1,10-phenanthroline has been researched along with Breast Cancer in 13 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cancer chemotherapeutic potential of surfactant-cobalt(III) complexes, cis-[Co(bpy)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (1) and cis-[Co(phen)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (2) (bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline) on MCF-7 breast cancer cell was determined adopting MTT assay and specific staining techniques." | 7.77 | Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line. ( Akbarsha, MA; Arunachalam, S; Dinesh, M; Krishnamurthy, H; Kumar, RS; Paul, CP; Riyasdeen, A; Srinag, S, 2011) |
| "Our results indicate that human breast cancer cells contain a neutral phosphoramidon-sensitive metalloproteinase which can process big ET-1 to ET-1." | 5.29 | Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts. ( Patel, KV; Schrey, MP, 1995) |
| "The breast cancer stem cell (CSC) and bulk breast cancer cell potency of a series of metallopeptides containing dichloro(1,10-phenanthroline)copper(II) and various organelle-targeting peptide sequences is reported." | 3.88 | A Copper(II) Phenanthroline Metallopeptide That Targets and Disrupts Mitochondrial Function in Breast Cancer Stem Cells. ( Bineva-Todd, G; Eskandari, A; Laws, K; Lu, C; O'Reilly, N; Suntharalingam, K, 2018) |
| "The cancer chemotherapeutic potential of surfactant-cobalt(III) complexes, cis-[Co(bpy)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (1) and cis-[Co(phen)(2)(C(14)H(29)NH(2))Cl](ClO(4))(2)·3 H(2)O (2) (bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline) on MCF-7 breast cancer cell was determined adopting MTT assay and specific staining techniques." | 3.77 | Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line. ( Akbarsha, MA; Arunachalam, S; Dinesh, M; Krishnamurthy, H; Kumar, RS; Paul, CP; Riyasdeen, A; Srinag, S, 2011) |
| " We purified ADAM 12 from the urine of breast cancer patients via Q-Sepharose anion exchange and gelatin-Sepharose affinity chromatography followed by protein identification by matrix-assisted laser desorption/ionization-time of flight mass spectrometry." | 3.72 | ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage. ( Moses, MA; Pories, SE; Roy, R; Wewer, UM; Zurakowski, D, 2004) |
| "Cryosections of several breast cancer tissues were put on this gelatin film and incubated for 16 hrs at 37 degrees C." | 1.31 | Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography. ( Hara, Y; Iwase, H; Iwase, T; Iwata, H; Kobayashi, S; Miura, S; Mizutani, M; Nemori, R; Obata, Y; Omoto, Y; Toyama, T; Yamamoto, M; Yamashita, H, 2001) |
| "Treatment of human breast cancer cells with either H2O2 or hyperoxia increased the activity of spermidine/spermine N1-acetyltransferase (SSAT)." | 1.30 | Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species. ( Chopra, S; Wallace, HM, 1998) |
| "Our results indicate that human breast cancer cells contain a neutral phosphoramidon-sensitive metalloproteinase which can process big ET-1 to ET-1." | 1.29 | Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts. ( Patel, KV; Schrey, MP, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laws, K | 1 |
| Bineva-Todd, G | 1 |
| Eskandari, A | 1 |
| Lu, C | 1 |
| O'Reilly, N | 1 |
| Suntharalingam, K | 1 |
| Mohammadizadeh, F | 1 |
| Falahati-Pour, SK | 1 |
| Rezaei, A | 1 |
| Mohamadi, M | 1 |
| Hajizadeh, MR | 1 |
| Mirzaei, MR | 1 |
| Khoshdel, A | 1 |
| Fahmidehkar, MA | 1 |
| Mahmoodi, M | 1 |
| Alves, LN | 1 |
| Missailidis, S | 1 |
| Lage, CAS | 1 |
| DE Almeida, CEB | 1 |
| Zhang, Z | 1 |
| Wang, H | 2 |
| Wang, Q | 1 |
