Compounds > 1-1-diphenyl-2-picrylhydrazyl

1-1-diphenyl-2-picrylhydrazyl and Nervous-System-Diseases

1-1-diphenyl-2-picrylhydrazyl has been researched along with Nervous-System-Diseases* in 1 studies

Other Studies

1 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and Nervous-System-Diseases

ArticleYear
Computational and Pharmacological Investigation of (E)-2-(4-Methoxybenzylidene)Cyclopentanone for Therapeutic Potential in Neurological Disorders.
    Drug design, development and therapy, 2020, Volume: 14

    This study involved the computational and pharmacological evaluation of (E)-2-(4-methoxybenzylidene)cyclopentan-1-one (A2K10).. In silico studies were conducted through virtual screening. Morris water and Y-maze tests were conducted to evaluate Alzheimer's disease. Acute epilepsy haloperidol,and hyperalgesia were used to calculate the epilepsy model, with Parkinson's disease and mechanical allodynia at a dose of 1-10 mg/kg in the mouse model.. Overall, the results indicated that A2K10 has potential as an anti-Alzheimer's, antiepileptic, antiparkinsonian, and analgesic therapeutic compound.

    Topics: Animals; Antioxidants; Biphenyl Compounds; Female; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Nervous System Diseases; Neuroprotective Agents; Picrates

2020