1,10-phenanthroline has been researched along with Benign Neoplasms in 20 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
| Excerpt | Relevance | Reference |
|---|---|---|
| "Complex (1) displayed potent anticancer activity against B16 (Melanoma), MDA-MB-32 (Breast Adenocarcinoma), A549 (Lung Adenocarcinoma), HT-29 (Colon Adenocarcinoma) and SF (Astrocytoma) cell lines with an average IC50 value of 0." | 1.42 | Magnetic property, DFT calculation, and biological activity of bis[(μ(2)-chloro)chloro(1,10-phenanthroline)copper(II)] complex. ( Choi, ES; Daher, C; Demirdjian, S; Hammud, HH; Hariri, E; Isber, S; Mirtamizdoust, B; Mroueh, M, 2015) |
| "The anticancer activities of copper(II) complexes with phdpa and phen based ligands are correlated to their binding constants with DNA, but phen-based copper(II) complexes did not cause the nucleus fragmentation of HeLa cells." | 1.37 | Interaction with DNA and different effect on the nucleus of cancer cells for copper(II) complexes of N-benzyl di(pyridylmethyl)amine. ( Chen, QY; Fu, HJ; Gao, J; Ma, ZP; Qi, Y; Zhao, KD; Zhu, WH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 14 (70.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonetti, L | 1 |
| Barello, S | 1 |
| Franzoso-Sartorio, C | 1 |
| Rinaldi, MC | 1 |
| Cattaneo, A | 1 |
| Tolotti, A | 1 |
| Liptrott, S | 1 |
| Sari, D | 1 |
| Kostrhunova, H | 1 |
| McGhie, BS | 1 |
| Markova, L | 1 |
| Novakova, O | 1 |
| Kasparkova, J | 1 |
| Aldrich-Wright, JR | 1 |
| Brabec, V | 1 |
| Backman-Blanco, G | 1 |
| Valdés, H | 1 |
| Ramírez-Apan, MT | 1 |
| Cano-Sanchez, P | 1 |
| Hernandez-Ortega, S | 1 |
| Orjuela, AL | 1 |
| Alí-Torres, J | 1 |
| Flores-Gaspar, A | 1 |
| Reyes-Martínez, R | 1 |
| Morales-Morales, D | 1 |
| Kashanian, S | 1 |
| Khodaei, MM | 1 |
| Roshanfekr, H | 1 |
| Peyman, H | 1 |
| Lin, GJ | 1 |
| Jiang, GB | 1 |
| Xie, YY | 1 |
| Huang, HL | 2 |
| Liang, ZH | 1 |
| Liu, YJ | 2 |
| Liao, X | 2 |
| Lu, J | 2 |
| Ying, P | 2 |
| Zhao, P | 1 |
| Bai, Y | 1 |
| Li, W | 1 |
| Liu, M | 1 |
| İnci, D | 1 |
| Aydın, R | 1 |
| Yılmaz, D | 1 |
| Gençkal, HM | 1 |
| Vatan, Ö | 1 |
| Çinkılıç, N | 1 |
| Zorlu, Y | 1 |
| Zeng, P | 1 |
| Chen, H | 1 |
| Yang, N | 1 |
| Mroueh, M | 1 |
| Daher, C | 1 |
| Hariri, E | 1 |
| Demirdjian, S | 1 |
| Isber, S | 1 |
| Choi, ES | 1 |
| Mirtamizdoust, B | 1 |
| Hammud, HH | 1 |
| Zeng, CH | 1 |
| Yao, JH | 1 |
| Wu, FH | 1 |
| He, LX | 1 |
| Bandarra, D | 1 |
| Lopes, M | 1 |
| Lopes, T | 1 |
| Almeida, J | 1 |
| Saraiva, MS | 1 |
| Vasconcellos-Dias, M | 1 |
| Nunes, CD | 1 |
| Félix, V | 1 |
| Brandão, P | 1 |
| Vaz, PD | 1 |
| Meireles, M | 1 |
| Calhorda, MJ | 1 |
| Chen, QY | 1 |
| Fu, HJ | 1 |
| Zhu, WH | 1 |
| Qi, Y | 1 |
| Ma, ZP | 1 |
| Zhao, KD | 1 |
| Gao, J | 1 |
| Buchtík, R | 1 |
| Trávníček, Z | 1 |
| Vančo, J | 1 |
| Herchel, R | 1 |
| Dvořák, Z | 1 |
| Bortolotto, T | 1 |
| Silva, PP | 1 |
| Neves, A | 1 |
| Pereira-Maia, EC | 1 |
| Terenzi, H | 1 |
| Gao, E | 1 |
| Guan, F | 1 |
| Gao, X | 1 |
| Zhu, M | 1 |
| Liu, L | 1 |
| Wang, C | 1 |
| Zhang, W | 1 |
| Sun, Y | 1 |
| Tan, L | 1 |
| Shen, J | 1 |
| Liu, J | 1 |
| Zeng, L | 1 |
| Jin, L | 1 |
| Weng, C | 1 |
| Zhang, Z | 1 |
| Bi, C | 1 |
| Schmitt, SM | 1 |
| Fan, Y | 1 |
| Dong, L | 1 |
| Zuo, J | 1 |
| Dou, QP | 1 |
| Harhaji, L | 1 |
| Vuckovic, O | 1 |
| Miljkovic, D | 1 |
| Stosic-Grujicic, S | 1 |
| Trajkovic, V | 1 |
| Zalit, I | 1 |
| Glass, GA | 1 |
| Stark, AA | 1 |
| Nagatsu, T | 1 |
| Sakai, T | 1 |
| Kojima, K | 1 |
| Araki, E | 1 |
| Sakakibara, S | 1 |
| Fukasawa, K | 1 |
| Harada, M | 1 |
1 trial available for 1,10-phenanthroline and Benign Neoplasms
| Article | Year |
|---|---|
Protocol for a pilot and feasibility study evaluating a complex nurse-led patient education intervention to promote cancer patient engagement in healthy lifestyle (O-PHE programme).
