1,10-phenanthroline has been researched along with Leukemia, Myeloid, Acute in 3 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human acute myeloid leukemia cell line HL-60, MTT assay, and Trypan blue assay were used to test the antileukemic, the cell viability, and the structural integrity of the cell membrane and cell proliferation properties of (chloro)(Phen)( N-propyl-norfloxacinato)copper(II) (complex 1), respectively." | 1.35 | Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities. ( Efthimiadou, EK; Karaliota, A; Katsarou, ME; Psomas, G; Vourloumis, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Katsarou, ME | 1 |
| Efthimiadou, EK | 1 |
| Psomas, G | 1 |
| Karaliota, A | 1 |
| Vourloumis, D | 1 |
| Guillon, J | 1 |
| Denevault-Sabourin, C | 1 |
| Chevret, E | 1 |
| Brachet-Botineau, M | 1 |
| Milano, V | 1 |
| Guédin-Beaurepaire, A | 1 |
| Moreau, S | 1 |
| Ronga, L | 1 |
| Savrimoutou, S | 1 |
| Rubio, S | 1 |
| Ferrer, J | 1 |
| Lamarche, J | 1 |
| Mergny, JL | 1 |
| Viaud-Massuard, MC | 1 |
| Ranz, M | 1 |
| Largy, E | 1 |
| Gabelica, V | 1 |
| Rosu, F | 1 |
| Gouilleux, F | 1 |
| Desplat, V | 1 |
| Matsuzaki, A | 1 |
| Janowska-Wieczorek, A | 1 |
3 other studies available for 1,10-phenanthroline and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Copper; | 2008 |
Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Fluorescence Resonance Energy Transfer; G-Quad | 2021 |
Unstimulated human acute myelogenous leukemia blasts secrete matrix metalloproteinases.
Topics: Adult; Aged; Basement Membrane; Collagen; Collagenases; Cysteine Proteinase Inhibitors; Drug Combina | 1997 |