care | 1983 |
Chemonucleolysis for herniated nucleus pulposus.
Topics: Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male; Nerve Compression Syndromes; Spinal Nerve Roots | 1983 |
Chymopapain for herniated lumbar disc disease.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Patient Discharge; Postoperative Care; Radiography | 1983 |
Chemonucleolysis in the treatment of lumbar disc disease.
Topics: Adult; Aged; Anaphylaxis; Animals; Chymopapain; Dogs; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Methods; Middle Aged; Myelography; Time Factors | 1983 |
Adverse effects of chemonucleolysis.
Topics: Anaphylaxis; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male; Risk; Sex Factors | 1983 |
[Chemonucleolysis in patients with herniated lumbar nucleus pulposus].
Topics: Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Radiography | 1983 |
Treatment of herniated lumbar discs with chymopapain.
Topics: Anaphylaxis; Animals; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Postoperative Care | 1983 |
Chemonucleolysis. Results of a European survey.
Topics: Chymopapain; Endopeptidases; Europe; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Sciatica | 1983 |
Complications of discal hernia therapy. Comparative study regarding surgical therapy and nucleolysis by chymopapain.
Topics: Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Middle Aged; Postoperative Complications | 1983 |
Chymopapain and lumbar disc protusion.
Topics: Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male | 1983 |
Anaphylactic reactions following the intradiscal injection of chymopapain under local anesthesia.
Topics: Adult; Aged; Anaphylaxis; Anesthesia, Local; Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1983 |
Transverse myelitis following chemonucleolysis. Report of a case.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Myelitis; Myelitis, Transverse; Paraplegia | 1983 |
Chymopapain injection--an often fruitless endeavor?
Topics: Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male | 1984 |
Disk therapy without surgery.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Operating Room Nursing | 1984 |
Technique for chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Patient Care Planning; Radiography | 1984 |
Chemonucleolysis: enzyme eases back pain.
Topics: Adult; Anaphylaxis; Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc Displacement; Postoperative Care; Posture | 1983 |
[Results of discolysis with chymopapain. 300 cases].
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Radiography; Sciatica | 1983 |
Mechanism of action of chymopapain in ruptured lumbar disc disease.
Topics: Aging; Animals; Biomechanical Phenomena; Chemical Phenomena; Chemistry; Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbosacral Region; Myelography | 1983 |
Morphological alterations of the degenerated lumbar disc following chemonucleolysis with chymopapain.
Topics: Adult; Basophils; Cartilage; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbosacral Region; Male; Microscopy; Microscopy, Electron, Scanning; Middle Aged; Spinal Diseases | 1984 |
Chymopapain disk-injection therapy. Modified lumbar approach.
Topics: Adult; Chymopapain; Endopeptidases; Female; Fluoroscopy; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male | 1984 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement | 1984 |
Treatment of protruded intervertebral discs.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1984 |
Sudden hypotension with a test dose of chymopapain.
Topics: Adult; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Hypersensitivity, Immediate; Hypotension; Intervertebral Disc Displacement; Intraoperative Period; Lumbar Vertebrae; Male; Premedication; Urticaria | 1984 |
Chymopapain injection.
Topics: Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male | 1984 |
Chemonucleolysis. The treatment of lumbar intervertebral disc disease by the intradiscal injection of chymopapain.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae | 1983 |
Chymopapain--a counter comment.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Spinal Diseases | 1984 |
Chymopapain in intradiscal therapy.
Topics: Cardiac Output; Chymopapain; Dopamine; Endopeptidases; Humans; Intervertebral Disc Displacement | 1984 |
The effects of chemonucleolysis as demonstrated by computerised tomography.
Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbosacral Region; Male; Middle Aged; Myelography; Prospective Studies; Sciatica; Time Factors; Tomography, X-Ray Computed | 1984 |
Danger of intravenous injection during chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement | 1984 |
A comparison of surgery and chemonucleolysis in the treatment of sciatica. A prospective randomized trial.
Topics: Adolescent; Adult; Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Middle Aged; Outcome and Process Assessment, Health Care; Prospective Studies; Random Allocation | 1984 |
Chemonucleolysis in the treatment of prolapsed intervertebral disc. Early results.
Topics: Adult; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Postoperative Care; Preoperative Care; Sacrum; Time Factors; Tomography, X-Ray Computed | 1984 |
Chymopapain administration procedures modified.
Topics: Chymopapain; Drug Labeling; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Nervous System Diseases | 1984 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc Displacement; Male; Pain Management | 1984 |
Paraplegia following chymopapain injection. A case report.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Laminectomy; Male; Middle Aged; Paraplegia; Spinal Fusion | 1984 |
Intravenous injection during chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Injections, Intravenous; Intervertebral Disc Displacement; Male; Middle Aged | 1984 |
Septic complications of chemonucleolysis.
Topics: Adult; Aged; Bacterial Infections; Chymopapain; Empyema; Endopeptidases; Epidural Space; Heart Valve Diseases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male; Spinal Diseases; Staphylococcal Infections; Staphylococcus epidermidis | 1984 |
Post-chymopapain (chemonucleolysis)--clinical and computed tomography correlation: preliminary results.
Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Time Factors; Tomography, X-Ray Computed | 1984 |
A preoperative chymopapain sensitivity test for chemonucleolysis candidates.
Topics: Antibody Specificity; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Immunoenzyme Techniques; Immunoglobulin E; Intervertebral Disc Displacement; Lumbar Vertebrae | 1984 |
Chymopapain-induced hypersensitivity following chemonucleolysis.
Topics: Antibody Specificity; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Immunoenzyme Techniques; Immunoglobulin E; Intervertebral Disc Displacement | 1984 |
[Discal nucleolysis in the treatment of common sciatica].
Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica | 1984 |
The "in vivo" effect of chymopapain on intervertebral disc hernia (an ultrastructural study).
