Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
Page last updated: 2024-10-28

1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hypertension, Malignant

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Hypertension, Malignant in 1 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishikawa, Y1
Nishikimi, T1
Akimoto, K1
Ishimura, K1
Ono, H1
Matsuoka, H1

Other Studies

1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hypertension, Malignant

ArticleYear
Long-term administration of rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Desoxycorticosterone; Dinoprost; Dose-Respon

2006