1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Osteoarthritis in 4 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pernis, AB | 1 |
| Ricker, E | 1 |
| Weng, CH | 1 |
| Rozo, C | 1 |
| Yi, W | 1 |
| Haudenschild, DR | 1 |
| Nguyen, B | 1 |
| Chen, J | 1 |
| D'Lima, DD | 1 |
| Lotz, MK | 1 |
| Namazi, H | 1 |
| Richard, M | 1 |
| Broquet, P | 1 |
| Vignon, E | 1 |
| Peschard, MJ | 1 |
| Carret, JP | 1 |
| Louisot, P | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Osteoarthritis
| Article | Year |
|---|---|
Rho Kinases in Autoimmune Diseases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Arthritis, Rheumatoid; Autoimmune Di | 2016 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Osteoarthritis
| Article | Year |
|---|---|
Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Adolescent; Adult; Cell Culture Techniques; C | 2008 |
Fasudil: a potential addition to the anti-arthritis weaponry.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Humans; Middle Aged; Models, Biological; Osteoa | 2007 |
Calmodulin-dependent collagenase and proteoglycanase activities in chondrocytes from human osteoarthritic cartilage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calmodulin; Cartilage, Articular; Humans; In Vitro Te | 1991 |