Page last updated: 2024-09-02

1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol and Acute Brain Injuries

1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol has been researched along with Acute Brain Injuries in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kompanje, EJ; Maas, AI; Murray, GD; Ohman, J; Slieker, FJ; Stocchetti, N; Teasdale, SG1
Nimmo, AJ; Vink, R1
Butcher, I; Lecky, FE; Lingsma, HF; Lu, J; Maas, AI; McHugh, GS; Murray, GD; Perel, P; Roozenbeek, B; Steyerberg, EW; Weir, J1
Van Den Heuvel, C; Vink, R1
Guha, A1
Henney, H; Kassem, N; Knoller, N; Legrand, V; Maas, AI; Mangelus, M; Muizelaar, JP; Murray, G; Stocchetti, N1
Biegon, A; Joseph, AB1
Belkin, M; Schwartz, M; Yoles, E1
Bass, R; Ben-Hur, T; Gallily, R; Mechoulam, R; Shohami, E1
Mechoulam, R; Panikashvili, D; Shohami, E1
Bedell, EA; Prough, DS1

Reviews

5 review(s) available for 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol and Acute Brain Injuries

ArticleYear
Multifunctional drugs for head injury.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2009, Volume: 6, Issue:1

    Topics: Animals; Brain Edema; Brain Injuries; Cyclosporine; Dronabinol; Erythropoietin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinins; Magnesium; Minocycline; Mitochondria; Neuroprotective Agents; Oxidative Stress; Progesterone; Psychotropic Drugs; Thyrotropin-Releasing Hormone; Toll-Like Receptors

2009
Recent advances in the development of multifactorial therapies for the treatment of traumatic brain injury.
    Expert opinion on investigational drugs, 2004, Volume: 13, Issue:10

    Topics: Animals; Brain Injuries; Cyclosporine; Dexamethasone; Dronabinol; Humans; Magnesium; Mitochondria; Neuroprotective Agents; Oxidative Stress; Progesterone

2004
Management of traumatic brain injury: some current evidence and applications.
    Postgraduate medical journal, 2004, Volume: 80, Issue:949

    Topics: Absorptiometry, Photon; Anti-Inflammatory Agents; Barbiturates; Brain Injuries; Clinical Trials as Topic; Diuretics, Osmotic; Dronabinol; Humans; Hydrostatic Pressure; Hypothermia; Mannitol; Neuromuscular Blockade; Neuroprotective Agents; Osmotic Pressure; Sodium Chloride

2004
Development of HU-211 as a neuroprotectant for ischemic brain damage.
    Neurological research, 1995, Volume: 17, Issue:4

    Topics: Animals; Brain Injuries; Brain Ischemia; Dronabinol; Excitatory Amino Acid Antagonists; Gerbillinae; Head Injuries, Closed; Neuroprotective Agents; Rats; Receptors, N-Methyl-D-Aspartate

1995
Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant.
    Journal of neuroimmunology, 1997, Volume: 72, Issue:2

    Topics: Animals; Brain; Brain Injuries; Cytokines; Dronabinol; Excitatory Amino Acid Antagonists; Head Injuries, Closed; Neuroprotective Agents; Tumor Necrosis Factor-alpha

1997

Trials

2 trial(s) available for 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol and Acute Brain Injuries

ArticleYear
Importance of screening logs in clinical trials for severe traumatic brain injury.
    Neurosurgery, 2008, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Injuries; Dronabinol; Feasibility Studies; Forms and Records Control; Humans; Medical Records; Middle Aged; Neuroprotective Agents; Outcome Assessment, Health Care; Patient Selection; Piperazines

2008
Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial.
    The Lancet. Neurology, 2006, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Injuries; Chi-Square Distribution; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Intracranial Pressure; Male; Middle Aged; Neuroprotective Agents; Odds Ratio; Quality of Life; Retrospective Studies; Time Factors; Treatment Outcome

2006

Other Studies

4 other study(ies) available for 1,1-dimethylheptyl-11-hydroxytetrahydrocannabinol and Acute Brain Injuries

ArticleYear
Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic mod
    Critical care medicine, 2012, Volume: 40, Issue:5

    Topics: Apolipoproteins E; Brain Injuries; Dronabinol; Glasgow Outcome Scale; Guanidines; Humans; Hypothermia, Induced; Logistic Models; Models, Statistical; Neuroprotective Agents; Prognosis; Registries; ROC Curve

2012
HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy.
    Journal of neurotrauma, 1996, Volume: 13, Issue:1

    Topics: Action Potentials; Animals; Axons; Brain Injuries; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Electrophysiology; Energy Metabolism; Evoked Potentials, Visual; Male; NAD; Nerve Crush; Neuroprotective Agents; Optic Nerve; Optic Nerve Injuries; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Time Factors

1996
Cannabinoids and brain injury: therapeutic implications.
    Trends in molecular medicine, 2002, Volume: 8, Issue:2

    Topics: Animals; Arachidonic Acids; Brain; Brain Injuries; Cannabinoid Receptor Modulators; Cannabinoids; Clinical Trials, Phase III as Topic; Dronabinol; Endocannabinoids; Glycerides; Humans; Neuroprotective Agents; Pain; Polyunsaturated Alkamides; Rats

2002
Dexanabinol as a treatment for traumatic brain injury: will another therapeutic promise be broken?
    Critical care medicine, 2002, Volume: 30, Issue:3

    Topics: Brain Injuries; Clinical Trials, Phase II as Topic; Dronabinol; Humans; Neuroprotective Agents

2002