1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Right Ventricular Dysfunction in 4 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil was well tolerated; one patient discontinued treatment." | 5.42 | Intravenous fasudil improves in-hospital mortality of patients with right heart failure in severe pulmonary hypertension. ( Ai, ZS; Gomberg-Maitland, M; He, J; Jiang, R; Jiang, X; Jing, ZC; Liu, D; Wang, L; Yuan, P; Zhao, QH, 2015) |
| "Fasudil was well tolerated; one patient discontinued treatment." | 1.42 | Intravenous fasudil improves in-hospital mortality of patients with right heart failure in severe pulmonary hypertension. ( Ai, ZS; Gomberg-Maitland, M; He, J; Jiang, R; Jiang, X; Jing, ZC; Liu, D; Wang, L; Yuan, P; Zhao, QH, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gosal, K | 1 |
| Dunlop, K | 1 |
| Dhaliwal, R | 1 |
| Ivanovska, J | 2 |
| Kantores, C | 2 |
| Desjardins, JF | 1 |
| Connelly, KA | 1 |
| McNamara, PJ | 2 |
| Jain, A | 1 |
| Jankov, RP | 2 |
| Jiang, R | 1 |
| Ai, ZS | 1 |
| Jiang, X | 1 |
| Yuan, P | 1 |
| Liu, D | 1 |
| Zhao, QH | 1 |
| He, J | 1 |
| Wang, L | 1 |
| Gomberg-Maitland, M | 1 |
| Jing, ZC | 1 |
| Xu, EZ | 1 |
| Engelberts, D | 1 |
| Kavanagh, BP | 1 |
| Yasuda, T | 1 |
| Tada, Y | 1 |
| Tanabe, N | 1 |
| Tatsumi, K | 1 |
| West, J | 1 |
4 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Right Ventricular Dysfunction
| Article | Year |
|---|---|
Rho kinase mediates right ventricular systolic dysfunction in rats with chronic neonatal pulmonary hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cyclic Nucleotide Phosphodiesterases, Type 5 | 2015 |
Intravenous fasudil improves in-hospital mortality of patients with right heart failure in severe pulmonary hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Intravenous; Adult; Female; Heart Fai | 2015 |
Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Age Factors; Aging; Amides; Animals; Apoptosis; Cell | 2010 |
Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute-Phase Proteins; Animals; Blotting, Western; Bon | 2011 |