Topics: Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male | 1984 |
[Neuroleptanalgesia for chemical nucleolysis].
Topics: Adult; Chymopapain; Droperidol; Endopeptidases; Female; Fentanyl; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Neuroleptanalgesia; Preanesthetic Medication; Radiography | 1984 |
Chemonucleolysis with chymopapain.
Topics: Anaphylaxis; Anesthesia, General; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Sciatica | 1984 |
Conservative management of low back pain.
Topics: Back Pain; Bed Rest; Chymopapain; Humans; Intervertebral Disc Displacement; Nerve Block; Posture; Spinal Fusion; Spine; Stress, Mechanical; Traction | 1981 |
Indications and contra-indications of nucleolysis.
Topics: Cauda Equina; Chymopapain; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Nerve Compression Syndromes; Pregnancy; Sciatica | 1983 |
[Chemonucleolysis].
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement | 1983 |
New techniques for treatment of disk disease.
Topics: Aged; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Methods; Microsurgery; Tomography, X-Ray Computed | 1984 |
Chemonucleolysis of prolapsed lumbar intervertebral discs.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement | 1982 |
[Scanography and chemonucleolysis of herniated discs. Value and limitations in 20 cases].
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Tomography, X-Ray Computed | 1982 |
[Nucleolysis].
Topics: Animals; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement | 1982 |
Chymopapain approved.
Topics: Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Male; United States; United States Food and Drug Administration | 1982 |
[Treatment of intervertebral disk sciatica by chemonucleolysis. Analysis of 56 cases].
Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica | 1981 |
[Segmental epidural analgesia in chemonucleolysis].
Topics: Anaphylaxis; Anesthesia, Epidural; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1981 |
[Chemonucleolysis as an adjunct in the treatment of disk protrusion (author's transl)].
Topics: Administration, Topical; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Laminectomy | 1982 |
Treatment of lumbo-ischialgias of different origins by intradiscal injection of chymopapain (discolysis). Analysis of literature and personal experiences.
Topics: Adolescent; Adult; Bone Diseases; Chymopapain; Endopeptidases; Humans; Inflammation; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Lumbosacral Region; Middle Aged; Pain; Pelvis; Postoperative Complications; Spondylolisthesis | 1982 |
Surgical treatment after chemonucleolysis failure.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement | 1982 |
[Lumbago and sciatica. Chemonucleolysis].
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Radiography | 1982 |
[Long-term result of lumbar disk chemonucleolysis (a 8-12 years follow-up)].
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Spinal Nerve Roots; Tomography, X-Ray Computed | 1994 |
Long-term changes in the magnetic resonance image after chemonucleolysis.
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Time Factors | 1994 |
Percutaneous "disc" disease treatment.
Topics: Chymopapain; Diskectomy, Percutaneous; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement | 1993 |
Lumbar disc herniation. New treatment modalities.
Topics: Adult; Chymopapain; Diskectomy; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Microsurgery; Middle Aged; Operating Room Nursing | 1994 |
Incidence and risk factors for latent sensitization to chymopapain: predictive skin-prick tests in 700 candidates for chemonucleolysis.
Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Factors; Skin Tests | 1994 |
[Herniation of a lumbar disk in the elderly. Results of chemonucleolysis].
Topics: Aged; Aged, 80 and over; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Treatment Outcome | 1993 |
Adult diastematomyelia.
Topics: Adult; Chymopapain; Diskectomy; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Spina Bifida Occulta; Tomography, X-Ray Computed | 1994 |
[Chemonucleolysis and lumbar disk herniation].
Topics: Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Retrospective Studies | 1993 |
The increased signal intensity at the vertebral body endplates after chemonucleolysis demonstrated by magnetic resonance imaging.
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Spinal Osteophytosis; Time Factors | 1993 |
Aseptic spondylodiscitis: a complication of chemonucleolysis? A case report.
Topics: Adult; C-Reactive Protein; Chymopapain; Diagnosis, Differential; Discitis; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging | 1993 |
Chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement | 1993 |
[Chemonucleolysis. Its effectiveness in the treatment of lumbar diskopathies caused by compressive or rotational injuries].
Topics: Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Recurrence; Tomography, X-Ray Computed | 1993 |
Percutaneous treatment of lumbar disc herniation.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Italy; Lumbar Vertebrae | 1993 |
An experimental study comparing percutaneous discectomy with chemonucleolysis.
Topics: Animals; Chymopapain; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography; Sheep | 1993 |
Nucleus pulposus regeneration after chemonucleolysis with chymopapain?
Topics: Adult; Bone Regeneration; Chymopapain; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged | 1993 |
Cervical nucleolysis: indications, technique, results. 190 patients.
Topics: Adult; Brachial Plexus Neuritis; Cervical Vertebrae; Chymopapain; Discitis; Female; Follow-Up Studies; Humans; Injections, Intralesional; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Sensation Disorders; Spinal Puncture; Subarachnoid Hemorrhage; Time Factors; Tomography, X-Ray Computed; Treatment Failure | 1993 |
Experimental chemonucleolysis with chymopapain in canine intervertebral disks.
Topics: Animals; Chymopapain; Dog Diseases; Dogs; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography | 1993 |
Magnetic resonance imaging before chemonucleolysis for lumbar disc prolapse.
Topics: Adult; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Middle Aged | 1995 |
Intraoperative chemonucleolysis as an adjunct to lumbar discectomy.
Topics: Adolescent; Adult; Aged; Chymopapain; Combined Modality Therapy; Diskectomy; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Intraoperative Period; Lumbar Vertebrae; Male; Middle Aged; Postoperative Complications; Retrospective Studies | 1995 |
Experimental chemonucleolysis with chondroitinase ABC in monkeys.