| Yan, M | 1 |
| Bi, C | 1 |
| Sun, S | 1 |
| Fan, Y | 1 |
| Kim, DH | 1 |
| Kim, JH | 1 |
| Kim, EH | 1 |
| Na, HK | 1 |
| Cha, YN | 1 |
| Chung, JH | 1 |
| Surh, YJ | 1 |
| Bandarra, D | 1 |
| Lopes, M | 1 |
| Lopes, T | 1 |
| Almeida, J | 1 |
| Saraiva, MS | 1 |
| Vasconcellos-Dias, M | 1 |
| Nunes, CD | 1 |
| Félix, V | 1 |
| Brandão, P | 1 |
| Vaz, PD | 1 |
| Meireles, M | 1 |
| Calhorda, MJ | 1 |
| Chin, LF | 1 |
| Kong, SM | 1 |
| Seng, HL | 1 |
| Khoo, KS | 1 |
| Vikneswaran, R | 1 |
| Teoh, SG | 1 |
| Ahmad, M | 1 |
| Khoo, SB | 1 |
| Maah, MJ | 1 |
| Ng, CH | 1 |
| Kumar, RS | 1 |
| Riyasdeen, A | 1 |
| Dinesh, M | 1 |
| Paul, CP | 1 |
| Srinag, S | 1 |
| Krishnamurthy, H | 1 |
| Arunachalam, S | 1 |
| Akbarsha, MA | 1 |
| Roy, R | 1 |
| Wewer, UM | 1 |
| Zurakowski, D | 1 |
| Pories, SE | 1 |
| Moses, MA | 1 |
| Patel, KV | 1 |
| Schrey, MP | 1 |
| Dinda, S | 1 |
| Kodali-Gali, S | 1 |
| Sevilla, L | 1 |
| Burkley, M | 1 |
| Hurd, C | 1 |
| Moudgil, VK | 1 |
| Chopra, S | 1 |
| Wallace, HM | 1 |
| Iwata, H | 1 |
| Yamamoto, M | 1 |
| Nemori, R | 1 |
| Mizutani, M | 1 |
| Iwase, T | 1 |
| Miura, S | 1 |
| Obata, Y | 1 |
| Hara, Y | 1 |
| Omoto, Y | 1 |
| Toyama, T | 1 |
| Yamashita, H | 1 |
| Iwase, H | 1 |
| Kobayashi, S | 1 |
13 other studies available for 1,10-phenanthroline and Breast Cancer
| Article | Year |
|---|---|
A Copper(II) Phenanthroline Metallopeptide That Targets and Disrupts Mitochondrial Function in Breast Cancer Stem Cells.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coordination Co | 2018 |
The cytotoxicity effects of a novel Cu complex on MCF-7 human breast cancerous cells.
Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Coordination Complexes; Copper; Fema | 2018 |
Anti-MUC1 Aptamer as Carrier Tool of the Potential Radiosensitizer 1,10 Phenanthroline in MCF-7 Breast Cancer Cells.
Topics: Aptamers, Nucleotide; Breast Neoplasms; Drug Carriers; Endocytosis; Feasibility Studies; Female; Fer | 2019 |
Anticancer activity and computational modeling of ternary copper (II) complexes with 3-indolecarboxylic acid and 1,10-phenanthroline.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Copper; Female; Humans; Indoles; | 2016 |
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
Topics: Breast Neoplasms; Cell Movement; Heme Oxygenase-1; Humans; Immunologic Factors; Iron; Iron Chelating | 2009 |
Mo(II) complexes: a new family of cytotoxic agents?
Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dos | 2010 |
Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chelating Agents; Cobalt; | 2011 |
Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line.
Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tu | 2011 |
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
Topics: ADAM Proteins; ADAM12 Protein; Adult; Aged; Amino Acid Sequence; Animals; Blotting, Western; Breast | 2004 |
Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts.
Topics: Aspartic Acid Endopeptidases; Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Cultur | 1995 |
Inhibition of proliferation of T47D human breast cancer cells: alterations in progesterone receptor and p53 tumor suppressor protein.
Topics: Antineoplastic Agents; Aurintricarboxylic Acid; Blotting, Western; Breast Neoplasms; Cell Division; | 1997 |
Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species.
Topics: Acetyltransferases; Breast Neoplasms; Free Radical Scavengers; Free Radicals; Humans; Hyperoxia; Iro | 1998 |
Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.
Topics: Azo Compounds; Breast Neoplasms; Cell Nucleus; Enzyme Inhibitors; Gelatin; Gelatinases; Hematoxylin; | 2001 |