Compounds > 1,2,3,4-tetrahydroisoquinoline
Page last updated: 2024-08-17

1,2,3,4-tetrahydroisoquinoline and Disease Models, Animal

1,2,3,4-tetrahydroisoquinoline has been researched along with Disease Models, Animal in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antkiewicz-Michaluk, L; Michaluk, J; Możdżeń, E; Romańska, I; Wąsik, A2
Härkönen, P; Hedblom, A; Johansson, ME; Larsson, R; Miftakhova, RR; Persson, JL; Sarwar, M; Semenas, J; Shcherbina, L; Sterner, O1
Altshuler, HL; Shippenberg, TS1
Airaksinen, MM; Altshuler, HL; Rusi, M; Sinclair, JD1
Melchior, CL1
Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T1
Abe, K; Ishiwata, K; Kawamura, K; Koyanagi, Y; Saitoh, T; Sano, T; Senda, M; Taguchi, K; Toda, J1
Hirobe, M; Makino, Y; Ohta, S; Tachikawa, O; Tasaki, Y1

Other Studies

9 other study(ies) available for 1,2,3,4-tetrahydroisoquinoline and Disease Models, Animal

ArticleYear
Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:3

    Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb Suspension; Imipramine; Male; Mice; Mice, Inbred C57BL; Swimming; Tetrahydroisoquinolines

2017
Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat.
    Neurotoxicity research, 2014, Volume: 26, Issue:1

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dopamine; Hypothalamus; Male; Motor Activity; Neuropsychological Tests; Norepinephrine; Nucleus Accumbens; Rats, Wistar; Reserpine; Serotonin; Tetrahydroisoquinolines

2014
The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-02, Volume: 111, Issue:35

    Topics: Animals; Apoptosis; Cell Proliferation; Cell Survival; Diketopiperazines; Disease Models, Animal; Drug Discovery; Humans; Indoles; Isoquinolines; Male; Mice; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays

2014
Tetrahydroisoquinoline and opioid substrates of alcohol actions.
    Progress in clinical and biological research, 1982, Volume: 90

    Topics: Alcoholism; Animals; Disease Models, Animal; Ethanol; Humans; Isoquinolines; Macaca mulatta; Male; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Self Administration; Tetrahydroisoquinolines

1982
Relating TIQ's, opiates, and ethanol.
    Progress in clinical and biological research, 1982, Volume: 90

    Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Ethanol; Humans; Isoquinolines; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines

1982
TIQs block the development of environment dependent tolerance to ethanol.
    Progress in clinical and biological research, 1982, Volume: 90

    Topics: Alcoholism; Animals; Brain; Disease Models, Animal; Drug Tolerance; Ethanol; Humans; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Sleep; Substance-Related Disorders; Tetrahydroisoquinolines

1982
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
    Brain research bulletin, 2001, Sep-01, Volume: 56, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypokinesia; Immunohistochemistry; Isoquinolines; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Serotonin; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase

2001
Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
    Journal of neurochemistry, 2001, Volume: 79, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hypokinesia; Isoquinolines; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Parkinsonian Disorders; Radioligand Assay; Receptors, Dopamine D2; Stereoisomerism; Substantia Nigra; Synapses; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase; Up-Regulation

2001
Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal model of a poor debrisoquine metabolizer.
    Life sciences, 1990, Volume: 46, Issue:8

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Debrisoquin; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Microsomes, Liver; Parkinson Disease; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines

1990