1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Limb-Girdle Muscular Dystrophies in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Excerpt | Relevance | Reference |
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"Fasudil treated SJL/J mice showed increased body weight, but decreased grip strength, horizontal activity, and soleus muscle force, compared to untreated SJL/J controls." | 1.36 | Characterization of dysferlin deficient SJL/J mice to assess preclinical drug efficacy: fasudil exacerbates muscle disease phenotype. ( Gordish-Dressman, H; Hoffman, EP; Knoblach, SM; Nagaraju, K; Rayavarapu, S; Van der Meulen, JH, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Rayavarapu, S | 1 |
Van der Meulen, JH | 1 |
Gordish-Dressman, H | 1 |
Hoffman, EP | 1 |
Nagaraju, K | 1 |
Knoblach, SM | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Limb-Girdle Muscular Dystrophies
Article | Year |
---|---|
Characterization of dysferlin deficient SJL/J mice to assess preclinical drug efficacy: fasudil exacerbates muscle disease phenotype.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Disease Models, Animal; Drug Evaluation, Pre | 2010 |