Topics: Animals; Chondroitin Lyases; Chymopapain; Female; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Macaca mulatta; Magnetic Resonance Imaging; Male; Radiography | 1996 |
Intraoperative chemonucleolysis as an adjunct to lumbar discectomy.
Topics: Chymopapain; Combined Modality Therapy; Diskectomy; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae | 1996 |
Cervical chymopapain nucleolysis: MR imaging assessment of chymopapain efficacy.
Topics: Adult; Cervical Vertebrae; Chymopapain; Equipment and Supplies; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Magnetic Resonance Imaging; Middle Aged; Prospective Studies; Tomography, X-Ray Computed; Treatment Outcome | 1996 |
[Chemonucleolysis of lumbar disk prolapse. Choice and complications].
Topics: Adult; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Patient Satisfaction; Surveys and Questionnaires | 1997 |
The lumbar spine--small is beautiful: the Third Annual Ian Macnab Memorial Lecture.
Topics: Canada; Chymopapain; Diskectomy; Diskectomy, Percutaneous; History, 20th Century; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Microsurgery; Orthopedics; Spinal Fusion; Spinal Stenosis | 1997 |
Comparative study of surface displacement in discs following chemonucleolysis and lasernucleotomy.
Topics: Biomechanical Phenomena; Cadaver; Chymopapain; Elasticity; Humans; In Vitro Techniques; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laser Therapy; Lumbar Vertebrae; Multivariate Analysis; Stress, Mechanical | 1998 |
Chymopapain chemonucleolysis: a review of 105 cases.
Topics: Adult; Aged; Chymopapain; Disability Evaluation; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1998 |
Repeat chemonucleolysis is safe and effective.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Recurrence; Retreatment; Retrospective Studies; Treatment Outcome | 1999 |
Five-year results from chemonucleolysis with chymopapain or collagenase: a prospective randomized study.
Topics: Adult; Anaphylaxis; Chymopapain; Collagenases; Diskectomy; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Prospective Studies; Random Allocation; Treatment Outcome | 2001 |
[Long-term 10-year outcome after chemonucleolysis for lumbar disc herniation].
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Retrospective Studies; Time Factors | 2002 |
Preoperative psychological tests as predictors of success of chemonucleolysis in the treatment of the low-back syndrome.
Topics: Adult; Back Pain; Chymopapain; Cornell Medical Index; Endopeptidases; Female; Humans; Hypochondriasis; Hysteria; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Mental Processes; MMPI; Psychological Tests; Psychophysiologic Disorders; Retrospective Studies; Syndrome; Wechsler Scales | 1975 |
Clinical and electromyographic evaluation after chemonucleolysis for lumbar disk disease.
Topics: Back Pain; Chymopapain; Electromyography; Endopeptidases; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Sciatica | 1975 |
Two anaphylactic deaths after chemonucleolysis.
Topics: Adult; Anaphylaxis; Autopsy; Back Pain; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Middle Aged | 1976 |
[Report on a 15-month stay in North America].
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Phlebography | 1976 |
Chemonucleolysis.
Topics: Adult; Back Pain; Chymopapain; Dermatitis, Contact; Endopeptidases; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Postoperative Care; Prospective Studies; Recurrence; Spinal Diseases | 1977 |
Chemonucleolysis by chymopapain.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1979 |
Chemonucleolysis.
Topics: Chymopapain; Drug Evaluation; Edetic Acid; Endopeptidases; Humans; Intervertebral Disc Displacement; Research Design | 1977 |
Analysis of gas in vacuum lumbar disc.
Topics: Chymopapain; Gases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Nitrogen; Radiography; Vacuum | 1977 |
Still dissolving discs?
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1977 |
Correlation between hypersensitivity to parenteral chymopapain and the presence of IgE anti-chymopapain antibody.
Topics: Anaphylaxis; Antibody Specificity; Chymopapain; Endopeptidases; Humans; Immunoglobulin E; Intervertebral Disc Displacement; Radioimmunoassay | 1978 |
Diagnosis and management of neurosurgical problems.
Topics: Chymopapain; Embolization, Therapeutic; Humans; Intervertebral Disc Displacement; Microsurgery; Nervous System Diseases; Neurologic Examination; Pain Management; Seizures; Trigeminal Neuralgia | 1976 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Spinal Diseases | 1977 |
[Lumbo-sciatica and chemonucleolysis].
Topics: Chymopapain; Dexamethasone; Endopeptidases; Humans; Intervertebral Disc Displacement; Sciatica | 1977 |
Chemonucleolysis: evaluation of effectiveness by electromyography.
Topics: Chymopapain; Electromyography; Endopeptidases; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement | 1977 |
[Lumbar disk herniations (authors transl)].
Topics: Chymopapain; Exercise Therapy; Humans; Intervertebral Disc Displacement; Lumbosacral Region; Traction | 1976 |
Injection of cymopapain into intervertebral discs. Preliminary report on 72 patients with symptoms of disc disease.
Topics: Anesthesia, General; Chymopapain; Drug Evaluation; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Myelography | 1975 |
Comparison of intervertebral disc disease treatment by chymopapain injection and open surgery.
Topics: Adult; Arachnoiditis; Causalgia; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Postoperative Complications | 1975 |
Letter: Results of Scoville and Silver's questionnaire on chymopapain.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1975 |
Letter: Chemonucleolysis: an appeal for objectivity.
Topics: Chymopapain; Drug Evaluation; Endopeptidases; Humans; Intervertebral Disc Displacement; Research Design | 1975 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae | 1975 |
[Treatment of disc prolapse by enzymatic breakdown of the nucleus pulposus].
Topics: Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Male | 1975 |
Chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Hydrolysis; Intervertebral Disc Displacement; Methods | 1975 |
Chymopapain chemonucleolysis in lumbar disk disease.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Pain | 1975 |
Letter: Chymopapain chemonucleolysis in lumbar disk disease.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1975 |
Letter: Lumbar disk disease: laminectomy vs chymopapain chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Laminectomy | 1975 |
Treatment of lumbar disks with chymopapain.
