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1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Back Pain

1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt has been researched along with Back Pain in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199037 (78.72)18.7374
1990's9 (19.15)18.2507
2000's0 (0.00)29.6817
2010's1 (2.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eastmond, CJ; Rithchie, IK; Sabboubeh, AF; Vavdha, M; Wardlaw, D1
Weir, B1
Onofrio, BM1
Cecile, JP; Deschamps, C; Makart, A1
Fager, CA1
Flor, H; Turk, DC1
Brock, M; Curio, G; Görge, HH1
Burton, CV1
Porter, RW; Ralston, SH1
Konings, JG1
Bradbury, N; Mulholland, RC; Wilson, LF1
Bartels, EM; Fairbank, JC; Urban, JP; Winlove, CP1
Sussman, BJ1
Rocchio, PD; Wiltse, LL1
Sullivan, M1
Daughety, JS; Herrick, RB; Hoover, BB1
DiMaio, VJ1
Graham, CE2
McCulloch, JA1
Halliday, WR1
Hadler, NM; Quinet, RJ1
Kääpä, E; Vanharanta, H1
Abdel-Salam, A; Cleary, J; Eyres, KS1
Cleary, JE; Eyres, KS; Salam, A1
Antoniou, J; Hadjipavlou, A; Lander, P1
Bouillet, R1
Schretlen, E; Spring, M1
Dyck, P1
Nachemson, AL1
Hejna, W; Lehmann, T; McNeill, T; Spratt, KF; Weinstein, J1
Shields, CB; Williams, PE1
Ortiz, JE; Rojas, JE1
Amor, B; Chevrot, A; Feldman, J; Godefroy, D; Horreard, P; Menkès, CJ; Pallardy, G; Zenny, JC1
Parise, M1
Bradford, DS; Gotfried, Y; Oegema, TR1
Crews, DA; Warfield, CA1
Amor, B; Chevrot, A; Cormier, C; Menkès, CJ1
Arrault, I; Benoist, M; Bourgeois, P; Caroit, M; Dufour, D; Jorgensen, C; Rouaud, JP; Roucoulès, J; Ryckewaert, A; Ségala, L1
Belmatoug, N; Benoist, M; Binoche, T; Bourgeois, P; Busson, G; Folinais, D; Frot, B; Lassale, P; Montagner, C; Palazzo, E1
Blakley, JB; Daffner, RH; Deeb, ZL; Hryshko, FG; Lupetin, AR; Schimel, S1
Bellows, JG; McCarthy, MM1
Maslanka, T; Sideranko, C1
Brown, MD; Tompkins, JS1
Burton, CV; Heithoff, KB1
Nachemson, A1

Reviews

9 review(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Back Pain

ArticleYear
Etiological theories and treatments for chronic back pain. I. Somatic models and interventions.
    Pain, 1984, Volume: 19, Issue:2

    Topics: Adult; Antidepressive Agents; Back Pain; Chymopapain; Female; Humans; Male; Manipulation, Orthopedic; Middle Aged; Muscle Relaxants, Central; Muscular Diseases; Narcotics; Occupational Diseases; Orthotic Devices; Osteoarthritis; Physical Therapy Modalities; Spinal Diseases; Spinal Injuries; Spondylitis; Spondylolisthesis; Steroids; Traction; Transcutaneous Electric Nerve Stimulation

1984
[Chemonucleolysis as an alternative to open surgical treatment of lumbar herniated disk].
    Deutsche medizinische Wochenschrift (1946), 1984, Jan-13, Volume: 109, Issue:2

    Topics: Aftercare; Anesthesia, General; Anesthesia, Local; Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Microbial Collagenase; Spinal Puncture

1984
Pharmacological management of back pain syndromes.
    Drugs, 1994, Volume: 48, Issue:2

    Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Calcitonin; Central Nervous System Agents; Chymopapain; Diagnosis, Differential; Diphosphonates; Humans; Pain Measurement

1994
Chymopapain chemonucleolysis.
    Acta orthopaedica Scandinavica. Supplementum, 1993, Volume: 251

    Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Sciatica

1993
Inadequacies and hazards of chymopapain injections as treatment for intervertebral disc disease.
    Journal of neurosurgery, 1975, Volume: 42, Issue:4

