1,2-dibromo-2,4-dicyanobutane and Dermatitis, Allergic Contact

1,2-dibromo-2,4-dicyanobutane has been researched along with Dermatitis, Allergic Contact in 86 studies

*Dermatitis, Allergic Contact: A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. [MeSH]

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (18.60)	18.2507
2000's	47 (54.65)	29.6817
2010's	20 (23.26)	24.3611
2020's	3 (3.49)	2.80

Authors

Authors	Studies
Geier, J; Kreft, B	1
García Castro, R; González de Arriba, M; Velasco Tirado, V	1
Borrego, L; Cordoba-Guijarro, S; Descalzo, MÁ; García-Doval, I; Gatica-Ortega, ME; Gimenez-Arnau, AM; Gonzalez-Perez, R; Heras-Mendaza, F; Hervella-Garces, M; Mercader-García, P; Miquel, J; Mora-Fernández, V; Ortiz-Frutos, FJ; Pastor-Nieto, MA; Perez-Feal, P; Rodriguez-Serna, M; Ruiz-Gonzalez, I; Sánchez-Pérez, J; Sanz-Sanchez, T; Serra-Baldrich, E; Silvestre-Salvador, JF; Zaragoza-Ninet, V	1
Adler, W; Gefeller, O; Uter, W	1
Deza, G; Giménez-Arnau, AM	1
Bandier, J; Johansen, JD; Kamstrup, MR; Thyssen, JP	1
Geier, J; Schnuch, A; Schubert, S	1
Li, LF; Zhao, J	1
Johansen, JD; Menné, T; Schwensen, JF; Thyssen, JP; White, IR	1
Bauer, A; Geier, J; Molin, S; Schubert, S; Skudlik, C	1
Bauer, A; Deza, G; Giménez-Arnau, AM; Johnston, GA; Mahler, V; Sanchez-Perez, J; Schuttelaar, ML; Silvestre, JF; Uter, W; Wilkinson, M	1
Blažienė, A; Linauskienė, K; Malinauskienė, L	1
Agner, T; Andersen, KE; Avnstorp, C; Johansen, JD; Kaaber, K; Kristensen, B; Kristensen, O; Laurberg, G; Menné, T; Nielsen, NH; Paulsen, E; Sommerlund, M; Thormann, J; Veien, N; Vissing, S	1
Basketter, DA; Irwin, A; Jowsey, IR	1
Andersen, KE; Mortz, CG	1
Fischer, LA; Johansen, JD; Menné, T	1
Carlsen, BC; Fischer, LA; Johansen, JD; Menné, T; Sosted, H; Vølund, A	1
Bordel-Gómez, MT; Miranda-Romero, A	1
Bhutani, T; Jacob, SE; Lampel, HP; Maier, LE	1
Andersen, KE; Fischer, LA; Johansen, JD; Menné, T; Voelund, A	1
Basketter, DA	1
Carlsen, BC; Engkilde, K; Johansen, JD; Lundov, MD; Menné, T; Thyssen, JP	1
Ada, S; Seçkin, D	1
Bauer, A; Eben, R; Frambach, Y; Heratizadeh, A; Killig, C; Mahler, V; Schnuch, A; Schuster, C; Simon, D; Soost, S; Szliska, C; Uter, W; Werfel, T; Worm, M	1
Andersen, KE; Johansen, JD; Karlberg, AT; Madsen, JT; Simonsson, C; Vogel, S	1
Dinnyés, M; Husz, S; Jurcsik, A; Kohánka, V; Nebenführer, L; Németh, I; Némethy, P; Pónyai, G; Temesvári, E	1
Fischer, LA; Johansen, JD; Menné, T; Voelund, A	1
Aakhus, AE; Warshaw, EM	1
Geier, J; Lessmann, H; Schnuch, A; Uter, W	1
Amaro, C; Cravo, M; Fernandes, C; Gonçalo, M; Santos, R	1
Andersen, KE; Brandão, FM; Bruynzeel, DP; Bruze, M; Diepgen, TL; Frosch, PJ; Giménez-Arnau, A; Gonçalo, M; Goossens, A; Johansen, JD; Lahti, A; Menné, T; Mowitz, M; Rustemeyer, T; Seidenari, S; Svedman, C; Tosti, A; Wahlberg, JE; White, IR; Wilkinson, JD	1
Devantier, C; Johansen, JD; Menné, T; Rastogi, S; Zachariae, C	1
Banerjee, P; McFadden, JP; Ross, JS; Rycroft, RJ; White, IR	1
Andersen, KE; Jensen, CD; Johansen, JD; Menné, T	2
Agner, T; Haslund, P; Held, E; Johansen, JD; Pedersen, LK; Vølund, A	1
Beck, MH; Young, HS	1
Agner, T; Held, E; Johansen, JD; Kynemund Pedersen, L	1
Johansen, JD; Menné, T; Rastogi, SC; Zachariae, C	1
Andersen, KE; Brandão, FM; Bruynzeel, DP; Bruze, M; Frosch, PJ; Goossens, A; Gruvberger, B; Lahti, A; Lindberg, M; Menné, T; Orton, D; Seidenari, S	1
Andersen, KE; Brandão, FM; Bruynzeel, DP; Bruze, M; Frosch, PJ; Goossens, A; Gruvberger, B; Lahti, A; Maibach, HI; Menné, T; Orton, D; Seidenari, S	1
Bruze, M; Goossens, A; Gruvberger, B	1
Andersen, KE; J Ohansen, JD; Jensen, CD; Menné, T	1
Avnstorp, C; Johansen, JD; Kaaber, K; Laurberg, G; Lauritzen, M; Thormann, J; Veien, NK	1
Aberer, W; Bauer, A; Bircher, A; Frosch, PJ; Hillen, U; Jappe, U; Katzer, K; Kelterer, D; Koch, P; Krautheim, A; Löffler, H; Mahler, V; Rakoski, J; Schnuch, A; Schuster, Ch; Uter, W; Worm, M	1
Akyol, A; Boyvat, A; Gürgey, E	1
Bruze, M; Goossens, A; Gruvberger, B; Hindsén, M; Pontén, A	1
Del Rio, MJ; García-Diez, A; Jiménez, YD; Sánchez-Pérez, J	1
Bruze, M; Gruvberger, B; Zimerson, E	1
Borrego, L; Hernández-Machín, B; Luján-Rodríguez, D; Peñate-Santana, Y	1
Jong, CT; Statham, BN	1
Oppel, T; Schnuch, A	1
Bergman, R; Weltfriend, S; Zoller, L	1
Andersen, KE; Basketter, DA; Evans, P; Jowsey, I; McFadden, J	1
Frowen, KE; Nixon, RL; Williams, JD	1
Johansen, JD; Menné, T; Thyssen, JP	1
Dhaoui, MA; Doss, N; Sfia, M	1
Brasch, J; Geier, J; Lessmann, H; Schnuch, A; Uter, W	1
