Compounds > 1-1-diphenyl-2-picrylhydrazyl

1-1-diphenyl-2-picrylhydrazyl and Sarcoma

1-1-diphenyl-2-picrylhydrazyl has been researched along with Sarcoma* in 1 studies

Other Studies

1 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and Sarcoma

Article	Year
Evaluation of radicals scavenging, immunity-modulatory and antitumor activities of longan polysaccharides with ultrasonic extraction on in S180 tumor mice models. International journal of biological macromolecules, 2010, Oct-01, Volume: 47, Issue:3 Longan (Dimocarpus longan Lour.) is used as a traditional edible and medicinal material in China. In this paper, the effects of polysaccharides from longan pulp with ultrasonic extraction (UELP) on the radicals scavenging, immunity-modulatory and antitumor activities in S180 tumor mice models were investigated. UELP showed excellent scavenging activity on the hydroxyl radicals and a,a-diphenyl-1-picrylhydrazyl (DPPH) radicals, and obtained the almost complete scavenging effect. UELP with medium-dose (200mg/kg) and low-dose (100mg/kg) had potent immune-modulatory effects in S180 tumor mice model and exhibited significant effect on delayed-type hypersensitivity (DTH) response, macrophage phagocytosis and ConA-stimulated splenocyte proliferation as compared with model control treatment (p<0.01). The results still showed that UELP had great antitumor effects, and maximum inhibition rate was obtained at medium-dose and low-dose (200 and 100mg/kg). Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chemical Fractionation; Female; Free Radical Scavengers; Fruit; Hydroxyl Radical; Hypersensitivity, Delayed; Immunologic Factors; Lymphocytes; Macrophages, Peritoneal; Mice; Phagocytosis; Picrates; Polysaccharides; Sapindaceae; Sarcoma; Spleen; Ultrasonics	2010

Article

Year

Evaluation of radicals scavenging, immunity-modulatory and antitumor activities of longan polysaccharides with ultrasonic extraction on in S180 tumor mice models.

International journal of biological macromolecules, 2010, Oct-01, Volume: 47, Issue:3

Longan (Dimocarpus longan Lour.) is used as a traditional edible and medicinal material in China. In this paper, the effects of polysaccharides from longan pulp with ultrasonic extraction (UELP) on the radicals scavenging, immunity-modulatory and antitumor activities in S180 tumor mice models were investigated. UELP showed excellent scavenging activity on the hydroxyl radicals and a,a-diphenyl-1-picrylhydrazyl (DPPH) radicals, and obtained the almost complete scavenging effect. UELP with medium-dose (200mg/kg) and low-dose (100mg/kg) had potent immune-modulatory effects in S180 tumor mice model and exhibited significant effect on delayed-type hypersensitivity (DTH) response, macrophage phagocytosis and ConA-stimulated splenocyte proliferation as compared with model control treatment (p<0.01). The results still showed that UELP had great antitumor effects, and maximum inhibition rate was obtained at medium-dose and low-dose (200 and 100mg/kg).

Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chemical Fractionation; Female; Free Radical Scavengers; Fruit; Hydroxyl Radical; Hypersensitivity, Delayed; Immunologic Factors; Lymphocytes; Macrophages, Peritoneal; Mice; Phagocytosis; Picrates; Polysaccharides; Sapindaceae; Sarcoma; Spleen; Ultrasonics

2010