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1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose and Disease Models, Animal

1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose has been researched along with Disease Models, Animal in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's9 (56.25)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Dhital, S; Rice, CD; Vyavahare, NR1
Dhital, S; Vyavahare, NR1
Chen, CJ; Fang, CC; Hsiao, HH; Hsiao, HP; Kant, R; Lin, KJ; Lu, CK; Nguyen, HM; Yen, CH1
Laursen, MS; Lindholt, JS; Mahmoud, H; Schack, AS; Steffensen, LB; Stubbe, J1
Feng, Y; Gong, W; Liu, Y; Tu, C; Tu, Z; Zhang, Y1
Chen, SJ; Li, Q; Nie, J; Zhang, Q1
Han, MJ; Hyam, SR; Jang, SE; Jeong, JJ; Kim, DH1
Huang, Y; Kim, YH; Kumazoe, M; Lin, IC; Murata, M; Nakahara, K; Tachibana, H; Won, YS; Yamashita, S; Yang, X1
Choi, MS; Jeong, AJ; Joo, EY; Kim, BH; Kwon, S; Lee, H; Lee, HG; Lee, J; Lee, SH; Noh, KH; Park, JY; Ye, SK; Yi, EH1
Chowdhury, A; Karamched, S; Nosoudi, N; Parasaram, V; Siclari, S; Vyavahare, N1
Chun, K; Kim, SO; Lee, SH1
Chowdhury, A; Gerard, P; Karamched, S; Nosoudi, N; Parasaram, V; Parrish, J; Siclari, S; Vyavahare, N1
Arai, H; Fujiwara, H; Furukawa, K; Hara, M; Higuchi, M; Ikarashi, Y; Iwasaki, K; Kase, Y; Kudo, Y; Maeda, S; Saido, TC; Sekiguchi, K; Tabuchi, M; Takashima, A; Yaegashi, N; Yamaguchi, T1
Fukuoka, J; Kadowaki, M; Kageyama, S; Kageyama-Yahara, N; Katagiri, T; Maeda, F; Suehiro, Y; Yamamoto, T1
Isenburg, JC; Simionescu, DT; Starcher, BC; Vyavahare, NR1

Other Studies

16 other study(ies) available for 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Reversal of elastase-induced abdominal aortic aneurysm following the delivery of nanoparticle-based pentagalloyl glucose (PGG) is associated with reduced inflammatory and immune markers.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Hydrolyzable Tannins; Inflammation; Male; Mice; Nanoparticle Drug Delivery System; Pancreatic Elastase

2021
Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Animals; Antibodies; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Drug Carriers; Elastin; Extracellular Matrix; Gold; Humans; Hydrolyzable Tannins; Immunoconjugates; Injections, Intravenous; Male; Metal Nanoparticles; Mice; Pancreatic Elastase; Serum Albumin, Bovine; Ultrasonography

2020
1,2,3,4,6 penta-O-galloyl-β-D-glucose ameliorates high-fat diet-induced nonalcoholic fatty liver disease and maintains the expression of genes involved in lipid homeostasis in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Animals; Biomarkers; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Homeostasis; Hydrolyzable Tannins; Lipid Metabolism; Lipids; Liver; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2020
Intraluminal infusion of Penta-Galloyl Glucose reduces abdominal aortic aneurysm development in the elastase rat model.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Elastic Tissue; Hydrolyzable Tannins; Infusions, Intralesional; Male; Pancreatic Elastase; Protein-Lysine 6-Oxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger

2020
Inhibition of Rabies Virus by 1,2,3,4,6-Penta-
    Viruses, 2018, 04-17, Volume: 10, Issue:4

    Topics: Animals; Antiviral Agents; Autophagy; Disease Models, Animal; Female; Hydrolyzable Tannins; Mice; Rabies; Rabies virus; Survival Analysis; Sweetening Agents; TOR Serine-Threonine Kinases; Virus Replication

