1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with MPTP Neurotoxicity Syndrome in 3 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, YF | 1 |
| Zhang, Q | 1 |
| Xi, JY | 1 |
| Li, YH | 1 |
| Ma, CG | 1 |
| Xiao, BG | 1 |
| Tönges, L | 1 |
| Frank, T | 1 |
| Tatenhorst, L | 1 |
| Saal, KA | 1 |
| Koch, JC | 1 |
| Szego, ÉM | 1 |
| Bähr, M | 1 |
| Weishaupt, JH | 1 |
| Lingor, P | 1 |
| Barcia, C | 1 |
| Ros, CM | 1 |
| Annese, V | 1 |
| Carrillo-de Sauvage, MA | 1 |
| Ros-Bernal, F | 1 |
| Gómez, A | 1 |
| Yuste, JE | 1 |
| Campuzano, CM | 1 |
| de Pablos, V | 1 |
| Fernandez-Villalba, E | 1 |
| Herrero, MT | 1 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Multitarget intervention of Fasudil in the neuroprotection of dopaminergic neurons in MPTP-mouse model of Parkinson's disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Cytokines; Disease Mod | 2015 |
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-4-phenylpyridinium; Animals; Axons; Behavior | 2012 |
ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Animals; cdc42 GTP-Binding Protei | 2012 |