    Topics: Adult; Animals; Arachnoiditis; Back Pain; Cats; Cerebrovascular Disorders; Chymopapain; Dogs; Drug Hypersensitivity; Endopeptidases; Headache; Hemiplegia; Humans; Inflammation; Intervertebral Disc; Intervertebral Disc Displacement; Paraplegia; Rabbits; Sensation; Spasm; Subarachnoid Hemorrhage; Syndrome; Urinary Bladder, Neurogenic

1975
Diagnosis and treatment of backache.
    Seminars in arthritis and rheumatism, 1979, Volume: 8, Issue:4

    Topics: Acute Disease; Adrenal Cortex Hormones; Back Pain; Braces; Chymopapain; Clinical Trials as Topic; Emergencies; Exercise Therapy; Humans; Injections; Intervertebral Disc; Manipulation, Orthopedic; Muscle Relaxants, Central; Physical Therapy Modalities; Radiography; Spinal Diseases; Traction

1979
[Intervertebral disk degeneration--a central cause of back problems].
    Duodecim; laaketieteellinen aikakauskirja, 1991, Volume: 107, Issue:19

    Topics: Animals; Back Pain; Chymopapain; Dogs; Exercise; Humans; Intervertebral Disc; Proteoglycans; Rabbits; Rats; Regeneration

1991
Advances in low-back pain.
    Clinical orthopaedics and related research, 1985, Issue:200

    Topics: Animals; Back Pain; Biomechanical Phenomena; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Movement; Pressure; Rest; Sciatica; Spinal Diseases; Spondylolisthesis; Traction

1985
Recent advances in the treatment of low back pain.
    International orthopaedics, 1985, Volume: 9, Issue:1

    Topics: Animals; Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Movement; Physical Exertion; Posture; Pressure; Sciatica; Stress, Mechanical; Stress, Psychological; Traction

1985

Trials

6 trial(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Back Pain

ArticleYear
Prospective randomized trial of chemonucleolysis compared with surgery for soft disc herniation with 1-year, intermediate, and long-term outcome: part I: the clinical outcome.
    Spine, 2013, Aug-01, Volume: 38, Issue:17

    Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Diskectomy; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Leg; Lumbar Vertebrae; Male; Middle Aged; Pain; Postoperative Complications; Prospective Studies; Sacrum; Surveys and Questionnaires; Time Factors; Treatment Outcome; Young Adult

2013
Adolescent disc protrusions. A long-term follow-up of surgery compared to chymopapain.
    Spine, 1996, Feb-01, Volume: 21, Issue:3

    Topics: Activities of Daily Living; Adolescent; Adult; Back Pain; Chymopapain; Disability Evaluation; Employment; Female; Follow-Up Studies; Humans; Intervertebral Disc Displacement; Length of Stay; Male; Pain; Pain Measurement; Treatment Outcome

1996
Chemonucleolysis: a double blind study comparing chemonucleolysis with intra discal hydrocortisone: in the treatment of backache and sciatica.
    Clinical orthopaedics and related research, 1976, Issue:117

    Topics: Adult; Anaphylaxis; Back Pain; Chymopapain; Clinical Trials as Topic; Endopeptidases; Female; Humans; Hydrocortisone; Injections; Male; Middle Aged; Sciatica

1976
Diagnosis and treatment of backache.
    Seminars in arthritis and rheumatism, 1979, Volume: 8, Issue:4

    Topics: Acute Disease; Adrenal Cortex Hormones; Back Pain; Braces; Chymopapain; Clinical Trials as Topic; Emergencies; Exercise Therapy; Humans; Injections; Intervertebral Disc; Manipulation, Orthopedic; Muscle Relaxants, Central; Physical Therapy Modalities; Radiography; Spinal Diseases; Traction

1979
[Double-blind study of the treatment of disc lumbosciatica by chemonucleolysis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1986, Volume: 53, Issue:3

    Topics: Adult; Aged; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Sciatica; Time Factors

1986
[Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months].
    Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:10

    Topics: Adult; Back Pain; Chymopapain; Double-Blind Method; Female; Humans; Injections, Spinal; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation; Sciatica; Triamcinolone Acetonide

1988

Other Studies

33 other study(ies) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Back Pain

ArticleYear
Lumbar discectomy or chemonucleolysis: pros and cons.
    Surgery annual, 1982, Volume: 14

    Topics: Back Pain; Chymopapain; Endopeptidases; Evaluation Studies as Topic; Humans; Injections, Spinal; Intervertebral Disc; Intervertebral Disc Displacement; Prospective Studies

