1-1-diphenyl-2-picrylhydrazyl has been researched along with Tongue-Neoplasms* in 2 studies
2 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and Tongue-Neoplasms
| Article | Year |
|---|---|
Cytotoxic activity of strawberry tree (
Strawberry tree (. Med obične planike ( Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Caco-2 Cells; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Chromans; Colorectal Neoplasms; Ericaceae; Gallic Acid; Hep G2 Cells; Homogentisic Acid; Honey; Humans; Iron; Liver Neoplasms; Phenols; Picrates; Plant Extracts; Reactive Oxygen Species; Tongue Neoplasms; Trees | 2022 |
Platinum nanocolloid-supplemented hydrogendissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells.
Hydrogen-dissolved water (HD-water) or platinum nanocolloid (Pt-nc) has been individually expected as a new therapeutic agent for oxidative stress-related diseases, whereas little is known about their combined effects on cancer, which were elucidated in the present study.. HD-water was prepared by microporous gas bubbling, and supplemented with Pt-nc consisting of 0.003-1 ppm Pt and PVP polymers. Antioxidant activities were examined by 1, 1-diphenyl-picrylhydrazyl (DPPH)-radicalscavenging assay. Cytotoxic activities were examined by culturing of tumor and normal cell lines, respectively.. HD-water accelerated the Pt-nc-based DPPH-radical scavenging. Pt-nc-supplemented HD-water inhibited either colony formation efficiencies or colony sizes of human tongue carcinoma cells HSC-4, in contrast to no effects of HD-water alone, Pt-nc alone or Pt-absent PVP, but not appreciably inhibit normal human tongue epithelial-like cells DOK. Pt-nc-supplemented HD-water also suppressed cell population growth of HSC-4 cells of near-confluence (at higher cell densities) in view of decreases in either cell numbers or mitochondrial function, although less markedly than colony formation starting from a sparse-cell state (at lower cell densities). Dissolved hydrogen, oxygen concentration or oxido-reduced potentials of HD-water was decreased, rather decreased or increased by Pt-nc addition, respectively.. Anti-cancer activity of Pt-nc-supplemented HD-water was shown by its preferential cell-growth inhibition to human tongue carcinoma cells HSC-4 over normal human tongue cells DOK, and might be partly attributed to HD-water-caused enhancement of Pt-nc-relevant antioxidant ability. Pt-nc-supplemented HD-water is expected as a novel agent against human tongue cancers due to its cancer progression-repressive abilities. Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Proliferation; Cell Survival; Colloids; Colony-Forming Units Assay; Free Radical Scavengers; Humans; Hydrogen; Metal Nanoparticles; Picrates; Platinum; Tongue Neoplasms; Water | 2009 |