1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Pain in 3 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this article, the potential analgesic effects of Fasudil in a range of preclinical pain models were assessed." | 7.76 | Characterization of Fasudil in preclinical models of pain. ( Boyce-Rustay, JM; Chu, KL; Honore, P; McGaraughty, S; Simler, GH; Vasudevan, A; Wensink, EJ, 2010) |
| "In this article, the potential analgesic effects of Fasudil in a range of preclinical pain models were assessed." | 3.76 | Characterization of Fasudil in preclinical models of pain. ( Boyce-Rustay, JM; Chu, KL; Honore, P; McGaraughty, S; Simler, GH; Vasudevan, A; Wensink, EJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyce-Rustay, JM | 1 |
| Simler, GH | 1 |
| McGaraughty, S | 1 |
| Chu, KL | 1 |
| Wensink, EJ | 1 |
| Vasudevan, A | 1 |
| Honore, P | 1 |
| Tatsumi, S | 1 |
| Mabuchi, T | 1 |
| Katano, T | 1 |
| Matsumura, S | 1 |
| Abe, T | 1 |
| Hidaka, H | 1 |
| Suzuki, M | 1 |
| Sasaki, Y | 1 |
| Minami, T | 1 |
| Ito, S | 1 |
| Coderre, TJ | 1 |
| Yashpal, K | 1 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Pain
| Article | Year |
|---|---|
Characterization of Fasudil in preclinical models of pain.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics; Animals; Disease Models, Animal; Male; Pa | 2010 |
Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Enzyme Inh | 2005 |
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; F | 1994 |