1,10-phenanthroline has been researched along with Abnormalities, Autosome in 6 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment of CHO and mosquito cells with STZ produced a significant and dose-response increase in the yield of CAs as well as SCEs (p<0." | 1.31 | The effect of 1,10-phenanthroline on the chromosome damage and sister-chromatid exchanges induced by streptozotocin in mammalian and insect cells. ( Bianchi, MS; Bolzán, AD; González, MC, 2000) |
| "Phenolphthalein did not produce DNA strand breaks in rat hepatocytes or DNA adducts in Chinese hamster ovary (CHO) cells." | 1.31 | Induction of chromosome aberrations in vitro by phenolphthalein: mechanistic studies. ( Armstrong, MJ; Galloway, SM; Gara, JP; Gealy, R; Greenwood, SK; Hilliard, CA; Laws, GM, 2000) |
| "When CHO cells were exposed to SN, chromosomal aberrations (CAs) and sister-chromatid exchanges (SCEs) were formed in a dose-dependent manner (P < 0." | 1.31 | Modulation of streptonigrin's clastogenic effects in CHO cells by the metal-chelating agent 1,10-phenanthroline. ( Bianchi, MS; Bolzán, AD; Correa, MV, 2001) |
| "Chromosomal aberrations are a secondary effect resulting from DNA cleavage." | 1.28 | Effect of the metal chelating agent o-phenanthroline on the DNA and chromosome damage induced by bleomycin in Chinese hamster ovary cells. ( Bianchi, NO; Larramendy, ML; López-Larraza, D; Vidal-Rioja, L, 1989) |
| "The production of chromosome aberrations by cyanide proved to be practically unaffected by the temperature during treatment." | 1.24 | Experimentally induced chromosome aberrations in plants. I. The production of chromosome aberrations by cyanide and other heavy metal complexing agents. ( KIHLMAN, BA, 1957) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KIHLMAN, BA | 1 |
| Bolzán, AD | 2 |
| González, MC | 1 |
| Bianchi, MS | 2 |
| Armstrong, MJ | 1 |
| Gara, JP | 1 |
| Gealy, R | 1 |
| Greenwood, SK | 1 |
| Hilliard, CA | 1 |
| Laws, GM | 1 |
| Galloway, SM | 1 |
| Correa, MV | 1 |
| Gille, JJ | 1 |
| van Berkel, CG | 1 |
| Joenje, H | 1 |
| Larramendy, ML | 1 |
| López-Larraza, D | 1 |
| Vidal-Rioja, L | 1 |
| Bianchi, NO | 1 |
6 other studies available for 1,10-phenanthroline and Abnormalities, Autosome
| Article | Year |
|---|---|
Experimentally induced chromosome aberrations in plants. I. The production of chromosome aberrations by cyanide and other heavy metal complexing agents.
Topics: Caffeine; Catalase; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Coordination Complexe | 1957 |
The effect of 1,10-phenanthroline on the chromosome damage and sister-chromatid exchanges induced by streptozotocin in mammalian and insect cells.
Topics: Animals; Cell Cycle; Cell Line; Chelating Agents; CHO Cells; Chromosome Aberrations; Cricetinae; Cyt | 2000 |
Induction of chromosome aberrations in vitro by phenolphthalein: mechanistic studies.
Topics: Animals; Antioxidants; Cathartics; Cell Line; Chelating Agents; CHO Cells; Chromosome Aberrations; C | 2000 |
Modulation of streptonigrin's clastogenic effects in CHO cells by the metal-chelating agent 1,10-phenanthroline.
Topics: Animals; Antibiotics, Antineoplastic; Chelating Agents; CHO Cells; Chromosome Aberrations; Cricetina | 2001 |
Effect of iron chelators on the cytotoxic and genotoxic action of hyperoxia in Chinese hamster ovary cells.
Topics: Animals; Cell Survival; CHO Cells; Chromosome Aberrations; Cricetinae; Deferoxamine; Hydrogen Peroxi | 1992 |
Effect of the metal chelating agent o-phenanthroline on the DNA and chromosome damage induced by bleomycin in Chinese hamster ovary cells.
Topics: Animals; Bleomycin; Cell Cycle; Cell Line; Chelating Agents; Chromosome Aberrations; Cricetinae; DNA | 1989 |