Conde-Salazar, L; Heras, F; Marcano, ME	1
Bruze, M; Gruvberger, B; Isaksson, M	1
Rundervoort, GJ; Van Ginkel, CJ	1
Corazza, M; Mantovani, L; Roveggio, C; Virgili, A	1
Gebhart, M; Knopf, B; Stuhlert, A	1
Foulds, IS; O'Donnell, BF	1
Guerra, L; Tosti, A; Trevisi, P; Vincenzi, C	1
Blecher, P; Korting, HC	1
Coenraads, PJ; de Cock, PA; de Groot, AC; Jagtman, BA; Joost van der Kley, AM; Meinardi, MM; Smeenk, G; van der Valk, PG; van der Walle, HB; van Ginkel, CJ; van Joost, T; Weyland, JW	1
Geursen-Reitsma, AM; Okkerse, A; van Joost, T	1
Adessi, B; Brechat, N; Girardin, P; Laurent, R; Meyer, JP; Vigan, M; Vuitton, D	1
De Groot, AC; van Ginkel, CJ; Weyland, JW	1
Aalto-Korte, K; Alanko, K; Estlander, T; Jolanki, R; Kanerva, L	1
Aliaga, A; Gauchía, R; Miquel, JF; Rodríguez-Serna, M; Silvestre, JF	1
Primka, EJ; Taylor, JS	1
Fowler, JF; Jackson, JM	1
Armstrong, DK; Rycroft, RJ; Smith, HR	1
Boman, A; Montelius, J; Wahlberg, JE; Wahlkvist, H	1
Jones, AB; McFadden, JP; Ross, JS; Rycroft, RJ; Smith, HR; White, IR	1
Smith, KA; Tosti, A; Vincenzi, C	1
Condé-Salazar, L; Gonzalez, MA; Guimaraens, D; Hernández, MI	1
Brasch, J; Gefeller, O; Geier, J; Schnuch, A	1
Erdmann, SM; Merk, HF; Sachs, B	1
Franckson, T; Goos, M; Hillen, U	1
Fransway, AF	1
Beck, MH; Wong, CS	1
Andersen, KE; Brandao, FM; Bruynzeel, DP; Bruze, M; Camarasa, JM; Diepgen, TL; Ducombs, G; Frosch, PJ; Goossens, A; Lachappelle, JM; Lahti, A; Menné, T; Seidenari, S; Shaw, S; Tosti, A; Wahlberg, JE; Wilkinson, JD	1
Bauer, HI; Elsner, P; Kaatz, M; Kelterer, D; Thiele, J	1

Reviews

9 review(s) available for 1,2-dibromo-2,4-dicyanobutane and Dermatitis, Allergic Contact

Article	Year
[Preservative allergy : An enduring issue]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2020, Volume: 71, Issue:3 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Europe; Humans; Nitriles; Patch Tests; Predictive Value of Tests; Preservatives, Pharmaceutical; Retrospective Studies; Thiazoles	2020
Allergic contact dermatitis in preservatives: current standing and future options. Current opinion in allergy and clinical immunology, 2017, Volume: 17, Issue:4 Topics: Carbamates; Cosmetics; Dermatitis, Allergic Contact; Drug Hypersensitivity; Europe; Formaldehyde; Humans; Nitriles; Preservatives, Pharmaceutical; United States	2017
New aspects in allergic contact dermatitis. Current opinion in allergy and clinical immunology, 2008, Volume: 8, Issue:5 Topics: Allergens; Asteraceae; Cosmetics; Dermatitis, Allergic Contact; Hair Dyes; Humans; Nickel; Nitriles; Patch Tests	2008
Hand dermatitis: a focus on allergic contact dermatitis to biocides. Dermatologic clinics, 2009, Volume: 27, Issue:3 Topics: Allergens; Carbamates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Dermatology; Disinfectants; Formaldehyde; Glutaral; Hand Dermatoses; Humans; Methenamine; Nitriles; Parabens; Patch Tests; Preservatives, Pharmaceutical; Urea; Xylenes	2009
Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment. Cutaneous and ocular toxicology, 2010, Volume: 29, Issue:1 Topics: Allergens; Animals; Consumer Product Safety; Cosmetics; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Humans; Local Lymph Node Assay; Nitriles; Preservatives, Pharmaceutical; Reproducibility of Results; Risk Assessment; Skin; Skin Tests	2010
Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl k 400): regulatory issues, epidemiology, clinical characteristics, and management. Dermatitis : contact, atopic, occupational, drug, 2011, Volume: 22, Issue:3 Topics: Animals; Consumer Product Safety; Dermatitis, Allergic Contact; Ethylene Glycols; Europe; Guinea Pigs; Humans; Nitriles; Patch Tests; Preservatives, Pharmaceutical; United States	2011
[Current contact allergens]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2011, Volume: 62, Issue:10 Topics: Adolescent; Aldehydes; Allergens; Child; Chromates; Cross-Sectional Studies; Cyclohexenes; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Immunoglobulin E; Nickel; Nitriles; Patch Tests; Perfume; Population Surveillance; Preservatives, Pharmaceutical; Skin; Thiazoles	2011
Contact allergy epidemics and their controls. Contact dermatitis, 2007, Volume: 56, Issue:4 Topics: Chromium; Dermatitis, Allergic Contact; Formaldehyde; Humans; Nickel; Nitriles; Phenylenediamines; Risk Assessment; Thiazoles	2007
Frequency of sensitization to Euxyl K 400 in 889 cases. Contact dermatitis, 1993, Volume: 28, Issue:5 Topics: Cosmetics; Dermatitis, Allergic Contact; Ethylene Glycols; Humans; Incidence; Nitriles; Preservatives, Pharmaceutical	1993

