1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Leucocythaemia in 7 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a previous study, we showed that geranylgeraniol (GGO) is a potent inducer of apoptosis in human leukemia cells, including HL60 promyelocytic leukemia cells." | 7.69 | Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells. ( Aiuchi, T; Masuda, Y; Nakajo, S; Nakaya, K; Ohizumi, H; Watabe, M; Yoda, M, 1997) |
| "In a previous study, we showed that geranylgeraniol (GGO) is a potent inducer of apoptosis in human leukemia cells, including HL60 promyelocytic leukemia cells." | 3.69 | Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells. ( Aiuchi, T; Masuda, Y; Nakajo, S; Nakaya, K; Ohizumi, H; Watabe, M; Yoda, M, 1997) |
| "Injected human leukemic and breast cancer cells exhibited cell-type specific patterns of intravascular distribution with leukemic cells moving faster than breast cancer cells." | 1.56 | Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts. ( Asokan, N; Bernas, SN; Bornhäuser, M; Brand, M; Daetwyler, S; Huisken, J; Kempermann, G; Lambert, K; Schmied, C; Vogler, S; Wermke, M; Wobus, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Asokan, N | 1 |
| Daetwyler, S | 1 |
| Bernas, SN | 1 |
| Schmied, C | 1 |
| Vogler, S | 1 |
| Lambert, K | 1 |
| Wobus, M | 1 |
| Wermke, M | 1 |
| Kempermann, G | 1 |
| Huisken, J | 1 |
| Brand, M | 1 |
| Bornhäuser, M | 1 |
| Zhang, X | 1 |
| Meng, L | 1 |
| He, B | 1 |
| Chen, J | 1 |
| Liu, P | 1 |
| Zhao, J | 1 |
| Zhang, Y | 1 |
| Li, M | 1 |
| An, D | 1 |
| Jung, EY | 1 |
| Ohshima, Y | 1 |
| Shintaku, N | 1 |
| Sumimoto, S | 1 |
| Heike, T | 1 |
| Katamura, K | 1 |
| Mayumi, M | 1 |
| Masuda, Y | 1 |
| Yoda, M | 1 |
| Ohizumi, H | 1 |
| Aiuchi, T | 1 |
| Watabe, M | 1 |
| Nakajo, S | 1 |
| Nakaya, K | 1 |
| Koike, T | 1 |
| Harada, N | 1 |
| Yoshida, T | 1 |
| Morikawa, M | 1 |
| Meichle, A | 1 |
| Schütze, S | 1 |
| Hensel, G | 1 |
| Brunsing, D | 1 |
| Krönke, M | 1 |
| Spisani, S | 1 |
| Gavioli, R | 1 |
| Giuliani, AL | 1 |
| Traniello, S | 1 |
7 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Leucocythaemia
| Article | Year |
|---|---|
Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Tra | 2020 |
The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Apoptosis; Benzoxazoles; Biol | 2009 |
Effects of cyclic AMP on expression of LFA-1, Mac-1, and VLA-4 and eosinophilic differentiation of a human leukemia cell line, EoL-1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, CD; Bucladesine; Butyrates; Cell Differenti | 1994 |
Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Apoptosis; Diglycerides; Diterpen | 1997 |
Regulation of myeloid-specific calcium binding protein synthesis by cytosolic protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Calcitriol; Calcium-Bind | 1992 |
Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Binding Sites; Cell Line; D | 1990 |
Triggering of neutrophil cytotoxicity against an antibody-coated tumour target by TPA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antibody-Dependent Cell Cytot | 1989 |