1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Vitreoretinopathy, Proliferative in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Vitreoretinopathy, Proliferative: Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kita, T | 2 |
| Hata, Y | 1 |
| Arita, R | 1 |
| Kawahara, S | 1 |
| Miura, M | 1 |
| Nakao, S | 1 |
| Mochizuki, Y | 1 |
| Enaida, H | 1 |
| Goto, Y | 1 |
| Shimokawa, H | 1 |
| Hafezi-Moghadam, A | 1 |
| Ishibashi, T | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
[Molecular mechanisms of preretinal membrane contraction in proliferative vitreoretinal diseases and ROCK as a therapeutic target].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diabetic Retinopathy; Molecular Targeted The | 2010 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Blotting, Western; Immunohistochemis | 2008 |