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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Myocarditis

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Myocarditis in 2 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether there exists a cardio-protective effect of Fasudil, a selective Rho kinase (ROCK) inhibitor, in an experimental murine model of acute viral myocarditis."7.88Fasudil exerts a cardio-protective effect on mice with coxsackievirus B3-induced acute viral myocarditis. ( Chen, Q; Dai, K; Kuver, A; Li, J; Lian, H; Liao, W; Ni, H; Tai, S; Wang, Y; Yu, Y; Zheng, C, 2018)
"To investigate whether there exists a cardio-protective effect of Fasudil, a selective Rho kinase (ROCK) inhibitor, in an experimental murine model of acute viral myocarditis."3.88Fasudil exerts a cardio-protective effect on mice with coxsackievirus B3-induced acute viral myocarditis. ( Chen, Q; Dai, K; Kuver, A; Li, J; Lian, H; Liao, W; Ni, H; Tai, S; Wang, Y; Yu, Y; Zheng, C, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dai, K1
Wang, Y1
Tai, S1
Ni, H1
Lian, H1
Yu, Y2
Liao, W1
Zheng, C1
Chen, Q1
Kuver, A1
Li, J1
Preau, S1
Delguste, F1
Remy-Jouet, I1
Richard, V1
Saulnier, F1
Boulanger, E1
Neviere, R1

Other Studies

2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Myocarditis

ArticleYear
Fasudil exerts a cardio-protective effect on mice with coxsackievirus B3-induced acute viral myocarditis.
    Cardiovascular therapeutics, 2018, Volume: 36, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents; Antiviral Agents;

2018
Endotoxemia Engages the RhoA Kinase Pathway to Impair Cardiac Function By Altering Cytoskeleton, Mitochondrial Fission, and Autophagy.
    Antioxidants & redox signaling, 2016, Apr-01, Volume: 24, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Depolymerizing Factors; Animals; Autophagy; Cal

2016