1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Allergy, Drug

1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt has been researched along with Allergy, Drug in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (79.07)	18.7374
1990's	9 (20.93)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Musolf, JM	1
Bagshaw, RJ; Bloom, MJ; Bruno, LA; Cohen, AM; Domino, K; Lupo, SE; Smith, DS; Star, AM	1
Grammer, LC; Patterson, R; Ricketti, AJ; Schafer, MF	1
Grammer, LC; Patterson, R	1
Arndt, L; Calenoff, E; Crispin, B; Jones, R; Rock, H; Sun, J; Tsay, YG	1
Arndt, L; Calenoff, E; Crispin, B; Jones, R; McDermott, D; Stern, I; Sun, J; Tsay, YG	1
Baumann, A; Feldmann, L; Kanny, G; Moneret-Vautrin, DA; Pere, P; Roland, J	1
Laxenaire, MC; Moneret-Vautrin, DA	1
Knighton, R; Roulhac, G; Watts, C	1
Sussman, BJ	1
Sullivan, M	1
Kaplan, R	1
Clark, K; Hutchison, G; Stern, J; Watts, C	1
Goldstein, G; Watts, C; Williams, OB	1
Brown, MD; Kitchel, SH	1
Candito, M; Grimaud, D; Lapalus, P; Occelli, G; Philip, F; Raucoules, M	1
Cisteró, A; García-Ortega, P; Ramírez Ferreiras, W; Sancho, A; Urías, S	1
Baligadoo, S; Dry, J; Guérin, B; Leynadier, F	1
Bouillet, R	2
Ghosh, P; Melrose, J; Taylor, TK	1
Nitzschke, E; Schleberger, R; Wahn, U	1
Cornaille, G; Dry, J; Guérin, B; Leynadier, F; Menkes, CJ	1
Brock, M; Mayer, HM; Piepenbrock, S; Schäffer, J	1
Dabezies, EJ; Langford, K; Morris, J; Shields, CB; Wilkinson, HA	1
Bock-Lamberlin, PR; Rose, FW; Schwonbeck, M	1
Adkinson, NF; Anderson, JA	1
Bernstein, D; Bernstein, IL; Cogen, F; Dolovich, J; Grammer, LC; Gutt, L; Schafer, M; Schatz, M; Shaughnessy, JJ; Zeiger, R	1
Mayer, HM	1
Bernstein, DI; Bernstein, IL	1
Hewitt, BE	1
Berezowskyj, J; Schweigel, JF	1
Castagnera, L; Lavignolle, B; Macouillard, G; Maurette, P	1
McCulloch, JA	1
Bachmann, B; Biscoping, J; Hempelmann, G; Müller, U	1
Shields, CB	1
Battit, GE	1
Brock, M; Mayer, HM	1
Berkson, B; Firfer, R; Primack, ML; Zakhary, MG	1
Benoist, M; Croizier, A; Guéant, JL; Laxenaire, MC; Moneret-Vautrin, DA	1
Brock, M; Kaden, B; Mayer, HM; Wehr, M	1
Canham, WD; Dolovich, J; McCulloch, JA	1

