1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Schizophrenia studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

Excerpt	Relevance	Reference
"Current antipsychotics used to treat schizophrenia have associated problems, including serious side effects and treatment resistance."	5.72	Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia. ( Kaibuchi, K; Liao, J; Liu, Y; Miyagawa, Y; Mizoguchi, H; Nagai, T; Ozaki, N; Sawahata, M; Sobue, A; Takase, S; Tanaka, R; Yamada, K, 2022)
"Current antipsychotics used to treat schizophrenia have associated problems, including serious side effects and treatment resistance."	1.72	Antipsychotic-like effects of fasudil, a Rho-kinase inhibitor, in a pharmacologic animal model of schizophrenia. ( Kaibuchi, K; Liao, J; Liu, Y; Miyagawa, Y; Mizoguchi, H; Nagai, T; Ozaki, N; Sawahata, M; Sobue, A; Takase, S; Tanaka, R; Yamada, K, 2022)

Research

Studies (1)

Authors

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Schizophrenia

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (100.00)	2.80

Authors	Studies
Takase, S	1
Liao, J	1
Liu, Y	1
Tanaka, R	1
Miyagawa, Y	1
Sawahata, M	1
Sobue, A	1
Mizoguchi, H	1
Nagai, T	1
Kaibuchi, K	1
Ozaki, N	1
Yamada, K	1