Topics: Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Physical Therapy Modalities | 1976 |
[Long-term results of chymopapain chemonucleolysis].
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Retrospective Studies; Sciatica | 1992 |
[Surgery for lumbar disk hernia after chemonucleolysis. Results and analysis. Apropos of 100 cases].
Topics: Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Low Back Pain; Male; Reoperation; Sciatica; Treatment Failure | 1992 |
A new paradiscal injection technique for the relief of back spasm after chemonucleolysis.
Topics: Adult; Back; Back Pain; Bupivacaine; Chymopapain; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Muscle Spasticity | 1992 |
A new paradiscal injection technique for the relief of back spasm after chemonucleolysis.
Topics: Back Pain; Bupivacaine; Chymopapain; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Postoperative Complications | 1992 |
[Lumbar disk prolapse treated with chymopapain].
Topics: Adolescent; Adult; Chymopapain; Contraindications; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1992 |
Chemonucleolysis. Predictive factors.
Topics: Adult; Cerebrospinal Fluid; Chymopapain; Electromyography; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Myelography; Predictive Value of Tests; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome | 1992 |
Serial changes observed by magnetic resonance imaging in the intervertebral disc after chemonucleolysis. A consideration of the mechanism of chemonucleolysis.
Topics: Adolescent; Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Radiography | 1992 |
The effect of chymopapain on low back pain.
Topics: Adult; Back Pain; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Tomography, X-Ray Computed | 1992 |
The results of "lumbar disc surgery" following unsuccessful chemonucleolysis.
Topics: Adult; Chymopapain; Combined Modality Therapy; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Pain; Retrospective Studies; Treatment Outcome | 1991 |
Contribution of discography to the diagnosis and treatment of lumbar disc herniation.
Topics: Chymopapain; Contrast Media; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Ligaments; Lumbar Vertebrae; Spinal Canal; Spinal Puncture; Tomography, X-Ray Computed | 1991 |
[Alternatives to chemonucleolysis].
Topics: Administration, Topical; Anti-Inflammatory Agents; Chymopapain; Drug Hypersensitivity; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Time Factors; Triamcinolone Acetonide | 1991 |
Chemonucleolysis.
Topics: Adolescent; Anaphylaxis; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male | 1991 |
Treatment of sciatica. A comparative survey of complications of surgical treatment and nucleolysis with chymopapain.
Topics: Adolescent; Adult; Back Pain; Chymopapain; Discitis; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Peripheral Nervous System Diseases; Postoperative Complications; Pulmonary Embolism; Sciatica; Thrombophlebitis | 1990 |
[Percutaneous nucleotomy: an alternative to chemonucleolysis?].
Topics: Adult; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microbial Collagenase | 1990 |
[Evaluating performance in lumbar intervertebral disk damage following chemonucleolysis].
Topics: Adolescent; Adult; Aged; Chymopapain; Disability Evaluation; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1990 |
Bone scan and chemonucleolysis.
Topics: Chymopapain; Discitis; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Radionuclide Imaging | 1990 |
Spinal surgery.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microsurgery; Spinal Cord Compression; Spinal Cord Neoplasms; Spinal Diseases; Spine | 1990 |
[Chemonucleolysis].
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement | 1990 |
An update on chymopapain for treating lumbar disc ruptures.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement | 1990 |
Automated percutaneous lumbar discectomy with and without chymopapain pretreatment versus non-automated discoscopy-monitored percutaneous lumbar discectomy. An experimental study in human cadaver spines.
Topics: Chymopapain; Combined Modality Therapy; Equipment Design; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Suction; Surgical Instruments | 1990 |
[Immunologic methods of study for evaluating the risk of anaphylactic reactions in intradisk chymopapain injections].
Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Histamine Release; Humans; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Leukocytes; Patch Tests; Radioallergosorbent Test; Risk | 1986 |
Chemonucleolysis for herniated cervical disc.
Topics: Adult; Cervical Vertebrae; Chymopapain; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Palliative Care | 1988 |
The effect of chemonucleolysis on serum keratan sulfate levels in humans.
Topics: Adult; Aged; Cartilage; Chymopapain; Female; Follow-Up Studies; Glycosaminoglycans; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Keratan Sulfate; Male; Middle Aged; Prospective Studies | 1989 |
Acute disc: trends in treatment.
Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement | 1989 |
Pain response post-chemonucleolysis or disc excision.
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microbial Collagenase; Pain; Pain, Postoperative; Prospective Studies | 1989 |
[Clinical deterioration following chemonucleolysis. Sequestration or neurotoxic complication?].
Topics: Adult; Animals; Chymopapain; Dexamethasone; Diagnosis, Differential; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Nerve Compression Syndromes; Rats; Spinal Nerve Roots; Spinal Stenosis; Synaptic Transmission | 1989 |
[A biochemical analysis of experimental chemonucleolysis].
Topics: Animals; Biomechanical Phenomena; Chymopapain; Dogs; Elasticity; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microbial Collagenase; Viscosity | 1989 |
Diskography with iotrolan before chemonucleolysis with chymopapain.
Topics: Animals; Chymopapain; Contrast Media; Dogs; Drug Interactions; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Iodobenzoates; Lumbar Vertebrae; Myelography; Triiodobenzoic Acids | 1989 |
Epidural adhesions after chymopapain chemonucleolysis.
Topics: Adult; Aged; Chymopapain; Epidural Space; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica; Spinal Canal; Tissue Adhesions | 1989 |
Chemonucleolysis for sciatica.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Sciatica | 1989 |
Chymopapain chemonucleolysis versus surgical discectomy in a military population.