Trials

7 trial(s) available for 1,2-dibromo-2,4-dicyanobutane and Dermatitis, Allergic Contact

Article	Year
Methyldibromoglutaronitrile allergy: relationship between patch test and repeated open application test thresholds. The British journal of dermatology, 2008, Volume: 159, Issue:5 Topics: Adult; Allergens; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Allowable Concentration; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical	2008
Methyldibromoglutaronitrile in rinse-off products causes allergic contact dermatitis: an experimental study. The British journal of dermatology, 2004, Volume: 150, Issue:1 Topics: Adult; Aged; Allergens; Cosmetics; Dermatitis, Allergic Contact; Double-Blind Method; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Soaps	2004
Patch testing with methyldibromo glutaronitrile, a multicentre study within the EECDRG. Contact dermatitis, 2005, Volume: 52, Issue:1 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Europe; Female; Humans; Male; Nitriles; Patch Tests; Predictive Value of Tests; Preservatives, Pharmaceutical; Research Design	2005
Repeated open application test with methyldibromo glutaronitrile, a multicentre study within the EECDRG. Contact dermatitis, 2005, Volume: 52, Issue:1 Topics: Adult; Aged; Allergens; Cosmetics; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Allowable Concentration; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Research Design; Time Factors	2005
Methyldibromo glutaronitrile contact allergy: effect of single versus repeated daily exposure. Contact dermatitis, 2005, Volume: 52, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Dermatitis, Allergic Contact; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Treatment Outcome	2005
Repeated open application tests with methyldibromoglutaronitrile in dermatitis patients with and without hypersensitivity to methyldibromoglutaronitrile. Dermatitis : contact, atopic, occupational, drug, 2007, Volume: 18, Issue:4 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Nitriles; Patch Tests; Research Design	2007
Tolerance to different toilet paper preparations: toxicological and allergological aspects. Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:4 Topics: Adult; Allergens; Anus Diseases; Cellulose; Dermatitis, Allergic Contact; Dermatitis, Irritant; Eczema; Female; Friction; Humans; Male; Nitriles; Paper; Patch Tests; Preservatives, Pharmaceutical; Prospective Studies; Reproducibility of Results; Skin Care; Thiazoles; Toxicology	1995

Other Studies

70 other study(ies) available for 1,2-dibromo-2,4-dicyanobutane and Dermatitis, Allergic Contact

Article	Year
Should methyldibromo glutaronitrile in the baseline series be tested? Results of the skin allergy unit of a fourth-level hospital in Spain. Contact dermatitis, 2021, Volume: 84, Issue:6 Topics: Case-Control Studies; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Male; Nitriles; Patch Tests; Retrospective Studies; Spain	2021
Should methyldibromo glutaronitrile continue to be used in the European baseline Series? A REIDAC national cross-sectional study. Contact dermatitis, 2021, Volume: 85, Issue:5 Topics: Adult; Allergens; Cosmetics; Cross-Sectional Studies; Dermatitis, Allergic Contact; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical	2021
Positive reactions to pairs of allergens associated with polysensitization: analysis of IVDK data with machine-learning techniques. Contact dermatitis, 2017, Volume: 76, Issue:4 Topics: Adult; Aged; Aldehydes; Allergens; Benzothiazoles; Biostatistics; Cyclohexenes; Dermatitis, Allergic Contact; Ethylene Glycols; Facial Dermatoses; Female; Foot Dermatoses; Hand Dermatoses; Head; Humans; Leg Dermatoses; Machine Learning; Male; Middle Aged; Nitriles; Patch Tests; Perfume; Sulfhydryl Compounds; Torso	2017
Contact allergy to methyldibromo glutaronitrile is still of clinical relevance. Contact dermatitis, 2017, Volume: 77, Issue:4 Topics: Adult; Dermatitis, Allergic Contact; Detergents; Female; Humans; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Sunscreening Agents	2017
Clinicians vs. epidemiologists: patch testing with methyldibromo glutaronitrile as a controversial issue. Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:6 Topics: Dermatitis, Allergic Contact; Dermatologists; Epidemiologists; False Positive Reactions; Female; Humans; Male; Nitriles; Patch Tests; Preservatives, Pharmaceutical	2019