Reviews

6 review(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Allergy, Drug

Article	Year
Chymopapain treatment of intervertebral disc disease. Journal of neurosurgery, 1975, Volume: 42, Issue:4 Topics: Anaphylaxis; Animals; Arachnoiditis; Catalysis; Cats; Causalgia; Chemical Phenomena; Chemistry; Chymopapain; Diagnostic Errors; Dogs; Drug Hypersensitivity; Endopeptidases; Follow-Up Studies; Glycosaminoglycans; Guinea Pigs; Humans; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Intervertebral Disc; Intervertebral Disc Displacement; Rabbits; Spinal Cord Diseases; Time Factors	1975
Inadequacies and hazards of chymopapain injections as treatment for intervertebral disc disease. Journal of neurosurgery, 1975, Volume: 42, Issue:4 Topics: Adult; Animals; Arachnoiditis; Back Pain; Cats; Cerebrovascular Disorders; Chymopapain; Dogs; Drug Hypersensitivity; Endopeptidases; Headache; Hemiplegia; Humans; Inflammation; Intervertebral Disc; Intervertebral Disc Displacement; Paraplegia; Rabbits; Sensation; Spasm; Subarachnoid Hemorrhage; Syndrome; Urinary Bladder, Neurogenic	1975
Complications of chemonucleolysis. Clinical orthopaedics and related research, 1992, Issue:284 Topics: Anaphylaxis; Cerebral Hemorrhage; Chymopapain; Discitis; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Personality; Seizures	1992
[Changes in plasma histamine and catecholamines levels after injection of chymopapain in chemonucleolysis]. Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:6 Topics: Adult; Basophil Degranulation Test; Catecholamines; Chymopapain; Drug Hypersensitivity; Female; Histamine; Humans; Hydroxyzine; Intervertebral Disc Chemolysis; Male; Middle Aged; Premedication; Prospective Studies; Radioallergosorbent Test; Skin Tests; Tranexamic Acid	1991
Allergic reactions to drugs and biologic agents. JAMA, 1987, Nov-27, Volume: 258, Issue:20 Topics: Anesthetics; Anti-Bacterial Agents; Aspirin; Biological Products; Chymopapain; Contrast Media; Drug Hypersensitivity; Humans; Insulin; Lactams; Vaccines	1987
Chymopapain induced allergic reactions. Clinical reviews in allergy, 1986, Volume: 4, Issue:2 Topics: Anaphylaxis; Antibody Formation; Chymopapain; Cross Reactions; Drug Hypersensitivity; False Negative Reactions; Fluorescent Antibody Technique; Follow-Up Studies; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunoglobulin E; Injections; Lumbar Vertebrae; Papain; Radioallergosorbent Test; Skin Tests	1986

Trials

1 trial(s) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Allergy, Drug

Article	Year
Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study. Spine, 1988, Volume: 13, Issue:5 Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Double-Blind Method; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Middle Aged; Muscular Diseases; Random Allocation; Sciatica; Spasm; Spine	1988

Article

Year

Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study.

Spine, 1988, Volume: 13, Issue:5

Topics: Adolescent; Adult; Aged; Anaphylaxis; Chymopapain; Double-Blind Method; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Middle Aged; Muscular Diseases; Random Allocation; Sciatica; Spasm; Spine

1988

Other Studies

36 other study(ies) available for 1,2-dihydroxybenzene-3,5-disulfonic acid disodium salt and Allergy, Drug

