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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Kidney Neoplasms

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Kidney Neoplasms in 5 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"This had not been analyzed for renal cell carcinomas (RCCs)."1.34Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway. ( Gobe, G; Johnson, DW; Li, J; Vesey, DA, 2007)
"Incubation of the human renal carcinoma cell line CaKi-1 with tumour necrosis factor alpha (TNF alpha) or the phorbol ester phorbol-12-myristate 13 acetate (PMA) strongly enhanced the immunocytochemical staining of the intercellular adhesion molecule ICAM-1, in a non-linear manner."1.29Comparison of the effects of tumour necrosis factor alpha stimulation and phorbol ester treatment on the immunocytochemical staining of intercellular adhesion molecule 1 in human renal carcinoma cell cultures. ( Andersen, CB; Hansen, AB, 1993)
"Incubation of the human renal carcinoma cell line CaKi-1 with interferon-gamma (IFN-gamma) or the phorbol ester, phorbol-12-myristate 13-acetate (PMA) strongly stimulated the immunocytochemical expression of the intercellular adhesion molecule-1 (ICAM-1) in a dose-dependent manner."1.29Role of protein kinase C during interferon-gamma- and phorbol ester-stimulated immunocytochemical expression of ICAM-1 in human renal carcinoma cells. ( Andersen, CB; Bouchelouche, PN; Giese, BN; Hansen, AB, 1993)
"A cell line (SMKT-R3) established from renal cell carcinoma was characterized by sulfolipids and glycolipid sulfotransferases."1.28[Sulfolipids and glycolipid sulfotransferases in a human renal cell carcinoma cell line]. ( Kobayashi, T, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, J1
Vesey, DA1
Johnson, DW1
Gobe, G1
Hansen, AB2
Andersen, CB2
Bouchelouche, PN1
Giese, BN1
Kobayashi, T1
Nygren, P1
Larsson, R1

Other Studies

5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Kidney Neoplasms

ArticleYear
Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway.
    Cancer biology & therapy, 2007, Volume: 6, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anemia; Apoptosis; Carcinoma, Renal Cell; Cell Line,

2007
Comparison of the effects of tumour necrosis factor alpha stimulation and phorbol ester treatment on the immunocytochemical staining of intercellular adhesion molecule 1 in human renal carcinoma cell cultures.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1993, Volume: 63, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Carcinoma, Renal Cell; Cell Ad

1993
Role of protein kinase C during interferon-gamma- and phorbol ester-stimulated immunocytochemical expression of ICAM-1 in human renal carcinoma cells.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1993, Volume: 101, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, CD; Calcimycin; Carcinoma, Renal

1993
[Sulfolipids and glycolipid sulfotransferases in a human renal cell carcinoma cell line].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1992, Volume: 67, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Carcinoma, Renal Cell; Epidermal Growth Fa

1992
Modulation of vincristine sensitivity of human kidney tumor cells by pharmacological agents interfering with intracellular signals. No apparent relationship to changes in cytoplasmic Ca2+ or pH.
    Biochimica et biophysica acta, 1990, May-22, Volume: 1052, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Calcium; Colforsin; Cytoplasm; Humans

1990