Contact sensitization to cosmetic series of allergens in a general population in Beijing. Journal of cosmetic dermatology, 2014, Volume: 13, Issue:1 Topics: Adult; Allergens; Betaine; China; Cosmetics; Dermatitis, Allergic Contact; Female; Gallic Acid; Humans; Male; Methenamine; Nitriles; Patch Tests; Prevalence; Resins, Plant; Sex Factors; Thimerosal; Young Adult	2014
Failures in risk assessment and risk management for cosmetic preservatives in Europe and the impact on public health. Contact dermatitis, 2015, Volume: 73, Issue:3 Topics: Cosmetics; Dermatitis, Allergic Contact; Epidemics; Europe; Female; Humans; Male; Nitriles; Preservatives, Pharmaceutical; Prevalence; Retrospective Studies; Risk Assessment; Risk Management; Thiazoles	2015
Occupational contact sensitization in female geriatric nurses: Data of the Information Network of Departments of Dermatology (IVDK) 2005-2014. Journal of the European Academy of Dermatology and Venereology : JEADV, 2017, Volume: 31, Issue:3 Topics: Adult; Aged; Aldehydes; Allergens; Benzodiazepines; Benzothiazoles; Case-Control Studies; Cyclohexenes; Dermatitis, Allergic Contact; Disinfectants; Ditiocarb; Female; Geriatric Nursing; Gloves, Protective; Humans; Middle Aged; Nitriles; Occupational Diseases; Patch Tests; Perfume; Retrospective Studies; Thiazoles; Thiram; Young Adult	2017
Contact allergy to preservatives: ESSCA* results with the baseline series, 2009-2012. Journal of the European Academy of Dermatology and Venereology : JEADV, 2017, Volume: 31, Issue:4 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Carbamates; Dermatitis, Allergic Contact; Europe; Female; Formaldehyde; Humans; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Prevalence; Retrospective Studies; Thiazoles; Young Adult	2017
Time trends of contact allergy to the European baseline series in Lithuania. Contact dermatitis, 2017, Volume: 76, Issue:6 Topics: Age Factors; Allergens; Cobalt; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Formaldehyde; Hand Dermatoses; Humans; Leg Dermatoses; Lithuania; Male; Myroxylon; Nickel; Nitriles; Patch Tests; Perfume; Phenylenediamines; Population Surveillance; Potassium Dichromate; Prevalence; Resins, Plant; Retrospective Studies; Sex Factors; Thiazoles	2017
Decreasing trends in methyldibromo glutaronitrile contact allergy--following regulatory intervention. Contact dermatitis, 2008, Volume: 59, Issue:1 Topics: Adult; Consumer Product Safety; Cosmetics; Denmark; Dermatitis, Allergic Contact; Environmental Exposure; European Union; Female; Government Regulation; Humans; Male; Middle Aged; Nitriles; Patch Tests; Population Surveillance; Predictive Value of Tests; Preservatives, Pharmaceutical; Prevalence	2008
Proliferative responses in the local lymph node assay associated with concomitant exposure to 1,4-phenylenediamine and methyldibromo glutaronitrile: evidence for synergy? Contact dermatitis, 2008, Volume: 59, Issue:2 Topics: Allergens; Animals; Cell Proliferation; Dermatitis, Allergic Contact; Drug Interactions; Local Lymph Node Assay; Lymph Nodes; Mice; Nitriles; Phenylenediamines; Preservatives, Pharmaceutical; Risk Assessment; Skin	2008
Patch test dose-response study: polysensitized individuals do not express lower elicitation thresholds than single/double-sensitized individuals. The British journal of dermatology, 2009, Volume: 160, Issue:1 Topics: Dermatitis, Allergic Contact; Dose-Response Relationship, Immunologic; Female; Gene Expression; Humans; Irritants; Male; Middle Aged; Nickel; Nitriles; Patch Tests; Phenylenediamines; Sensitivity and Specificity; Skin	2009
[Contact sensitization to Euxyl K-400]. Actas dermo-sifiliograficas, 2009, Volume: 100, Issue:3 Topics: Adolescent; Adult; Aged; Dermatitis, Allergic Contact; Female; Humans; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Retrospective Studies; Young Adult	2009
The dose-response relationship between the patch test and ROAT and the potential use for regulatory purposes. Contact dermatitis, 2009, Volume: 61, Issue:4 Topics: Aldehydes; Cyclohexenes; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Eugenol; Humans; Mathematics; Nickel; Nitriles; Patch Tests; Perfume; Predictive Value of Tests; Preservatives, Pharmaceutical; Skin Tests	2009