2018
Protective effects of ethyl gallate and pentagalloylglucose, the active components of Qingwen Baidu Decoction, against lipopolysaccharide-induced acute lung injury in rats.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Acute Lung Injury; Animals; Capillary Permeability; Disease Models, Animal; Drugs, Chinese Herbal; Gallic Acid; Hydrolyzable Tannins; Lipopolysaccharides; Lung; Male; Neutrophil Infiltration; Pulmonary Edema; Rats, Sprague-Dawley

2019
Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways.
    British journal of pharmacology, 2013, Volume: 170, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cells, Cultured; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Hydrolyzable Tannins; Inflammation Mediators; Interleukin-1 Receptor-Associated Kinases; Macrophages, Peritoneal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Differentiation Factor 88; NF-kappa B; Phosphorylation; RNA Interference; Toll-Like Receptor 4; Transfection; Trinitrobenzenesulfonic Acid

2013
1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice.
    International immunopharmacology, 2015, Volume: 26, Issue:1

    Topics: Animals; Anti-Allergic Agents; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Hydrolyzable Tannins; Hypersensitivity, Immediate; Immunoglobulin E; Lymphocyte Count; Male; Mice, Inbred BALB C; Ovalbumin; Spleen; T-Lymphocytes, Regulatory

2015
Photoprotective Potential of Penta-O-Galloyl-β-DGlucose by Targeting NF-κB and MAPK Signaling in UVB Radiation-Induced Human Dermal Fibroblasts and Mouse Skin.
    Molecules and cells, 2015, Volume: 38, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cells, Cultured; Disease Models, Animal; Fibroblasts; Humans; Hydrolyzable Tannins; Male; MAP Kinase Signaling System; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Phosphorylation; Radiodermatitis; Skin; Sunscreening Agents; Ultraviolet Rays

2015
Systemic Delivery of Nanoparticles Loaded with Pentagalloyl Glucose Protects Elastic Lamina and Prevents Abdominal Aortic Aneurysm in Rats.
    Journal of cardiovascular translational research, 2016, Volume: 9, Issue:5-6

    Topics: Animals; Antibodies; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cells, Cultured; Cytoprotection; Disease Models, Animal; Drug Compounding; Drug Liberation; Elastic Tissue; Elastin; Hydrolyzable Tannins; Injections, Intravenous; Macrophages; Male; Matrix Metalloproteinases; Nanoparticles; Particle Size; Proteolysis; Rats, Sprague-Dawley; Solubility; Vascular Calcification

2016
Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain.
    International journal of molecular medicine, 2016, Volume: 38, Issue:4

    Topics: Analgesics; Animals; Antioxidants; Brain; Cell Survival; Disease Models, Animal; Gene Expression Regulation; Hydrolyzable Tannins; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Movement; Nitric Oxide; Pain; RAW 264.7 Cells; RNA, Messenger

2016
Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles.
    Theranostics, 2016, Volume: 6, Issue:11

    Topics: Animals; Aortic Aneurysm; Arachnida; Calcium Chelating Agents; Disease Models, Animal; Drug Therapy, Combination; Edetic Acid; Histocytochemistry; Hydrolyzable Tannins; Nanoparticles; Polyphenols; Rats; Treatment Outcome; Vascular Calcification

2016
A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo.
    Journal of neurochemistry, 2009, Volume: 109, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Behavior, Animal; Cell Line, Transformed; Cell Survival; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydrolyzable Tannins; Memory; Mice; Mice, Transgenic; Models, Molecular; Paeonia; Peptide Fragments; Phytotherapy; Plant Extracts; Time Factors

2009
Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.
    FEBS letters, 2010, Jan-04, Volume: 584, Issue:1

    Topics: Animals; Cell Degranulation; Cell Membrane; Cells, Cultured; Diarrhea; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Food Hypersensitivity; Hydrolyzable Tannins; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred BALB C; Paeonia; Receptors, IgE

2010
Elastin stabilization for treatment of abdominal aortic aneurysms.
    Circulation, 2007, Apr-03, Volume: 115, Issue:13

    Topics: Administration, Topical; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcinosis; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Elastin; Fibroblasts; Hydrolyzable Tannins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Denaturation; Rats; Rats, Sprague-Dawley

2007