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Length of Stay; Lumbar Vertebrae; Male; Middle Aged; Military Personnel; Postoperative Complications; Prognosis; Retrospective Studies | 1989 |
Adverse reactions to chemonucleolysis: anesthetic considerations.
Topics: Anaphylaxis; Anesthesia; Chymopapain; Endopeptidases; Female; Fluid Therapy; Histamine H1 Antagonists; Humans; Intervertebral Disc Displacement; Laminectomy; Male; Skin Tests | 1985 |
Repeat chemonucleolysis.
Topics: Adolescent; Adult; Anaphylaxis; Chymopapain; Cimetidine; Female; Follow-Up Studies; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Premedication; Recurrence; Risk; Time Factors | 1986 |
Alternatives in the surgical treatment of herniated lumbar disks.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Microsurgery; Spinal Fusion | 1989 |
Paraplegia following chemonucleolysis. A case report and discussion of neurotoxicity.
Topics: Adult; Back Pain; Cauda Equina; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Paraplegia; Subarachnoid Hemorrhage | 1985 |
Lumbar disc herniation. A comparison of the results of chemonucleolysis and open discectomy after ten years.
Topics: Adult; Back Pain; Chymopapain; Consumer Behavior; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Retrospective Studies; Spinal Fusion; Surveys and Questionnaires; Time Factors; Work Capacity Evaluation | 1986 |
Low back pain.
Topics: Arthritis; Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Physical Examination; Psychophysiologic Disorders; Rest; Spinal Cord Neoplasms; Sprains and Strains; Tomography, X-Ray Computed | 1986 |
Low back pain, sciatica and chemonucleolysis: a community hospital experience.
Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica | 1986 |
Chemonucleolysis. Eight- to ten-year follow-up evaluation.
Topics: Adolescent; Adult; Aged; Chymopapain; Disability Evaluation; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Life Style; Lumbar Vertebrae; Male; Middle Aged; Occupations; Surveys and Questionnaires; Time Factors; United States; Workers' Compensation | 1986 |
Chemonucleolysis in the management of lumbar disc disease. A minimum six-year follow-up evaluation.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Canada; Child; Chymopapain; Consumer Behavior; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Recurrence; Surveys and Questionnaires; Time Factors; Workers' Compensation | 1986 |
[Nursing care report. Apropos of a case of lumbosciatica treated with chemonucleolysis].
Topics: Adult; Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Male | 1986 |
[Discal incontinence: a contraindication to chemonucleolysis].
Topics: Chymopapain; Contrast Media; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography | 1986 |
Chemonucleolysis as an alternative to laminectomy for the herniated lumbar disc. Experience with patients in a private orthopedic practice.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Insurance, Health; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Length of Stay; Lumbar Vertebrae; Male; Middle Aged; Workers' Compensation | 1987 |
[Long-term results of chymopapain nucleolysis].
Topics: Adult; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Recurrence; Retrospective Studies; Sciatica | 1988 |
[Anesthesiologic aspects of chemonucleolysis in local anesthesia].
Topics: Adult; Anesthesia, Local; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Intervertebral Disc Displacement; Intradermal Tests; Lumbar Vertebrae; Microbial Collagenase; Risk | 1985 |
[Sciatica and chemonucleolysis].
Topics: Aftercare; Chymopapain; Cimetidine; Diphenhydramine; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement; Methods; Premedication; Sciatica; Spasm | 1985 |
Effects of collagenase and chymopapain on spinal nerves and intervertebral discs of cynomolgus monkeys.
Topics: Animals; Chymopapain; Intervertebral Disc; Intervertebral Disc Displacement; Macaca fascicularis; Male; Microbial Collagenase; Peripheral Nervous System Diseases; Spinal Cord; Spinal Diseases; Spinal Nerve Roots | 1986 |
Lumbar disk disease. Clinical presentation, diagnosis, and treatment.
Topics: Cauda Equina; Chymopapain; Electromyography; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Myelography; Nerve Compression Syndromes; Peripheral Nervous System Diseases; Phlebography; Reflex, Abnormal; Sensation; Spinal Nerve Roots; Thermography; Tomography, X-Ray Computed | 1986 |
[Experiences with intradisk injection treatment with chymopapain and collagenase].
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Microbial Collagenase; Prognosis | 1986 |
Prospective comparative study of intradiscal high-dose and low-dose collagenase versus chymopapain.
Topics: Adult; Cauda Equina; Chymopapain; Follow-Up Studies; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Microbial Collagenase; Middle Aged; Muscle Hypotonia; Nerve Compression Syndromes; Paralysis; Prospective Studies | 1987 |
[Thromboembolism following chemonucleolysis for disk hernia].
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Thromboembolism | 1985 |
Intervertebral disk-space infection after chymopapain injection.
Topics: Adult; Back Pain; Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbosacral Region; Male; Middle Aged; Spinal Diseases; Staphylococcal Infections; Tomography, X-Ray Computed | 1985 |
Chemonucleolysis for sciatica and low back pain.
Topics: Anaphylaxis; Back Pain; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Postoperative Care; Sciatica | 1985 |
An alternative to back surgery--for some patients.
Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Male; Postoperative Care; Sciatica | 1985 |
Dissolving a lifetime of lower back pain with chemonucleolysis.
Topics: Back Pain; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Middle Aged | 1985 |
[Failure of chemonucleolysis and its surgical treatment. Apropos of 268 cases].
Topics: Chymopapain; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiculopathy; Retrospective Studies | 1988 |
Chemonucleolysis of calcified prolapsed intervertebral discs.
Topics: Calcinosis; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Prolapse | 1988 |
[Chemonucleolysis--a possible ambulatory treatment method in lumbar intervertebral disk displacement?].
Topics: Ambulatory Care; Chymopapain; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae | 1988 |
Evaluation and treatment of chemonucleolysis failures.
