1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Shock, Septic in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gram-negative sepsis/septic shock in the newborn continues to be a major medical problem, causing high mortality." | 1.29 | Lipopolysaccharide alters suckling rat liver glycogenolysis. ( Goto, M; Goto, MP; Hurley, RM; Picken, M; Zeller, WP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ytrebo, LM | 1 |
| Goto, M | 1 |
| Zeller, WP | 1 |
| Picken, M | 1 |
| Goto, MP | 1 |
| Hurley, RM | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Shock, Septic
| Article | Year |
|---|---|
Vascular dysfunction in septic shock--any ROCKing news?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Disease Models, Animal; Endothelium, | 2009 |
Lipopolysaccharide alters suckling rat liver glycogenolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Cytarabine; Disease Models | 1993 |