Compounds > 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
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1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hyperparathyroidism

1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Hyperparathyroidism in 2 studies

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"In cell cultures prepared from human parathyroid adenomas, parathyroid hormone (PTH) mRNA expression decreased slowly."1.29Regulation of parathyroid hormone gene expression and peptide secretion in human parathyroid cells. ( Kahri, A; Liu, J; Teppo, AM; Voutilainen, R, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, J1
Kahri, A1
Teppo, AM1
Voutilainen, R1
Ridefelt, P1
Nygren, P1
Hellman, P1
Larsson, R1
Rastad, J1
Akerström, G1
Gylfe, E1

Other Studies

2 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hyperparathyroidism

ArticleYear
Regulation of parathyroid hormone gene expression and peptide secretion in human parathyroid cells.
    European journal of endocrinology, 1994, Volume: 130, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenoma; Alkaloids; Base Sequence; Blotting, Northern

1994
Regulation of parathyroid hormone release in normal and pathological parathyroid cells exposed to modulators of protein kinase C.
    Acta endocrinologica, 1992, Volume: 126, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenoma; Animals; Calcium; Cattle; Humans; Hypercalce

1992