Topics: Adult; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Pain; Sciatica | 1988 |
[Chemonucleolysis--with extended indications. 4 years clinical experience].
Topics: Cauda Equina; Chymopapain; Combined Modality Therapy; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis | 1988 |
Does the MMPI predict chemonucleolysis outcome?
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Personality Inventory; Prognosis | 1988 |
Duration of symptoms and disc configuration in chemonucleolysis.
Topics: Adult; Aged; Chymopapain; Female; Humans; Infant; Intervertebral Disc Displacement; Male; Middle Aged; Myelography; Prognosis; Prospective Studies; Tomography, X-Ray Computed | 1988 |
Chemonucleolysis technique. New oblique approach requires no measurements.
Topics: Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Radiography | 1986 |
Treatment of lumbar disc disease, 1986.
Topics: Adolescent; Adult; Chymopapain; Female; Humans; Injections; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1986 |
[Incidence and prevention of allergic reactions following chemonucleolysis with chymopapain].
Topics: Anaphylaxis; Chymopapain; Cross-Sectional Studies; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Intradermal Tests; Patch Tests | 1986 |
The classic. Enzyme dissolution of the nucleus pulposus in humans. By Lyman W. Smith. 1964.
Topics: Chymopapain; History, 20th Century; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae | 1986 |
Sensitivity testing with the Chymo-FAST test.
Topics: Chymopapain; Drug Hypersensitivity; Fluorescent Antibody Technique; Humans; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement | 1986 |
Computed tomography scanning after chymopapain injection for herniated nucleus pulposus. A prospective study.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Magnetic Resonance Spectroscopy; Prospective Studies; Time Factors; Tomography, X-Ray Computed | 1987 |
Chemonucleolysis of lumbar intervertebral disc prolapse with chymopapain: outcome after 1 year.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies | 1987 |
The short-term effects of chymopapain on intervertebral discs.
Topics: Adult; Biomechanical Phenomena; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Middle Aged; Movement; Pressure; Stress, Mechanical | 1987 |
Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. A preliminary report.
Topics: Adult; Anaphylaxis; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Skin Tests | 1987 |
[Clinical experience with intradisk chymopapain administration in lumbar intervertebral disk displacement].
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1987 |
A revised objective rating system for patient selection for chymopapain chemonucleolysis.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Life Style; Male; Middle Aged; MMPI; Myelography; Neurologic Examination; Predictive Value of Tests; Tomography, X-Ray Computed | 1987 |
The long-term effect of chemonucleolysis on the intervertebral disc as assessed by magnetic resonance imaging.
Topics: Adolescent; Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Magnetic Resonance Imaging; Male; Middle Aged; Prospective Studies | 1987 |
Chemonucleolysis. Indications and technique.
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Radiography; Retrospective Studies | 1987 |
[The disk tolerance test and disk manometry. Diagnostic and prognostic value before chemonucleolysis].
Topics: Adult; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Manometry; Middle Aged; Prognosis | 1987 |
[Surgery or nucleolysis. Is discography a decisive factor?].
Topics: Adult; Aged; Child; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Prognosis; Radiography | 1987 |
[Results of treatment with intra-disk injection of lekopain in the treatment of herniated lumbar disk].
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1987 |
[Comparative study of the cost of treatment of sciatica by chemonucleolysis and by surgery].
Topics: Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Length of Stay | 1987 |
Correlation of radiological features to failure of lumbar intervertebral disc chemonucleolysis.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Myelography; Preoperative Care; Tomography, X-Ray Computed | 1986 |
[Doctor, I have a hernia; can I get a shot?].
Topics: Adolescent; Adult; Chymopapain; Diagnosis, Differential; Humans; Intervertebral Disc Displacement; Middle Aged; Prospective Studies; Spinal Diseases | 1986 |
[Chemonucleolysis in the treatment of lumbar nucleus pulposus hernia in young patients].
Topics: Adolescent; Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Radiography | 1986 |
[Treatment of disk sciatica by chemonucleolysis. Apropos of 166 cases].
Topics: Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica | 1986 |
Nerve root cut-off on metrizamide-enhanced computerized tomography.
Topics: Adult; Athletic Injuries; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Lumbosacral Region; Male; Metrizamide; Middle Aged; Myelography; Nerve Compression Syndromes; Radiographic Image Enhancement; Spinal Nerve Roots; Tomography, X-Ray Computed | 1986 |
Chymopapain in perspective.
Topics: Chymopapain; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Time Factors | 1986 |
Clinical studies of chemonucleolysis patients with ten- to twenty-year follow-up evaluation.
Topics: Activities of Daily Living; Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Pain; Time Factors | 1986 |
Eight- to 13-year follow-up evaluation of chemonucleolysis patients.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Myelography; Time Factors | 1986 |
Computed tomography (CT) analysis of the effects of chemonucleolysis.
Topics: Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Time Factors; Tomography, X-Ray Computed | 1986 |
Four brief reports on long-term results of intradiscal chymopapain.
Topics: Chymopapain; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Prospective Studies; Surveys and Questionnaires; Time Factors | 1986 |
The long-term results of chymopapain. Ten-year follow-up of 268 patients after chemonucleolysis.
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Myelography; Occupations; Physical Examination; Time Factors | 1986 |
Chemonucleolysis versus open discectomy. A ten-year follow-up study.
Topics: Adult; Chymopapain; Consumer Behavior; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Recurrence; Retrospective Studies; Surveys and Questionnaires; Time Factors; Work Schedule Tolerance | 1986 |
Chemonucleolysis. A ten-year retrospective study.
Topics: Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Radiography; Retrospective Studies; Surveys and Questionnaires; Time Factors | 1986 |
Long-term results of chymopapain injections.
Topics: Chymopapain; Consumer Behavior; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Time Factors | 1986 |
Discography: an element of decision. Surgery versus chemonucleolysis.