Topics: Adult; Feasibility Studies; Healthy Lifestyle; Humans; Neoplasms; Nurse's Role; Patient Education as | 2022 |
19 other studies available for 1,10-phenanthroline and Benign Neoplasms
| Article | Year |
|---|---|
Platinum(IV) Derivatives of [Pt(1
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Diclofenac; Ligand | 2023 |
Synthesis of Pt(II) complexes of the type [Pt(1,10-phenanthroline)(SArF
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Coordination Complexes; Crys | 2020 |
DNA interaction of [Cu(dmp)(phen-dion)] (dmp=4,7 and 2,9 dimethyl phenanthroline, phen-dion=1,10-phenanthroline-5,6-dion) complexes and DNA-based electrochemical biosensor using chitosan-carbon nanotubes composite film.
Topics: Antineoplastic Agents; Biosensing Techniques; Cell Line, Tumor; Cell Survival; Chitosan; Coordinatio | 2013 |
Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes.
Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Checkpoints; Cell Li | 2013 |
DNA binding, antitumor activities, and hydroxyl radical scavenging properties of novel oxovanadium (IV) complexes with substituted isoniazid.
Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Cycle; Cell Line, Tumor; Coo | 2013 |
New water-soluble copper (II) complexes including 4,7-dimethyl-1,10-phenanthroline and L-tyrosine: synthesis, characterization, DNA interactions and cytotoxicities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Copper; Crystallogra | 2015 |
New Oxidovanadium Complexes Incorporating Thiosemicarbazones and 1, 10-Phenanthroline Derivatives as DNA Cleavage, Potential Anticancer Agents, and Hydroxyl Radical Scavenger.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Cleavage; Free Radical Scavengers; | 2015 |
Magnetic property, DFT calculation, and biological activity of bis[(μ(2)-chloro)chloro(1,10-phenanthroline)copper(II)] complex.
Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Copper; Crystallography, X-Ray; Hal | 2015 |
Synthesis, structure, DNA-binding properties, and cytotoxicity of ruthenium(II) polypyridyl complexes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA; Humans; Models, Molecular; Molecular St | 2010 |
Mo(II) complexes: a new family of cytotoxic agents?
Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dos | 2010 |
Interaction with DNA and different effect on the nucleus of cancer cells for copper(II) complexes of N-benzyl di(pyridylmethyl)amine.
Topics: Amines; Antineoplastic Agents; Cell Line, Tumor; Cell Nucleus; Coordination Complexes; Copper; Cryst | 2011 |
Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(II) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone.
Topics: 2,2'-Dipyridyl; 4-Quinolones; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Copper; Crys | 2011 |
Photoinduced DNA cleavage promoted by two copper(II) complexes of tetracyclines and 1,10-phenanthroline.
Topics: Animals; Copper; DNA; DNA Cleavage; Humans; Intercalating Agents; Neoplasms; Organometallic Compound | 2011 |
Novel palladium(II) complexes containing a sulfur ligand: structure and biological activity on HeLa cells.
Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; DNA; HeLa Cells; Humans; Intercalating Agents; Lig | 2012 |
Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru(II) mixed-ligand complexes.
Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cell Survival; Coordination Complexes; DNA; | 2012 |
1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Copper; | 2012 |
Iron down-regulates macrophage anti-tumour activity by blocking nitric oxide production.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Survival; Cytotoxicity, Immunologic; Down-Regulation; En | 2004 |
The role of chelators in the catalysis of glutathione-gamma-glutamyl transpeptidase-dependent lipid peroxidation by transition metals.
Topics: Animals; Catalysis; Chelating Agents; Citric Acid; Copper; Ferrous Compounds; gamma-Glutamyltransfer | 1996 |
A sensitive and specific assay for dipeptidyl-aminopeptidase II in serum and tissues by liquid chromatography-fluorometry.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Coumarins; Dipeptides; Dipeptidyl-Peptidases a | 1985 |