Temporal trends of preservative allergy in Denmark (1985-2008). Contact dermatitis, 2010, Volume: 62, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbamates; Child; Child, Preschool; Consumer Product Safety; Cosmetics; Denmark; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Formaldehyde; Humans; Hydantoins; Male; Methenamine; Middle Aged; Nitriles; Parabens; Preservatives, Pharmaceutical; Retrospective Studies; Urea; Young Adult	2010
Patch testing in allergic contact dermatitis: is it useful to perform the cosmetic series in addition to the European standard series? Journal of the European Academy of Dermatology and Venereology : JEADV, 2010, Volume: 24, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Child; Cosmetics; Dermatitis, Allergic Contact; Europe; Female; Humans; Male; Middle Aged; Myristates; Nitriles; Patch Tests; Prospective Studies; Young Adult	2010
Quantitative repeated open application testing with a rinse-off product in methyldibromo glutaronitrile-sensitive patients: results of the IVDK. Contact dermatitis, 2010, Volume: 62, Issue:6 Topics: Adult; Aged; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Germany; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Skin; Soaps; Young Adult	2010
Ethosome formulation of contact allergens may enhance patch test reactions in patients. Contact dermatitis, 2010, Volume: 63, Issue:4 Topics: Allergens; Dermatitis, Allergic Contact; Drug Delivery Systems; Eugenol; Humans; Liposomes; Nitriles; Patch Tests; Preservatives, Pharmaceutical	2010
Contact hypersensitivity to epoxy resin, methyldibromoglutaronitrile, tixocortol pivalate and budesonide in Hungary: a study in 1448 patients. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2011, Volume: 146, Issue:1 Topics: Allergens; Budesonide; Dermatitis, Allergic Contact; Dermatitis, Contact; Dermatitis, Irritant; Epoxy Resins; Humans; Hungary; Hydrocortisone; Hypersensitivity, Immediate; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Urticaria	2011
Can exposure limitations for well-known contact allergens be simplified? An analysis of dose-response patch test data. Contact dermatitis, 2011, Volume: 64, Issue:6 Topics: Aldehydes; Allergens; Animals; Chromium; Cobalt; Cyclohexenes; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Environmental Exposure; Eugenol; Formaldehyde; Humans; Mice; Nickel; Nitriles; Patch Tests; Risk Assessment; Thiazoles	2011
Undisclosed methyldibromo glutaronitrile causing allergic contact dermatitis in a NSAID cream. Contact dermatitis, 2012, Volume: 67, Issue:3 Topics: Aged; Dermatitis, Allergic Contact; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Skin Cream	2012
Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008. Contact dermatitis, 2012, Volume: 67, Issue:5 Topics: Dermatitis, Allergic Contact; Disinfectants; Europe; Female; Follow-Up Studies; Formaldehyde; Humans; Male; Methenamine; Nitriles; Parabens; Patch Tests; Preservatives, Pharmaceutical; Thiazoles; Urea	2012
Methyldibromo glutaronitrile: clinical experience and exposure-based risk assessment. Contact dermatitis, 2003, Volume: 48, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Allergens; Denmark; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Risk Assessment	2003
Increased positive patch test reactivity to methyldibromo glutaronitrile. Contact dermatitis, 2003, Volume: 49, Issue:2 Topics: Adult; Dermatitis, Allergic Contact; Female; Humans; Male; Nitriles; Patch Tests; United Kingdom	2003
Influence of a detergent on skin response to methyldibromo glutaronitrile in sensitized individuals. Contact dermatitis, 2004, Volume: 50, Issue:1 Topics: Allergens; Colorimetry; Dermatitis, Allergic Contact; Detergents; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; Male; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Sodium Dodecyl Sulfate; Time Factors	2004
Post-coital contact dermatitis from methyldibromo glutaronitrile. Contact dermatitis, 2004, Volume: 50, Issue:1 Topics: Coitus; Dermatitis, Allergic Contact; Genital Diseases, Male; Humans; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Soaps	2004
Methyldibromoglutaronitrile in leave-on products elicits contact allergy at low concentration. The British journal of dermatology, 2004, Volume: 151, Issue:4 Topics: Adult; Aged; Cosmetics; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Emollients; Female; Humans; Lipids; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Risk Assessment	2004
