1,2,4-triazole has been researched along with Edema in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Grishina, M; Naumovich, V; Pathak, P; Potemkin, V; Shukla, PK; Verma, A | 1 |
| Avci, A; Can, ÖD; Gökhan-Kelekçi, N; Kandemir, Ü; Taşci, H; Tozkoparan, B | 1 |
| Bansode, MU; Doshi, GM; Somani, RR | 1 |
| Abdelall, EKA; Abdellatif, KRA; Elshemy, HAH; Hassanein, EHM; Kahk, NM; Philoppes, JN | 1 |
| Abdel-Aziz, M; Abdelhamid, D; Dalby, KN; Hassan, HA; Kaoud, TS; Mohassab, AM | 1 |
| Alam, O; Amir, M; Kamboj, P; Tariq, S | 1 |
| Abdel-Aziz, M; Abuo-Rahma, Gel-D; Ali, TF; Beshr, EA | 2 |
| Abdel-Alim, AA; Abdel-Moty, SG; Hussein, MA; Mohammed, AF | 1 |
| Ahmed, EA; Mekheimer, RA; Sadek, KU; Sayed, AA | 1 |
| Aktay, G; Ertan, M; Tozkoparan, B | 1 |
| Kalluraya, B; Rao, JN; Shetty, P; Sujith, KV | 1 |
| Aktay, G; Aytaç, SP; Göktaş, O; Kaynak, FB; Tozkoparan, B; Unüvar, S | 1 |
| Alam, MM; Alam, MS; Haider, S; Hamid, H; Nazreen, S; Shaharyar, M | 1 |
| Garigipati, S; Kundu, B; Semwal, A; Sharma, M; Sriram, D; Vanamala, D; Yogeeswari, P | 1 |
| Brukstus, A; Gaidelis, P; Labanauskas, L; Udrenaite, E | 1 |
| Amir, M; Javed, SA; Khan, SA; Kumar, H | 1 |
17 other study(ies) available for 1,2,4-triazole and Edema
| Article | Year |
|---|---|
1,2,4-Triazole-conjugated 1,3,4-thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan-induced inflammation by lessening proinflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Inflammation; Inflammation Mediators; Molecular Docking Simulation; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Thiadiazoles; Triazoles | 2020 |
Synthesis, characterization, and in vivo pharmacological evaluation of novel mannich bases derived from 1,2,4-triazole containing a naproxen moiety.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Drug Design; Edema; Humans; Male; Mannich Bases; Mice, Inbred BALB C; Molecular Docking Simulation; Naproxen; Pain; Triazoles | 2020 |
Evaluation of Biological Activity of Derivatives of 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and 1,2,4-Triazole.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythrocyte Membrane; Female; Male; Oxadiazoles; Peptide Hydrolases; Protease Inhibitors; Rats; Thiadiazoles; Triazoles | 2021 |
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Edema; Inflammation; Male; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles | 2021 |
Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Enzyme Activation; Gastric Mucosa; Inhibitory Concentration 50; Kinetics; Liver; Molecular Docking Simulation; Nitric Oxide; Oximes; Quinolines; Rats; Structure-Activity Relationship; Triazoles | 2017 |
1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Edema; Molecular Docking Simulation; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Rats, Wistar; Triazoles | 2018 |
New nitric oxide donating 1,2,4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Edema; Humans; Kidney Neoplasms; Male; Nitric Oxide; Nitric Oxide Donors; Oximes; Rats; Stomach; Triazoles; Ulcer | 2013 |
Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Drug Design; Edema; Male; Mice; Molecular Docking Simulation; Pain; Protein Binding; Rats; Structure-Activity Relationship; Triazoles | 2013 |
1,2,4-Triazole/oxime hybrids as new strategy for nitric oxide donors: Synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Edema; Humans; Male; Neoplasms; Nitric Oxide Donors; Oximes; Rats; Stomach Ulcer; Triazoles | 2014 |
Synthesis and Characterization of New 1,2,4-Triazolo[1,5-a]pyridines That Extend the Life Span of Caenorhabiditis elegans via Their Anti-Inflammatory/Antioxidant Effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Caenorhabditis elegans; Carrageenan; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Glycation End Products, Advanced; Glycosylation; Heat-Shock Response; Longevity; Male; Molecular Structure; Oxidative Stress; Picrates; Pyridines; Rats; Structure-Activity Relationship; Time Factors; Triazoles | 2015 |
Investigation of antioxidant properties of some 6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzyl Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Ethanol; Gastrointestinal Diseases; Inhibitory Concentration 50; Lipid Peroxidation; Male; Mice; Stomach Ulcer; Time Factors; Triazoles | 2009 |
Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Edema; Escherichia coli; Ibuprofen; Inflammation; Mannich Bases; Mice; Pain; Rats; Rats, Wistar; Schiff Bases; Staphylococcus aureus; Triazoles | 2009 |
Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Female; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Pain Measurement; Thiadiazines; Triazoles; Ulcer | 2009 |
Synthesis of novel 8-hydroxy quinolin based 1,3,4-oxadiazoles and S-substituted 1,2,4-triazole derivatives and evaluation of their anti-inflammatory, analgesic, ulcerogenic and anti-microbial activities.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Quinolones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles | 2011 |
Discovery of novel 1,2,4-triazol-5-ones as tumor necrosis factor-alpha inhibitors for the treatment of neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Humans; Mice; Neuralgia; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha | 2012 |
Synthesis of 5-(2-,3- and 4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol derivatives exhibiting anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Sulfhydryl Compounds; Triazoles | 2004 |
1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carrageenan; Diphenylacetic Acids; Drug Evaluation, Preclinical; Edema; Female; Gastric Mucosa; Lipid Peroxidation; Liver; Male; Mice; Molecular Structure; Oxadiazoles; Rats; Rats, Wistar; Stereoisomerism; Stomach Ulcer; Thiadiazoles; Triazoles | 2008 |