1982
Chemonucleolysis--past and present.
    Mayo Clinic proceedings, 1983, Volume: 58, Issue:3

    Topics: Back Pain; Chymopapain; Endopeptidases; Humans; Legislation, Drug; United States; United States Food and Drug Administration

1983
[Chemonucleolysis].
    Journal belge de radiologie, 1982, Volume: 65, Issue:5

    Topics: Anesthesia, Local; Back Pain; Chymopapain; Endopeptidases; Follow-Up Studies; Humans; Intervertebral Disc; Sciatica

1982
The age-old back problem. New fad, same fallacies.
    Spine, 1984, Volume: 9, Issue:3

    Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Laminectomy; Prognosis; Sciatica; Spinal Fusion

1984
Conservative management of low back pain.
    Postgraduate medicine, 1981, Volume: 70, Issue:5

    Topics: Back Pain; Bed Rest; Chymopapain; Humans; Intervertebral Disc Displacement; Nerve Block; Posture; Spinal Fusion; Spine; Stress, Mechanical; Traction

1981
Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back pain.
    Spine, 1998, Jan-01, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc; Lactic Acid; Male; Microelectrodes; Middle Aged; Oxygen; Radiography; Scoliosis; Water

1998
Preoperative psychological tests as predictors of success of chemonucleolysis in the treatment of the low-back syndrome.
    The Journal of bone and joint surgery. American volume, 1975, Volume: 57, Issue:4

    Topics: Adult; Back Pain; Chymopapain; Cornell Medical Index; Endopeptidases; Female; Humans; Hypochondriasis; Hysteria; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Male; Mental Processes; MMPI; Psychological Tests; Psychophysiologic Disorders; Retrospective Studies; Syndrome; Wechsler Scales

1975
Chemonucleolysis.
    Proceedings of the Royal Society of Medicine, 1975, Volume: 68, Issue:8

    Topics: Adult; Back Pain; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Hypersensitivity, Delayed; Injections; Intervertebral Disc; Male; Middle Aged; Myelography

1975
Clinical and electromyographic evaluation after chemonucleolysis for lumbar disk disease.
    Southern medical journal, 1975, Volume: 68, Issue:12

    Topics: Back Pain; Chymopapain; Electromyography; Endopeptidases; Evaluation Studies as Topic; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis; Sciatica

1975
Two anaphylactic deaths after chemonucleolysis.
    Journal of forensic sciences, 1976, Volume: 21, Issue:1

    Topics: Adult; Anaphylaxis; Autopsy; Back Pain; Chymopapain; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Middle Aged

1976
Chemonucleolysis.
    The Journal of bone and joint surgery. British volume, 1977, Volume: 59, Issue:1

    Topics: Adult; Back Pain; Chymopapain; Dermatitis, Contact; Endopeptidases; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Postoperative Care; Prospective Studies; Recurrence; Spinal Diseases

1977
Chymopapain and chemonucleolysis.
    JAMA, 1978, Dec-01, Volume: 240, Issue:23

    Topics: Back Pain; Chronic Disease; Chymopapain; Endopeptidases; Humans; United States; United States Food and Drug Administration

1978
A new paradiscal injection technique for the relief of back spasm after chemonucleolysis.
    British journal of rheumatology, 1992, Volume: 31, Issue:7

    Topics: Adult; Back; Back Pain; Bupivacaine; Chymopapain; Female; Humans; Injections; Intervertebral Disc; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Muscle Spasticity

1992
A new paradiscal injection technique for the relief of back spasm after chemonucleolysis.
    Spine, 1992, Volume: 17, Issue:7

    Topics: Back Pain; Bupivacaine; Chymopapain; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Postoperative Complications

1992
The effect of chymopapain on low back pain.
    Orthopaedic review, 1992, Volume: 21, Issue:6

    Topics: Adult; Back Pain; Chymopapain; Female; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Tomography, X-Ray Computed

1992
Treatment of sciatica. A comparative survey of complications of surgical treatment and nucleolysis with chymopapain.
    Clinical orthopaedics and related research, 1990, Issue:251

    Topics: Adolescent; Adult; Back Pain; Chymopapain; Discitis; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Peripheral Nervous System Diseases; Postoperative Complications; Pulmonary Embolism; Sciatica; Thrombophlebitis