Allergic contact dermatitis from methyldibromo glutaronitrile--clinical cases from 2003. Contact dermatitis, 2005, Volume: 52, Issue:1 Topics: Allergens; Cosmetics; Denmark; Dermatitis, Allergic Contact; Eczema; Female; Humans; Male; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies; Risk Factors	2005
Recommendation to include methyldibromo glutaronitrile in the European standard patch test series. Contact dermatitis, 2005, Volume: 52, Issue:1 Topics: Allergens; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Europe; Health Planning Guidelines; Humans; Maximum Allowable Concentration; Nitriles; Patch Tests; Practice Guidelines as Topic; Preservatives, Pharmaceutical; Research Design; Time Factors	2005
Contact allergy to methyldibromo glutaronitrile--data from a 'front line' network. Contact dermatitis, 2005, Volume: 52, Issue:3 Topics: Adult; Allergens; Cosmetics; Denmark; Dermatitis, Allergic Contact; Eczema; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Regression Analysis; Risk Factors	2005
Quantitative patch and repeated open application testing in methyldibromo glutaronitrile-sensitive patients. Contact dermatitis, 2005, Volume: 52, Issue:4 Topics: Adult; Aged; Allergens; Cosmetics; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Allowable Concentration; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Sensitivity and Specificity	2005
Contact sensitivity to preservatives in Turkey. Contact dermatitis, 2005, Volume: 52, Issue:6 Topics: Adolescent; Adult; Aged; Allergens; Benzalkonium Compounds; Child; Dermatitis, Allergic Contact; Female; Formaldehyde; Humans; Male; Medical Records; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies; Thimerosal; Turkey	2005
Allergic contact dermatitis from methyldibromoglutaronitrile. Dermatitis : contact, atopic, occupational, drug, 2005, Volume: 16, Issue:2 Topics: Adult; Allergens; Chromatography, High Pressure Liquid; Dermatitis, Allergic Contact; Diagnosis, Differential; False Negative Reactions; Female; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Patch Tests; Petrolatum; Predictive Value of Tests	2005
Allergic contact dermatitis due to methyldibromo glutaronitrile in make-up removal wipes. Contact dermatitis, 2005, Volume: 53, Issue:6 Topics: Adult; Cosmetics; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Humans; Nitriles; Preservatives, Pharmaceutical	2005
A clinically relevant contact allergy to methyldibromo glutaronitrile at 1% (0.32 mg/cm) detected by a patch test. Contact dermatitis, 2006, Volume: 54, Issue:1 Topics: Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Patch Tests	2006
Connubial allergic contact dermatitis to Euxyl K 400. Contact dermatitis, 2006, Volume: 54, Issue:2 Topics: Adult; Allergens; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Humans; Male; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Sexual Behavior; Thigh	2006
Increased retest reactivity by both patch and use test with methyldibromoglutaronitrile in sensitized individuals. Acta dermato-venereologica, 2006, Volume: 86, Issue:1 Topics: Adult; Aged; Allergens; Case-Control Studies; Dermatitis, Allergic Contact; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Soaps	2006
Methyldibromoglutaronitrile contact allergy--the beginning of the end? Contact dermatitis, 2006, Volume: 54, Issue:4 Topics: Dermatitis, Allergic Contact; Humans; Legislation, Drug; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical	2006
[The most frequent allergens in allergic contact dermatitis]. Deutsche medizinische Wochenschrift (1946), 2006, Jul-14, Volume: 131, Issue:28-29 Topics: Adult; Allergens; Ammonia; Balsams; Chromium; Cobalt; Coloring Agents; Dermatitis, Allergic Contact; Ethylene Glycols; Female; Humans; Lanolin; Male; Mercuric Chloride; Nickel; Nitriles; Patch Tests; Perfume; Phenylenediamines; Preservatives, Pharmaceutical; Resins, Plant; Retrospective Studies	2006
Preservatives sensitivity in Israel: a 10-year overview (1995-2004). Contact dermatitis, 2006, Volume: 55, Issue:4 Topics: Adult; Allergens; Dermatitis, Allergic Contact; Female; Formaldehyde; Humans; Israel; Male; Medical Records; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies; Thiazoles; Thimerosal	2006
Identification and classification of skin sensitizers: identifying false positives and false negatives. Contact dermatitis, 2006, Volume: 55, Issue:5 Topics: Allergens; Animals; Benzalkonium Compounds; Betaine; Cyclohexenes; Dermatitis, Allergic Contact; False Negative Reactions; False Positive Reactions; Humans; Limonene; Nitriles; Parabens; Preservatives, Pharmaceutical; Sodium Dodecyl Sulfate; Solvents; Sulfanilic Acids; Surface-Active Agents; Terpenes	2006
