1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Urinary Bladder Neoplasms in 6 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arsenic trioxide (ATO) is a potent antitumor agent used to treat acute promyelocytic leukemia, and recently solid tumors including bladder cancers." | 7.75 | Protein kinase C is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in human bladder cancer cells. ( An, R; Dong, X; Duan, G; Pan, S; Sun, X; Wang, Y, 2009) |
| "Arsenic trioxide (ATO) is a potent antitumor agent used to treat acute promyelocytic leukemia, and recently solid tumors including bladder cancers." | 3.75 | Protein kinase C is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in human bladder cancer cells. ( An, R; Dong, X; Duan, G; Pan, S; Sun, X; Wang, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woldu, SL | 1 |
| Hutchinson, RC | 1 |
| Krabbe, LM | 1 |
| Sanli, O | 1 |
| Margulis, V | 1 |
| Abe, H | 1 |
| Kamai, T | 1 |
| Hayashi, K | 1 |
| Anzai, N | 1 |
| Shirataki, H | 1 |
| Mizuno, T | 1 |
| Yamaguchi, Y | 1 |
| Masuda, A | 1 |
| Yuki, H | 1 |
| Betsunoh, H | 1 |
| Yashi, M | 1 |
| Fukabori, Y | 1 |
| Yoshida, K | 1 |
| Wang, Y | 1 |
| An, R | 1 |
| Dong, X | 1 |
| Pan, S | 1 |
| Duan, G | 1 |
| Sun, X | 1 |
| Koike, K | 1 |
| Uchiumi, T | 1 |
| Ohga, T | 1 |
| Toh, S | 1 |
| Wada, M | 1 |
| Kohno, K | 1 |
| Kuwano, M | 1 |
| Zhang, Y | 1 |
| Mahendran, R | 1 |
| Yap, LL | 1 |
| Esuvaranathan, K | 1 |
| Khoo, HE | 1 |
| Hubbell, HR | 1 |
| Boyer, JE | 1 |
| Roane, P | 1 |
| Burch, RM | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
The Rho GTPase signalling pathway in urothelial carcinoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Camellia sinensis; Carcinoma, Transitional Ce | 2018 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
The Rho-kinase inhibitor HA-1077 suppresses proliferation/migration and induces apoptosis of urothelial cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Prol | 2014 |
Protein kinase C is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in human bladder cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; A | 2009 |
Nuclear translocation of the Y-box binding protein by ultraviolet irradiation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; CCAAT-Enhancer-Binding Proteins; Cell Nucleu | 1997 |
The signalling pathway for BCG-induced interleukin-6 production in human bladder cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Antibodies; BCG Vaccine; Colforsin; Cyclic A | 2002 |
Cyclic AMP mediates the direct antiproliferative action of mismatched double-stranded RNA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Astrocytoma; Base Composition; Car | 1991 |