1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Malaria, Falciparum in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil was found to be able to prevent endothelium apoptosis from all the P." | 1.36 | Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria. ( Bisvigou, U; Lékana-Douki, JB; Lékoulou, F; Mazier, D; Taoufiq, Z; Touré-Ndouo, FS; Traoré, Y; Zang-Edou, ES, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zang-Edou, ES | 1 |
| Bisvigou, U | 1 |
| Taoufiq, Z | 1 |
| Lékoulou, F | 1 |
| Lékana-Douki, JB | 1 |
| Traoré, Y | 1 |
| Mazier, D | 1 |
| Touré-Ndouo, FS | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Malaria, Falciparum
| Article | Year |
|---|---|
Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Animals; Antimalarials; Apoptosis; Cell A | 2010 |