Allergic contact dermatitis from methyldibromo glutaronitrile in a sanitary pad and review of Australian clinic data. Contact dermatitis, 2007, Volume: 56, Issue:3 Topics: Allergens; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Feminine Hygiene Products; Humans; Male; Middle Aged; Nitriles; Occupations; Patch Tests; Preservatives, Pharmaceutical; Victoria; Vulva	2007
Consort allergic dermatitis to cosmetic agents in a 10-year-old young girl. Contact dermatitis, 2007, Volume: 57, Issue:1 Topics: Benzothiazoles; Child; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Mothers; Nitriles; Oils, Volatile; Patch Tests	2007
A further characteristic of susceptibility to contact allergy: sensitization to a weak contact allergen is associated with polysensitization. Results of the IVDK. Contact dermatitis, 2007, Volume: 56, Issue:6 Topics: Adult; Dermatitis, Allergic Contact; Disease Susceptibility; Female; Germany; Humans; Hypersensitivity, Immediate; Longitudinal Studies; Male; Middle Aged; Nitriles; Parabens; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index	2007
Occupational allergic contact dermatitis to methyldibromoglutaronitrile in hand degreasing toilet paper. Contact dermatitis, 2007, Volume: 57, Issue:2 Topics: Allergens; Automobiles; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Patch Tests	2007
Increasing incidence of contact allergy to the new preservative 1,2-dibromo-2,4-dicyanobutane (methyldibromoglutaronitrile). The British journal of dermatology, 1995, Volume: 132, Issue:6 Topics: Adult; Aged; Anus Diseases; Dermatitis, Allergic Contact; Ethylene Glycols; Facial Dermatoses; Female; Humans; Male; Middle Aged; Netherlands; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Prevalence	1995
Allergic contact dermatitis due to Euxyl K 400 in an ultrasonic gel. Contact dermatitis, 1993, Volume: 29, Issue:5 Topics: Aged; Dermatitis, Allergic Contact; Drug Eruptions; Ethylene Glycols; Gels; Humans; Male; Nitriles; Preservatives, Pharmaceutical; Ultrasonography; Urticaria	1993
Contact dermatitis due to dibromodicyanobutane in cucumber eye gel. Contact dermatitis, 1993, Volume: 29, Issue:2 Topics: Adult; Cosmetics; Dermatitis, Allergic Contact; Ethylene Glycols; Facial Dermatoses; Female; Humans; Nitriles	1993
Euxyl K 400: incidence of sensitization, patch test concentration and vehicle. Contact dermatitis, 1995, Volume: 33, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Italy; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Sensitivity and Specificity	1995
Methyldibromoglutaronitrile is an important contact allergen in The Netherlands. Contact dermatitis, 1996, Volume: 34, Issue:2 Topics: Adolescent; Adult; Aged; Allergens; Child; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Evaluation Studies as Topic; False Negative Reactions; Female; Humans; Male; Middle Aged; Netherlands; Nitriles; Patch Tests; Preservatives, Pharmaceutical	1996
Contact allergy to methyldibromoglutaronitrile and certain other preservatives. Contact dermatitis, 1996, Volume: 34, Issue:2 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Humans; Nitriles; Paint; Patch Tests; Solvents	1996
[A new allergen dibromodicyanobutane. Report of a study in 310 patients January-December 1994]. Annales de dermatologie et de venereologie, 1996, Volume: 123, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Child; Dermatitis, Allergic Contact; Eczema; Female; Humans; Male; Middle Aged; Nitriles; Occupational Diseases; Preservatives, Pharmaceutical; Skin Tests	1996
How to detect sensitization to Euxyl K 400. Contact dermatitis, 1996, Volume: 34, Issue:5 Topics: Allergens; Dermatitis, Allergic Contact; Humans; Nitriles; Patch Tests; Preservatives, Pharmaceutical	1996
Occupational allergic contact dermatitis caused by Euxyl K 400. Contact dermatitis, 1996, Volume: 35, Issue:3 Topics: Adult; Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Detergents; Female; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Printing	1996
Allergic contact dermatitis from Euxyl K 400 in a sunscreen cream. Contact dermatitis, 1996, Volume: 35, Issue:5 Topics: Cosmetics; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Humans; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Sunscreening Agents	1996
