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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Impotence

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Impotence in 2 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Research Excerpts

ExcerptRelevanceReference
"Treatment with fasudil normalized these molecular and histologic alterations, and restored erectile function."1.37Chronic treatment with an oral rho-kinase inhibitor restores erectile function by suppressing corporal apoptosis in diabetic rats. ( Kim, SW; Li, WJ; Paick, JS; Park, K, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, WJ1
Park, K1
Paick, JS1
Kim, SW1
Saito, M1
Ohmasa, F1
Dimitriadis, F1
Tsounapi, P1
Sejima, T1
Shimizu, S1
Kinoshita, Y1
Satoh, K1

Other Studies

2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Impotence

ArticleYear
Chronic treatment with an oral rho-kinase inhibitor restores erectile function by suppressing corporal apoptosis in diabetic rats.
    The journal of sexual medicine, 2011, Volume: 8, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Oral; Animals; Apoptosis; Blotting, W

2011
Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat.
    Pharmacological research, 2012, Volume: 66, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cyclic GMP; Erectile Dysfunction; Gene Expre

2012