1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Triple Negative Breast Neoplasms in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Triple Negative Breast Neoplasms: Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Guerra, FS | 1 |
Oliveira, RG | 1 |
Fraga, CAM | 1 |
Mermelstein, CDS | 1 |
Fernandes, PD | 1 |
Fagan-Solis, KD | 1 |
Schneider, SS | 1 |
Pentecost, BT | 1 |
Bentley, BA | 1 |
Otis, CN | 1 |
Gierthy, JF | 1 |
Arcaro, KF | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Triple Negative Breast Neoplasms
Article | Year |
---|---|
ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Agents; beta Catenin; Carcinoma; Cell | 2017 |
The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Movement; Epithelial-Mesenchymal Transition; Fem | 2013 |