Topics: Adolescent; Adult; Aged; Chymopapain; Contrast Media; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Myelography; Pain; Preoperative Care; Tomography, X-Ray Computed | 1986 |
The long-term results of chymopapain chemonucleolysis for lumbar disc disease. Ten-year follow-up results in 268 patients injected at the Mayo Clinic.
Topics: Adult; Chymopapain; Employment; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male; Outcome and Process Assessment, Health Care; Postoperative Complications; Spinal Diseases | 1986 |
Intervertebral disc infection after lumbar chemonucleolysis: report of a case.
Topics: Blood Sedimentation; Chymopapain; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Leukocyte Count; Middle Aged; Myelography; Spinal Diseases; Staphylococcal Infections; Staphylococcus epidermidis; Tomography, X-Ray Computed | 1986 |
The honeymoon is over: spinal surgeons begin to divorce themselves from chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Laminectomy | 1986 |
Mechanism of action of intradiscal chymopapain in the treatment of sciatica: a clinical, biochemical, and radiological study.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Glycosaminoglycans; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica; Tomography, X-Ray Computed | 1986 |
Different operative possibilities for treatment of lumbar disc herniations--how to choose the best method for the individual patient.
Topics: Chymopapain; Humans; Injections; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Microsurgery; Postoperative Complications; Prognosis; Sciatica; Spinal Stenosis | 1986 |
Chemonucleolysis: a note of caution.
Topics: Chymopapain; Costs and Cost Analysis; Humans; Intervertebral Disc Displacement; Surgical Procedures, Operative | 1986 |
Chemonucleolysis. The relationship of the physical findings, discography, and myelography to the clinical result.
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Myelography; Physical Examination | 1986 |
Roentgenographic changes in 188 patients 10-20 years after discography and chemonucleolysis.
Topics: Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Radiography; Sciatica; Time Factors | 1986 |
[Cause of failure of nucleolysis and results of surgery].
Topics: Adolescent; Adult; Chymopapain; Diagnosis, Differential; Diagnostic Errors; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Recurrence; Spinal Stenosis | 1986 |
Percutaneous nucleotomy. An alternative to spinal surgery.
Topics: Adult; Aged; Catheterization; Chymopapain; Evaluation Studies as Topic; Female; Humans; Intervertebral Disc Displacement; Laminectomy; Male; Methods; Middle Aged; Postoperative Care; Reoperation | 1986 |
The effects of chymopapain on prolapsed human intervertebral disc. A clinical and correlative histochemical study.
Topics: Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Prolapse; Tomography, X-Ray Computed | 1986 |
The changes in the intervertebral disc after chemonucleolysis demonstrated by magnetic resonance imaging.
Topics: Acute Disease; Adolescent; Adult; Chymopapain; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Magnetic Resonance Spectroscopy; Male; Prospective Studies; Sciatica; Time Factors | 1986 |
[Significance of diskography and contrast medium/enzyme interaction].
Topics: Chymopapain; Extravasation of Diagnostic and Therapeutic Materials; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Iohexol; Lumbar Vertebrae; Metrizamide; Radiography | 1986 |
[Anesthesia procedures and perioperative patient monitoring in chemonucleolysis].
Topics: Anesthesia; Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Premedication | 1986 |
Chemonucleolysis. Current status and future outlook.
Topics: Anesthesia; Chymopapain; Dose-Response Relationship, Drug; Forecasting; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae | 1986 |
The biochemistry of the action of chymopapain in relief of sciatica.
Topics: Cartilage; Chromatography, Ion Exchange; Chymopapain; Cysteine; Glycosaminoglycans; Humans; Hydrogen-Ion Concentration; Intervertebral Disc Displacement; Proteoglycans; Sciatica | 1986 |
In defense of chemonucleolysis.
Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Radiography | 1986 |
[Chemonucleolysis in the treatment of surgical sciatica].
Topics: Adolescent; Adult; Aged; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Length of Stay; Lumbar Vertebrae; Male; Microsurgery; Middle Aged; Sacrum; Sciatica | 1985 |
[Surgical findings and results after failure of lumbar chemonucleolysis. 72 cases].
Topics: Adult; Aged; Chymopapain; Female; Humans; Inflammation; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Pain; Spinal Nerve Roots; Spinal Stenosis | 1985 |
Computerized axial tomography in the diagnosis of lumbar disc hernia.
Topics: Chymopapain; Combined Modality Therapy; Humans; Injections, Spinal; Intervertebral Disc Displacement; Lumbar Vertebrae; Methylprednisolone; Recurrence; Tomography, X-Ray Computed | 1985 |
Computed tomography and chymopapain chemonucleolysis: preliminary findings.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Tomography, X-Ray Computed | 1985 |
Chemonucleolysis failures treated by PLIF.
Topics: Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Joint Instability; Lumbar Vertebrae; Male; Postoperative Complications; Radiography; Spinal Fusion | 1985 |
Paraplegia following chymopapain injection. A case report.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Paraplegia; Tomography, X-Ray Computed | 1985 |
Hemorrhagic complications after the lumbar injection of chymopapain.
Topics: Adult; Arachnoiditis; Cerebral Hemorrhage; Chymopapain; Diatrizoate Meglumine; Drug Interactions; Endopeptidases; Hemorrhage; Humans; Intervertebral Disc Displacement; Iothalamate Meglumine; Male; Metrizamide; Spinal Cord Diseases; Subarachnoid Hemorrhage | 1985 |
Recent experience with chemonucleolysis: community standards and factors affecting outcome.
Topics: Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Male; Middle Aged | 1985 |
Treatment of intervertebral disc prolapse by intradiscal injection of chymopapain.
Topics: Anaphylaxis; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Recurrence | 1985 |
Efficacy of chymopapain chemonucleolysis. A long-term review of 105 patients.