Article	Year
Chemonucleolysis. A new approach for patients with herniated intervertebral disks. The American journal of nursing, 1983, Volume: 83, Issue:6 Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Injections; Intervertebral Disc Displacement; Male; Nursing Care	1983
Sudden hypotension with a test dose of chymopapain. Anesthesia and analgesia, 1984, Volume: 63, Issue:5 Topics: Adult; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Hypersensitivity, Immediate; Hypotension; Intervertebral Disc Displacement; Intraoperative Period; Lumbar Vertebrae; Male; Premedication; Urticaria	1984
Chymopapain allergy: case reports and identification of patients at risk for chymopapain anaphylaxis. Clinical orthopaedics and related research, 1984, Issue:188 Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Drug Industry; Endopeptidases; Female; Humans; Immunoglobulin E; Injections; Intervertebral Disc; Male; Middle Aged; Occupational Diseases; Risk	1984
Proteins: chymopapain and insulin. The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:4 Pt 2 Topics: Adult; Aged; Anaphylaxis; Asthma; Chymopapain; Drug Hypersensitivity; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Female; Humans; Insulin; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests	1984
A preoperative chymopapain sensitivity test for chemonucleolysis candidates. Spine, 1984, Volume: 9, Issue:7 Topics: Antibody Specificity; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Immunoenzyme Techniques; Immunoglobulin E; Intervertebral Disc Displacement; Lumbar Vertebrae	1984
Chymopapain-induced hypersensitivity following chemonucleolysis. Spine, 1984, Volume: 9, Issue:7 Topics: Antibody Specificity; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Immunoenzyme Techniques; Immunoglobulin E; Intervertebral Disc Displacement	1984
Incidence and risk factors for latent sensitization to chymopapain: predictive skin-prick tests in 700 candidates for chemonucleolysis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:5 Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Factors; Skin Tests	1994
Concept and limitations of predictive tests in anaesthesiology. Annales francaises d'anesthesie et de reanimation, 1993, Volume: 12, Issue:2 Topics: Anaphylaxis; Anesthesia; Chymopapain; Drug Hypersensitivity; Humans; Neuromuscular Blocking Agents; Predictive Value of Tests; Risk	1993
Chemonucleolysis. Proceedings of the Royal Society of Medicine, 1975, Volume: 68, Issue:8 Topics: Adult; Back Pain; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Hypersensitivity, Delayed; Injections; Intervertebral Disc; Male; Middle Aged; Myelography	1975
Sensitivity reaction--chymopapain vs. radiographic dye. Anesthesiology, 1977, Volume: 47, Issue:4 Topics: Chymopapain; Diatrizoate; Diatrizoate Meglumine; Drug Hypersensitivity; Endopeptidases; Humans	1977
Comparison of intervertebral disc disease treatment by chymopapain injection and open surgery. Journal of neurosurgery, 1975, Volume: 42, Issue:4 Topics: Adult; Arachnoiditis; Causalgia; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Follow-Up Studies; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Male; Middle Aged; Postoperative Complications	1975
Sensitivity reactions to intradiscal injection of chymopapain during general anesthesia. Anesthesiology, 1976, Volume: 44, Issue:5 Topics: Adult; Aged; Anesthesia, Inhalation; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Halothane; Humans; Injections; Intervertebral Disc; Male; Middle Aged; Oxygen	1976
[Alternatives to chemonucleolysis]. Medicina clinica, 1991, Sep-21, Volume: 97, Issue:9 Topics: Administration, Topical; Anti-Inflammatory Agents; Chymopapain; Drug Hypersensitivity; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Time Factors; Triamcinolone Acetonide	1991
[Sensitization to chymopapain in patients treated with chemonucleolysis]. Medicina clinica, 1991, Mar-23, Volume: 96, Issue:11 Topics: Adult; Chymopapain; Drug Hypersensitivity; Humans; Immunoglobulin E; Intervertebral Disc Chemolysis; Middle Aged; Skin Tests	1991
[Relation of papaya ingestion and the presence of chymopapain-specific immunoglobulins E]. Presse medicale (Paris, France : 1983), 1990, Mar-10, Volume: 19, Issue:9 Topics: Adult; Chymopapain; Drug Hypersensitivity; Female; Fruit; Humans; Immunoglobulin E; Male	1990
Treatment of sciatica. A comparative survey of complications of surgical treatment and nucleolysis with chymopapain. Clinical orthopaedics and related research, 1990, Issue:251 Topics: Adolescent; Adult; Back Pain; Chymopapain; Discitis; Drug Hypersensitivity; Female; Humans; Incidence; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Male; Peripheral Nervous System Diseases; Postoperative Complications; Pulmonary Embolism; Sciatica; Thrombophlebitis	1990
Chemonucleolysis: a further look at a contentious issue. The Medical journal of Australia, 1990, Nov-19, Volume: 153, Issue:10 Topics: Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Proteoglycans	1990
