1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Myasthenia Gravis in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, J | 1 |
| Xi, JY | 1 |
| Yu, WB | 1 |
| Yan, C | 1 |
| Luo, SS | 1 |
| Zhou, L | 1 |
| Zhu, WH | 1 |
| Lu, JH | 1 |
| Dong, Q | 1 |
| Xiao, BG | 1 |
| Zhao, CB | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Myasthenia Gravis
| Article | Year |
|---|---|
Inhibition of ROCK activity regulates the balance of Th1, Th17 and Treg cells in myasthenia gravis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Disease Models, Animal; Fem | 2019 |