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1,10-phenanthroline and Breast Neoplasms

1,10-phenanthroline has been researched along with Breast Neoplasms in 13 studies

1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"The cancer chemotherapeutic potential of surfactant-cobalt(III) complexes, cis-[Co(bpy)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (1) and cis-[Co(phen)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (2) (bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline) on MCF-7 breast cancer cell was determined adopting MTT assay and specific staining techniques."7.77Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line. ( Akbarsha, MA; Arunachalam, S; Dinesh, M; Krishnamurthy, H; Kumar, RS; Paul, CP; Riyasdeen, A; Srinag, S, 2011)
"Our results indicate that human breast cancer cells contain a neutral phosphoramidon-sensitive metalloproteinase which can process big ET-1 to ET-1."5.29Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts. ( Patel, KV; Schrey, MP, 1995)
"The breast cancer stem cell (CSC) and bulk breast cancer cell potency of a series of metallopeptides containing dichloro(1,10-phenanthroline)copper(II) and various organelle-targeting peptide sequences is reported."3.88A Copper(II) Phenanthroline Metallopeptide That Targets and Disrupts Mitochondrial Function in Breast Cancer Stem Cells. ( Bineva-Todd, G; Eskandari, A; Laws, K; Lu, C; O'Reilly, N; Suntharalingam, K, 2018)
"The cancer chemotherapeutic potential of surfactant-cobalt(III) complexes, cis-[Co(bpy)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (1) and cis-[Co(phen)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (2) (bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline) on MCF-7 breast cancer cell was determined adopting MTT assay and specific staining techniques."3.77Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line. ( Akbarsha, MA; Arunachalam, S; Dinesh, M; Krishnamurthy, H; Kumar, RS; Paul, CP; Riyasdeen, A; Srinag, S, 2011)
" We purified ADAM 12 from the urine of breast cancer patients via Q-Sepharose anion exchange and gelatin-Sepharose affinity chromatography followed by protein identification by matrix-assisted laser desorption/ionization-time of flight mass spectrometry."3.72ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage. ( Moses, MA; Pories, SE; Roy, R; Wewer, UM; Zurakowski, D, 2004)
"Cryosections of several breast cancer tissues were put on this gelatin film and incubated for 16 hrs at 37 degrees C."1.31Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography. ( Hara, Y; Iwase, H; Iwase, T; Iwata, H; Kobayashi, S; Miura, S; Mizutani, M; Nemori, R; Obata, Y; Omoto, Y; Toyama, T; Yamamoto, M; Yamashita, H, 2001)
"Treatment of human breast cancer cells with either H2O2 or hyperoxia increased the activity of spermidine/spermine N1-acetyltransferase (SSAT)."1.30Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species. ( Chopra, S; Wallace, HM, 1998)
"Our results indicate that human breast cancer cells contain a neutral phosphoramidon-sensitive metalloproteinase which can process big ET-1 to ET-1."1.29Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts. ( Patel, KV; Schrey, MP, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laws, K1
Bineva-Todd, G1
Eskandari, A1
Lu, C1
O'Reilly, N1
Suntharalingam, K1
Mohammadizadeh, F1
Falahati-Pour, SK1
Rezaei, A1
Mohamadi, M1
Hajizadeh, MR1
Mirzaei, MR1
Khoshdel, A1
Fahmidehkar, MA1
Mahmoodi, M1
Alves, LN1
Missailidis, S1
Lage, CAS1
DE Almeida, CEB1
Zhang, Z1
Wang, H2
Wang, Q1
Yan, M1
Bi, C1
Sun, S1
Fan, Y1
Kim, DH1
Kim, JH1
Kim, EH1
Na, HK1
Cha, YN1
Chung, JH1
Surh, YJ1
Bandarra, D1
Lopes, M1
Lopes, T1
Almeida, J1
Saraiva, MS1
Vasconcellos-Dias, M1
Nunes, CD1
Félix, V1
Brandão, P1
Vaz, PD1
Meireles, M1
Calhorda, MJ1
Chin, LF1
Kong, SM1
Seng, HL1
Khoo, KS1
Vikneswaran, R1
Teoh, SG1
Ahmad, M1
Khoo, SB1
Maah, MJ1
Ng, CH1
Kumar, RS1
Riyasdeen, A1
Dinesh, M1
Paul, CP1
Srinag, S1
Krishnamurthy, H1
Arunachalam, S1
Akbarsha, MA1
Roy, R1
Wewer, UM1
Zurakowski, D1
Pories, SE1
Moses, MA1
Patel, KV1
Schrey, MP1
Dinda, S1
Kodali-Gali, S1
Sevilla, L1
Burkley, M1
Hurd, C1
Moudgil, VK1
Chopra, S1
Wallace, HM1
Iwata, H1
Yamamoto, M1
Nemori, R1
Mizutani, M1
Iwase, T1
Miura, S1
Obata, Y1
Hara, Y1
Omoto, Y1
Toyama, T1
Yamashita, H1
Iwase, H1
Kobayashi, S1

Other Studies

13 other studies available for 1,10-phenanthroline and Breast Neoplasms

ArticleYear
A Copper(II) Phenanthroline Metallopeptide That Targets and Disrupts Mitochondrial Function in Breast Cancer Stem Cells.
    Angewandte Chemie (International ed. in English), 2018, 01-02, Volume: 57, Issue:1

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coordination Co

2018
The cytotoxicity effects of a novel Cu complex on MCF-7 human breast cancerous cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2018, Volume: 31, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Coordination Complexes; Copper; Fema

2018
Anti-MUC1 Aptamer as Carrier Tool of the Potential Radiosensitizer 1,10 Phenanthroline in MCF-7 Breast Cancer Cells.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Aptamers, Nucleotide; Breast Neoplasms; Drug Carriers; Endocytosis; Feasibility Studies; Female; Fer

2019
Anticancer activity and computational modeling of ternary copper (II) complexes with 3-indolecarboxylic acid and 1,10-phenanthroline.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Copper; Female; Humans; Indoles;

2016
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
    Carcinogenesis, 2009, Volume: 30, Issue:4

    Topics: Breast Neoplasms; Cell Movement; Heme Oxygenase-1; Humans; Immunologic Factors; Iron; Iron Chelating

2009
Mo(II) complexes: a new family of cytotoxic agents?
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:11

    Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dos

2010
Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
    Journal of inorganic biochemistry, 2011, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chelating Agents; Cobalt;

2011
Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:7

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tu

2011
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: ADAM Proteins; ADAM12 Protein; Adult; Aged; Amino Acid Sequence; Animals; Blotting, Western; Breast

2004
Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts.
    British journal of cancer, 1995, Volume: 71, Issue:3

    Topics: Aspartic Acid Endopeptidases; Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Cultur

1995
Inhibition of proliferation of T47D human breast cancer cells: alterations in progesterone receptor and p53 tumor suppressor protein.
    Molecular and cellular biochemistry, 1997, Volume: 175, Issue:1-2

    Topics: Antineoplastic Agents; Aurintricarboxylic Acid; Blotting, Western; Breast Neoplasms; Cell Division;

1997
Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species.
    Biochemical pharmacology, 1998, Apr-01, Volume: 55, Issue:7

    Topics: Acetyltransferases; Breast Neoplasms; Free Radical Scavengers; Free Radicals; Humans; Hyperoxia; Iro

1998
Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.
    Breast cancer (Tokyo, Japan), 2001, Volume: 8, Issue:2

    Topics: Azo Compounds; Breast Neoplasms; Cell Nucleus; Enzyme Inhibitors; Gelatin; Gelatinases; Hematoxylin;

2001