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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Malaria, Falciparum

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Malaria, Falciparum in 1 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research Excerpts

ExcerptRelevanceReference
"Fasudil was found to be able to prevent endothelium apoptosis from all the P."1.36Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria. ( Bisvigou, U; Lékana-Douki, JB; Lékoulou, F; Mazier, D; Taoufiq, Z; Touré-Ndouo, FS; Traoré, Y; Zang-Edou, ES, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zang-Edou, ES1
Bisvigou, U1
Taoufiq, Z1
Lékoulou, F1
Lékana-Douki, JB1
Traoré, Y1
Mazier, D1
Touré-Ndouo, FS1

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Malaria, Falciparum

ArticleYear
Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria.
    PloS one, 2010, Oct-07, Volume: 5, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Animals; Antimalarials; Apoptosis; Cell A

2010