1990
Acute disc: trends in treatment.
    The Canadian nurse, 1989, Volume: 85, Issue:7

    Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement

1989
Paraplegia following chemonucleolysis. A case report and discussion of neurotoxicity.
    Spine, 1985, Volume: 10, Issue:4

    Topics: Adult; Back Pain; Cauda Equina; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Paraplegia; Subarachnoid Hemorrhage

1985
Lumbar disc herniation. A comparison of the results of chemonucleolysis and open discectomy after ten years.
    The Journal of bone and joint surgery. American volume, 1986, Volume: 68, Issue:1

    Topics: Adult; Back Pain; Chymopapain; Consumer Behavior; Female; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Retrospective Studies; Spinal Fusion; Surveys and Questionnaires; Time Factors; Work Capacity Evaluation

1986
Low back pain.
    American family physician, 1986, Volume: 33, Issue:3

    Topics: Arthritis; Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Physical Examination; Psychophysiologic Disorders; Rest; Spinal Cord Neoplasms; Sprains and Strains; Tomography, X-Ray Computed

1986
Nonresolving conservative care of low back pain.
    Journal of manipulative and physiological therapeutics, 1986, Volume: 9, Issue:1

    Topics: Back Pain; Chiropractic; Chymopapain; Humans

1986
Low back pain, sciatica and chemonucleolysis: a community hospital experience.
    The Journal of the Florida Medical Association, 1986, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Aged; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Sciatica

1986
[Nursing care report. Apropos of a case of lumbosciatica treated with chemonucleolysis].
    Soins; la revue de reference infirmiere, 1986, Issue:473

    Topics: Adult; Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Male

1986
Facet joint changes after chemonucleolysis-induced disc space narrowing.
    Spine, 1986, Volume: 11, Issue:9

    Topics: Animals; Back Pain; Cartilage, Articular; Chymopapain; Disease Models, Animal; Dogs; Hexuronic Acids; Intervertebral Disc; Intervertebral Disc Chemolysis; Ligaments, Articular; Lumbar Vertebrae; Proteoglycans; Radiography

1986
Epidural steroid injection as a predictor of surgical outcome.
    Surgery, gynecology & obstetrics, 1987, Volume: 164, Issue:5

    Topics: Back Pain; Chymopapain; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Lidocaine; Methylprednisolone; Methylprednisolone Acetate; Prognosis; Radiculopathy

1987
[Long-term results of chymopapain nucleolysis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:2

    Topics: Adult; Back Pain; Chymopapain; Female; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Recurrence; Retrospective Studies; Sciatica

1988
[Disk collapse after nucleolysis with chymopapain].
    Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:7

    Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Lumbar Vertebrae; Recurrence; Sacrum; Spinal Diseases

1988
Intervertebral disk-space infection after chymopapain injection.
    AJR. American journal of roentgenology, 1985, Volume: 144, Issue:4

    Topics: Adult; Back Pain; Chymopapain; Endopeptidases; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbosacral Region; Male; Middle Aged; Spinal Diseases; Staphylococcal Infections; Tomography, X-Ray Computed

1985
Backache: a second look.
    Comprehensive therapy, 1985, Volume: 11, Issue:3

    Topics: Back Pain; Biomechanical Phenomena; Chymopapain; Humans; Physical and Rehabilitation Medicine; Traction

1985
Chemonucleolysis for sciatica and low back pain.
    The Medical journal of Australia, 1985, Apr-15, Volume: 142, Issue:8

    Topics: Anaphylaxis; Back Pain; Chymopapain; Endopeptidases; Humans; Injections; Intervertebral Disc; Intervertebral Disc Displacement; Postoperative Care; Sciatica

1985
An alternative to back surgery--for some patients.
    RN, 1985, Volume: 48, Issue:5

    Topics: Back Pain; Chymopapain; Humans; Intervertebral Disc Displacement; Male; Postoperative Care; Sciatica

1985
Dissolving a lifetime of lower back pain with chemonucleolysis.
    Nursing, 1985, Volume: 15, Issue:7

    Topics: Back Pain; Chymopapain; Endopeptidases; Humans; Intervertebral Disc Displacement; Male; Middle Aged

1985
CT evaluation of the failed back surgery syndrome.
    The Orthopedic clinics of North America, 1985, Volume: 16, Issue:3

    Topics: Arachnoiditis; Back Pain; Chymopapain; Humans; Laminectomy; Metrizamide; Patient Care Planning; Postoperative Complications; Tomography, X-Ray Computed

1985