1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Hyperparathyroidism, Secondary in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Hyperparathyroidism, Secondary: Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human parathyroid adenoma cells and bovine cells cultured for 1 day or exposed to a low concentration of a monoclonal antiparathyroid antibody exhibited right-shifted dependencies of PTH release and Ca2+i on extracellular Ca2+ and reduced Ca2+i transients." | 1.27 | Modulation of the Ca2+-sensing function of parathyroid cells in vitro and in hyperparathyroidism. ( Akerström, G; Gylfe, E; Johansson, H; Juhlin, C; Klareskoq, L; Larsson, R; Nygren, P; Rastad, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nygren, P | 1 |
| Gylfe, E | 1 |
| Larsson, R | 1 |
| Johansson, H | 1 |
| Juhlin, C | 1 |
| Klareskoq, L | 1 |
| Akerström, G | 1 |
| Rastad, J | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hyperparathyroidism, Secondary
| Article | Year |
|---|---|
Modulation of the Ca2+-sensing function of parathyroid cells in vitro and in hyperparathyroidism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenoma; Animals; Antibodies, Monoclonal; Calcium; Ca | 1988 |