1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Parkinson Disease, Secondary in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, YH | 1 |
Yu, JW | 1 |
Xi, JY | 1 |
Yu, WB | 1 |
Liu, JC | 1 |
Wang, Q | 1 |
Song, LJ | 1 |
Feng, L | 1 |
Yan, YP | 1 |
Zhang, GX | 1 |
Xiao, BG | 1 |
Ma, CG | 1 |
Tönges, L | 1 |
Frank, T | 1 |
Tatenhorst, L | 1 |
Saal, KA | 1 |
Koch, JC | 1 |
Szego, ÉM | 1 |
Bähr, M | 1 |
Weishaupt, JH | 1 |
Lingor, P | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Parkinson Disease, Secondary
Article | Year |
---|---|
Fasudil Enhances Therapeutic Efficacy of Neural Stem Cells in the Mouse Model of MPTP-Induced Parkinson's Disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals | 2017 |
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-4-phenylpyridinium; Animals; Axons; Behavior | 2012 |