1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Neuralgia in 2 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "post-treatment with fasudil, which possesses the inhibitory effect of several protein kinases including PKC and Rho kinase." | 1.34 | [Effects of fasudil on neuropathic pain-like state in mice]. ( Inoue, T; Miyoshi, K; Nagumo, Y; Narita, M; Okutsu, D; Shiokawa, M; Suzuki, M; Suzuki, T; Yamaguchi, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JH | 1 |
| Lee, GE | 1 |
| Lee, SD | 1 |
| Hien, TT | 1 |
| Kim, S | 1 |
| Yang, JW | 1 |
| Cho, JH | 1 |
| Ko, H | 1 |
| Lim, SC | 1 |
| Kim, YG | 1 |
| Kang, KW | 1 |
| Kim, YC | 1 |
| Shiokawa, M | 1 |
| Yamaguchi, T | 1 |
| Narita, M | 1 |
| Okutsu, D | 1 |
| Nagumo, Y | 1 |
| Miyoshi, K | 1 |
| Suzuki, M | 1 |
| Inoue, T | 1 |
| Suzuki, T | 1 |
2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Neuralgia
| Article | Year |
|---|---|
Discovery of novel 2,5-dioxoimidazolidine-based P2X(7) receptor antagonists as constrained analogues of KN62.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arthritis, Experimental; Carrageenan; Cattle | 2015 |
[Effects of fasudil on neuropathic pain-like state in mice].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Disease Models, Animal; Injections, Epidural | 2007 |