1-1-diphenyl-2-picrylhydrazyl has been researched along with Helicobacter-Infections* in 2 studies
2 other study(ies) available for 1-1-diphenyl-2-picrylhydrazyl and Helicobacter-Infections
| Article | Year |
|---|---|
Eradication of Helicobacter pylori through the inhibition of urease and peptide deformylase: Computational and biological studies.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Biphenyl Compounds; Cell Death; Chick Embryo; Chorioallantoic Membrane; Computational Biology; Diospyros; Free Radical Scavengers; Free Radicals; Gas Chromatography-Mass Spectrometry; Helicobacter Infections; Helicobacter pylori; Hydrogen Peroxide; Inhibitory Concentration 50; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; NIH 3T3 Cells; Nitric Oxide; Picrates; Plant Extracts; Urease | 2019 |
Treatment of Helicobacter pylori infected mice with Bryophyllum pinnatum, a medicinal plant with antioxidant and antimicrobial properties, reduces bacterial load.
Bryophyllum pinnatum (Lam.) Kurz (Crassulaceae) is a plant known for its antiulcer properties.. This study evaluates the anti-Helicobacter pylori activity of Bryophyllum pinnutum methanol extract with a mouse model and its antioxidant properties.. Dried leaves of Bryophyllum pinnutum were extracted with methanol and ethyl acetate. Broth microdilution method was used to evaluate the anti-Helicobacter activity of extract samples in vitro. Swiss mice were inoculated with a suspension of Helicobacter pylori and divided into control group and four others that received 125, 250, 500 mg/kg of methanol extract or ciprofloxacin (500 mg/kg), respectively, for 7 days. Helicobacter pylori colonization and bacterial load of mouse stomach was assessed on day 1 and 7 post-treatment. The antioxidant activity of Bryophyllum pinnutum was evaluated through DPPH radical, hydroxyl radical and reducing power assay.. The data suggest that the methanol extract of Bryophyllum pinnatum could inhibit Helicobacter pylori growth, and may also acts as an antioxidant to protect gastric mucosa against reactive oxygen species. Topics: Animals; Anti-Bacterial Agents; Antioxidants; Bacterial Load; Biphenyl Compounds; Disease Models, Animal; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Hydroxyl Radical; Kalanchoe; Methanol; Mice; Microbial Sensitivity Tests; Oxidation-Reduction; Phytotherapy; Picrates; Plant Extracts; Plant Leaves; Plants, Medicinal; Solvents; Time Factors | 2017 |