Topics: Adolescent; Adult; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Outcome and Process Assessment, Health Care; Surveys and Questionnaires | 1985 |
[Chymopapain allergy. Diagnostic value of a skin test before and after chemonucleolysis].
Topics: Adult; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Iopamidol; Iothalamic Acid; Male; Skin Tests; Time Factors | 1985 |
The age-old back problem: new fad; same fallacies.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement | 1985 |
Anatomical basis of intervertebral disc puncture with chemonucleolysis.
Topics: Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Spinal Nerves; Spinal Puncture; Spine; Tomography, X-Ray Computed | 1985 |
Chemonucleolysis in the treatment of lumbar disc disease.
Topics: Adolescent; Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Myelography; Sciatica; Tomography, X-Ray Computed | 1985 |
Urological complications following chemonucleolysis.
Topics: Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Hyperesthesia; Hypesthesia; Intervertebral Disc Displacement; Male; Middle Aged; Penile Diseases; Perineum; Urinary Bladder, Neurogenic | 1985 |
Microdiscectomy versus chemonucleolysis.
Topics: Adolescent; Adult; Aged; Chymopapain; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Microsurgery; Middle Aged; Postoperative Complications; Sciatica | 1985 |
The comparative biomechanical, histologic, and radiographic analysis of canine lumbar discs treated by surgical excision or chemonucleolysis.
Topics: Animals; Chymopapain; Dogs; Endopeptidases; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Movement; Radiography; Time Factors | 1985 |
Reactivity of IgE and IgG serum levels to chymopapain after chemonucleolysis.
Topics: Antigen-Antibody Reactions; Binding Sites, Antibody; Binding, Competitive; Chymopapain; Endopeptidases; Female; Humans; Immunoglobulin E; Immunoglobulin G; Intervertebral Disc Displacement; Male; Radioallergosorbent Test | 1985 |
Skin testing in chymopapain anaphylaxis.
Topics: Adult; Anaphylaxis; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Intradermal Tests; Male; Radioallergosorbent Test; Skin Tests | 1985 |
A case report on nonresolving conservative care of low back pain and sciatic radicular syndrome.
Topics: Adult; Chiropractic; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Radiography; Sciatica | 1985 |
[Allergy to chymopapain: value of predictive tests before chemonucleolysis].
Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Risk; Skin Tests | 1985 |
Chymopapain chemonucleolysis: correlation of diagnostic radiographic factors and clinical outcome.
Topics: Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Prognosis; Radiography | 1985 |
Chymopapain chemonucleolysis: CT changes after treatment.
Topics: Adult; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Tomography, X-Ray Computed | 1985 |
Prospective evaluation of chymopapain sensitivity in patients undergoing chemonucleolysis.
Topics: Anaphylaxis; Chymopapain; Cross Reactions; Endopeptidases; Evaluation Studies as Topic; Humans; Immunoglobulin E; Intervertebral Disc Displacement; Radioallergosorbent Test | 1985 |
Chymopapain and prolapsed disc.
Topics: Adult; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male | 1985 |
Chemonucleolysis: an evolving concept and clinical review.
Topics: Adult; Aged; Chymopapain; Endopeptidases; Female; Humans; Injections; Intervertebral Disc Displacement; Male; Methods; Middle Aged; Radiography | 1985 |
Chemonucleolysis--unexpected new horizons for research.
Topics: Adolescent; Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement | 1985 |
Cost effectiveness of chemonucleolysis versus laminectomy in the treatment of herniated nucleus pulposus.
Topics: Adult; Aged; Chymopapain; Cost-Benefit Analysis; Female; Hospitalization; Humans; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Reoperation | 1985 |
The treatment of herniated disc in Australia. Costs and benefits of intradiscal injection of chymopapain and surgery.
Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Chymopapain; Cost-Benefit Analysis; Female; Humans; Infant; Infant, Newborn; Intervertebral Disc Displacement; Male; Methods; Middle Aged | 1985 |
Efficacy of chymopapain chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement | 1986 |
Skin testing for chymopapain allergy in chemonucleolysis.
Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Female; Humans; Intervertebral Disc Displacement; Male; Preoperative Care; Skin Tests | 1986 |
Lumbar discography: redefining its role with intradiscal therapy.
Topics: Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Radiography | 1986 |
The use of mechanical etiology to determine the efficacy of active intervention in single joint lumbar intervertebral joint problems. Surgery and chemonucleolysis compared: a prospective study.
Topics: Biomechanical Phenomena; Chymopapain; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Models, Biological; Prospective Studies | 1985 |
Open letter to surgeons performing chemonucleolysis (from a surgeon performing chemonucleolysis)
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Surgical Procedures, Operative | 1985 |
Skin tests for chymopapain allergy.
Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Displacement; Premedication; Skin Tests | 1985 |
Efficacy and safety of chymopapain versus laminectomy.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Laminectomy | 1985 |
Pretreatment serum levels of IgE to chymopapain in reactive patients.
Topics: Chymopapain; Humans; Hypersensitivity; Immunoglobulin E; Intervertebral Disc Displacement; Radioallergosorbent Test | 1985 |
A comparison of discectomy and chemonucleolysis.
Topics: Chymopapain; Costs and Cost Analysis; Epidemiologic Methods; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Length of Stay; Reoperation; Sciatica | 1985 |
Chemonucleolysis for herniated nucleus pulposus in adolescents.
Topics: Adolescent; Adult; Age Factors; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Neuroleptanalgesia | 1985 |
Microdiscectomy vs. chemonucleolysis.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement; Methylprednisolone; Methylprednisolone Acetate; Pain | 1985 |
Chymopapain for intervertebral disc herniation.
Topics: Chymopapain; Humans; Intervertebral Disc Displacement | 1985 |
Surgical findings and results of surgery after failure of chemonucleolysis.
Topics: Adolescent; Adult; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged | 1985 |