1,10-phenanthroline has been researched along with Leucocythaemia in 2 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrrolidine dithiocarbamate (PDTC) has been considered as a potential anticancer drug due to its powerful apoptogenic effect towards cancer cells, where Cu(2+) plays a distinct yet undefined role." | 5.35 | Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. ( Chen, J; Du, C; Kang, J; Wang, J, 2008) |
| "Pyrrolidine dithiocarbamate (PDTC) has been considered as a potential anticancer drug due to its powerful apoptogenic effect towards cancer cells, where Cu(2+) plays a distinct yet undefined role." | 1.35 | Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. ( Chen, J; Du, C; Kang, J; Wang, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 1 |
| Du, C | 1 |
| Kang, J | 1 |
| Wang, J | 1 |
| Rebeiz, N | 1 |
| Arkins, S | 1 |
| Kelley, KW | 1 |
| Durack, G | 1 |
| Rebeiz, CA | 1 |
2 other studies available for 1,10-phenanthroline and Leucocythaemia
| Article | Year |
|---|---|
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis.
Topics: Acetylation; Apoptosis; Butyrates; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Copper; C | 2008 |
Modulator of heme biosynthesis induces apoptosis in leukemia cells.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Cycle; Cell Division; Cell Membrane Permeability; Cell | 2001 |