1,10-phenanthroline has been researched along with Melanoma in 6 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo studies revealed no toxic effects after parenteral administration of Cuphen liposomes." | 1.43 | Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells. ( Casini, A; Castro, RE; Gaspar, MM; Nave, M; Rodrigues, CM; Soveral, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ghosh, G | 1 |
| Yin, H | 1 |
| Monro, SMA | 1 |
| Sainuddin, T | 1 |
| Lapoot, L | 1 |
| Greer, A | 1 |
| McFarland, SA | 1 |
| Nave, M | 1 |
| Castro, RE | 1 |
| Rodrigues, CM | 1 |
| Casini, A | 1 |
| Soveral, G | 1 |
| Gaspar, MM | 1 |
| Gomez-Sarosi, LA | 1 |
| Strasberg-Rieber, M | 1 |
| Rieber, M | 1 |
| Löffek, S | 1 |
| Zigrino, P | 1 |
| Steiger, J | 1 |
| Kurschat, P | 1 |
| Smola, H | 1 |
| Mauch, C | 1 |
| Ahrens, T | 1 |
| Sleeman, JP | 1 |
| Schempp, CM | 1 |
| Howells, N | 1 |
| Hofmann, M | 1 |
| Ponta, H | 1 |
| Herrlich, P | 1 |
| Simon, JC | 1 |
| Keren, Z | 1 |
| Leland, F | 1 |
| Nakajima, M | 1 |
| LeGrue, SJ | 1 |
6 other studies available for 1,10-phenanthroline and Melanoma
| Article | Year |
|---|---|
Synthesis and Characterization of Ru(II) Complexes with π-Expansive Imidazophen Ligands for the Photokilling of Human Melanoma Cells.
Topics: Cell Line, Tumor; Coordination Complexes; Humans; Ligands; Melanoma; Phenanthrolines; Photochemother | 2020 |
Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells.
Topics: Animals; Antineoplastic Agents; Aquaporins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Col | 2016 |
H(2)O(2) preferentially synergizes with nitroprusside to induce apoptosis associated with superoxide dismutase dysregulation in human melanoma irrespective of p53 status: Antagonism by o-phenanthroline.
Topics: Apoptosis; Cell Proliferation; Drug Synergism; Genotype; Humans; Hydrogen Peroxide; Melanoma; Nitrop | 2010 |
Melanoma cell-derived vascular endothelial growth factor induces endothelial tubulogenesis within fibrin gels by a metalloproteinase-mediated mechanism.
Topics: Endothelium, Vascular; Fibrin; Gels; Humans; Melanoma; Metalloendopeptidases; Metalloproteases; Neov | 2006 |
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Adhesion; Cell Division; Culture Media; Glycopept | 2001 |
Inhibition of experimental metastasis and extracellular matrix degradation by butanol extracts from B16-F1 murine melanoma.
Topics: 1-Butanol; Animals; Butanols; Cell Line; Chondroitin Sulfate Proteoglycans; Extracellular Matrix; He | 1989 |