1-1-dimethylallyl-caffeic-acid-ester has been researched along with Dermatitis--Contact* in 2 studies
2 other study(ies) available for 1-1-dimethylallyl-caffeic-acid-ester and Dermatitis--Contact
| Article | Year |
|---|---|
Propolis allergy: synthesis and patch testing of gamma,gamma-dimethylallyl caffeic acid ester and its o-methyl derivatives.
Topics: Caffeic Acids; Cinnamates; Dermatitis, Contact; Humans; Patch Tests; Propolis; Resins, Plant | 1989 |
Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester.
As shown in the preceding paper, propolis or bee-glue is the cause of an increasing number of allergic reactions in persons using it in external preparations and cosmetics. Propolis and its main contact allergen, 1,1-dimethylallyl caffeic acid ester, designated LB-1, show strong sensitizing properties in patients as well as in guinea pig experiments. 9 patients have been patch tested with this compound, 8 of whom reacted strongly. Chemical separation of different propolis samples and poplar bud extracts reveal that LB-1 is always present. Poplar bud secretion is the bee's major source for propolis and hence the origin of LB-1. A warning is indicated, in agreement with several other authors, that propolis should not be used in topical products because of its strong sensitizing properties. Topics: Adult; Aged; Aged, 80 and over; Animals; Caffeic Acids; Cinnamates; Dermatitis, Contact; Female; Guinea Pigs; Humans; Immunization; Male; Middle Aged; Patch Tests; Plant Extracts; Plants, Medicinal; Propolis; Resins, Plant | 1987 |