[Immunologic methods of study for evaluating the risk of anaphylactic reactions in intradisk chymopapain injections]. Neurochirurgia, 1986, Volume: 29 Suppl 1 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Histamine Release; Humans; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Leukocytes; Patch Tests; Radioallergosorbent Test; Risk	1986
[Skin tests and chymopapain-specific immunoglobulins E after chemonucleolysis]. Presse medicale (Paris, France : 1983), 1987, May-16, Volume: 16, Issue:18 Topics: Adult; Aged; Chymopapain; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Intervertebral Disc Chemolysis; Male; Middle Aged; Radioallergosorbent Test; Risk; Skin Tests	1987
[Anesthesiologic aspects of chemonucleolysis in local anesthesia]. Anasthesie, Intensivtherapie, Notfallmedizin, 1985, Volume: 20, Issue:2 Topics: Adult; Anesthesia, Local; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Intervertebral Disc Displacement; Intradermal Tests; Lumbar Vertebrae; Microbial Collagenase; Risk	1985
[Chemonucleolysis--with extended indications. 4 years clinical experience]. Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1988, Volume: 126, Issue:6 Topics: Cauda Equina; Chymopapain; Combined Modality Therapy; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Lumbar Vertebrae; Prognosis	1988
Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. Clinical orthopaedics and related research, 1988, Issue:234 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Immunoglobulin G; Intervertebral Disc Chemolysis; Intradermal Tests; Skin Tests	1988
[Incidence and prevention of allergic reactions following chemonucleolysis with chymopapain]. Neurochirurgia, 1986, Volume: 29 Suppl 1 Topics: Anaphylaxis; Chymopapain; Cross-Sectional Studies; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Intradermal Tests; Patch Tests	1986
Sensitivity testing with the Chymo-FAST test. Neurochirurgia, 1986, Volume: 29 Suppl 1 Topics: Chymopapain; Drug Hypersensitivity; Fluorescent Antibody Technique; Humans; Immunoglobulin E; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement	1986
Repeat chymopapain injections. Results and complications. Spine, 1987, Volume: 12, Issue:8 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Edema; Female; Humans; Hypotension; Intervertebral Disc Chemolysis; Male	1987
[Detection of patients at risk of allergy to chymopapain before and after chemonucleolysis. Choice of preventive medication]. Acta orthopaedica Belgica, 1987, Volume: 53, Issue:2 Topics: Chymopapain; Drug Hypersensitivity; Female; Humans; Immunization; Intervertebral Disc Chemolysis; Male; Skin Tests	1987
Skin testing for Chymopapain sensitivity. Acta orthopaedica Belgica, 1987, Volume: 53, Issue:2 Topics: Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Skin Tests	1987
[Complication of disk nucleolysis with chymopapain]. Acta orthopaedica Belgica, 1987, Volume: 53, Issue:2 Topics: Adult; Chymopapain; Drug Hypersensitivity; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Intervertebral Disc; Intervertebral Disc Chemolysis; Male; Middle Aged; Nervous System Diseases; Sciatica; Spinal Diseases; Surveys and Questionnaires	1987
[Anesthesia procedures and perioperative patient monitoring in chemonucleolysis]. Neurochirurgia, 1986, Volume: 29 Suppl 1 Topics: Anesthesia; Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Premedication	1986
In defense of chemonucleolysis. Clinical neurosurgery, 1986, Volume: 33 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Follow-Up Studies; Humans; Intervertebral Disc Chemolysis; Intervertebral Disc Displacement; Laminectomy; Lumbar Vertebrae; Radiography	1986
Anaphylaxis associated with chymopapain injections. JAMA, 1985, Feb-15, Volume: 253, Issue:7 Topics: Anaphylaxis; Anesthesia; Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans	1985
[Chymopapain allergy. Diagnostic value of a skin test before and after chemonucleolysis]. Neurochirurgia, 1985, Volume: 28, Issue:2 Topics: Adult; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Iopamidol; Iothalamic Acid; Male; Skin Tests; Time Factors	1985
Urological complications following chemonucleolysis. The Journal of urology, 1985, Volume: 133, Issue:6 Topics: Chymopapain; Drug Hypersensitivity; Endopeptidases; Humans; Hyperesthesia; Hypesthesia; Intervertebral Disc Displacement; Male; Middle Aged; Penile Diseases; Perineum; Urinary Bladder, Neurogenic	1985
[Allergy to chymopapain: value of predictive tests before chemonucleolysis]. Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:3 Topics: Adult; Anaphylaxis; Chymopapain; Drug Hypersensitivity; Endopeptidases; Female; Humans; Intervertebral Disc Displacement; Risk; Skin Tests	1985
Skin testing for chymopapain allergy in chemonucleolysis. Surgical neurology, 1986, Volume: 25, Issue:3 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Female; Humans; Intervertebral Disc Displacement; Male; Preoperative Care; Skin Tests	1986
Skin tests for chymopapain allergy. Annals of allergy, 1985, Volume: 55, Issue:4 Topics: Anaphylaxis; Chymopapain; Drug Hypersensitivity; Humans; Intervertebral Disc Displacement; Premedication; Skin Tests	1985