Three cases of contact allergy after chemical burns from methylchloroisothiazolinone/methylisothiazolinone: one with concomitant allergy to methyldibromoglutaronitrile/phenoxyethanol. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 1997, Volume: 8, Issue:1 Topics: Adult; Burns, Chemical; Dermatitis, Allergic Contact; Dermatitis, Occupational; Disinfectants; Humans; Industry; Male; Middle Aged; Nitriles; Patch Tests; Thiazoles	1997
Methyldibromoglutaronitrile (Euxyl K400): a new and important sensitizer in the United States? Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:6 Pt 1 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Drug Eruptions; Humans; Irritants; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies	1998
Contact allergy to methyldibromo glutaronitrile presenting as severe scalp seborrhoeic eczema. Contact dermatitis, 1999, Volume: 40, Issue:6 Topics: Adolescent; Dermatitis, Allergic Contact; Dermatitis, Seborrheic; Female; Hair Preparations; Humans; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Scalp Dermatoses	1999
Sensitizing potential in mice, guinea pig and man of the preservative Euxyl K 400 and its ingredient methyldibromo glutaronitrile. Contact dermatitis, 1999, Volume: 41, Issue:6 Topics: Allergens; Animals; Dermatitis, Allergic Contact; Dermatitis, Occupational; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Lymph Nodes; Mice; Mice, Inbred CBA; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Random Allocation	1999
Increased rate of patch test reactivity to methyldibromo glutaronitrile. Contact dermatitis, 2000, Volume: 42, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Child; Child, Preschool; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Infant; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Retrospective Studies; United Kingdom	2000
Provocative use testing of methyldibromo glutaronitrile in a cosmetic shampoo. Contact dermatitis, 2000, Volume: 42, Issue:2 Topics: Adolescent; Adult; Aged; Allergens; Cosmetics; Dermatitis, Allergic Contact; Female; Follow-Up Studies; Hair Preparations; Humans; Immunization; Male; Middle Aged; Nitriles; Preservatives, Pharmaceutical; Safety; Skin Tests	2000
Contact allergy to Euxyl K 400 in consecutively patch-tested patients. Contact dermatitis, 2000, Volume: 43, Issue:1 Topics: Adolescent; Adult; Aged; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Spain	2000
Patch testing with methyldibromoglutaronitrile. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2000, Volume: 11, Issue:4 Topics: Cosmetics; Dermatitis, Allergic Contact; Ethylene Glycols; Germany; Humans; Nitriles; Patch Tests; Predictive Value of Tests; Preservatives, Pharmaceutical	2000
Allergic contact dermatitis due to methyldibromo glutaronitrile in Euxyl K 400 in an ultrasonic gel. Contact dermatitis, 2001, Volume: 44, Issue:1 Topics: Allergens; Contrast Media; Dermatitis, Allergic Contact; Drug Hypersensitivity; Gels; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Ultrasonography	2001
Allergic contact dermatitis due to deer-fat cream (Hirschtalgcreme). Contact dermatitis, 2001, Volume: 44, Issue:1 Topics: Adult; Allergens; Cosmetics; Dermatitis, Allergic Contact; Female; Humans; Nitriles; Ointments; Patch Tests; Preservatives, Pharmaceutical	2001
Improved screening for methyldibromoglutaronitrile allergy. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 2000, Volume: 11, Issue:4 Topics: Dermatitis, Allergic Contact; Humans; Nitriles; Patch Tests; Predictive Value of Tests; Preservatives, Pharmaceutical	2000
Occupational contact allergy to methyldibromo glutaronitrile in abrasive cleansers and work creams. Contact dermatitis, 2001, Volume: 44, Issue:5 Topics: Adult; Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Hand Dermatoses; Humans; Male; Middle Aged; Nitriles; Patch Tests; Preservatives, Pharmaceutical	2001
Monitoring levels of preservative sensitivity in Europe. A 10-year overview (1991-2000). Contact dermatitis, 2002, Volume: 46, Issue:4 Topics: Allergens; Dermatitis, Allergic Contact; Europe; Formaldehyde; Humans; Nitriles; Patch Tests; Preservatives, Pharmaceutical; Thiazoles	2002
Contact allergy to methyldibromo glutaronitrile in Euxyl K 400 in a cosmetic cream for protection against a permanent wave solution. Contact dermatitis, 2002, Volume: 46, Issue:4 Topics: Allergens; Cosmetics; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Humans; Middle Aged; Nitriles; Preservatives, Pharmaceutical	2002