1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Hyperoxia in 5 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was performed to determine the efficacy of ROCK inhibitor fasudil in blocking the development of hyperoxia-induced lung injury and fibrosis in neonatal rats." | 7.81 | Fasudil, an inhibitor of Rho-associated coiled-coil kinase, attenuates hyperoxia-induced pulmonary fibrosis in neonatal rats. ( Dang, HX; Fang, F; Li, J; Ning, W; Qi, XJ; Xu, F, 2015) |
| " This study was performed to determine the efficacy of ROCK inhibitor fasudil in blocking the development of hyperoxia-induced lung injury and fibrosis in neonatal rats." | 3.81 | Fasudil, an inhibitor of Rho-associated coiled-coil kinase, attenuates hyperoxia-induced pulmonary fibrosis in neonatal rats. ( Dang, HX; Fang, F; Li, J; Ning, W; Qi, XJ; Xu, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Chen, X | 1 |
| Qi, XJ | 1 |
| Ning, W | 1 |
| Xu, F | 1 |
| Dang, HX | 1 |
| Fang, F | 1 |
| Li, J | 1 |
| Ziino, AJ | 1 |
| Ivanovska, J | 1 |
| Belcastro, R | 1 |
| Kantores, C | 1 |
| Xu, EZ | 1 |
| Lau, M | 1 |
| McNamara, PJ | 1 |
| Tanswell, AK | 1 |
| Jankov, RP | 1 |
| de Frutos, S | 1 |
| Caldwell, E | 1 |
| Nitta, CH | 1 |
| Kanagy, NL | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Walker, MK | 1 |
| Gonzalez Bosc, LV | 1 |
| Suzuki, Y | 1 |
| Aoki, T | 1 |
| Takeuchi, O | 1 |
| Nishio, K | 1 |
| Suzuki, K | 1 |
| Miyata, A | 1 |
| Oyamada, Y | 1 |
| Takasugi, T | 1 |
| Mori, M | 1 |
| Fujita, H | 1 |
| Yamaguchi, K | 1 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Hyperoxia
| Article | Year |
|---|---|
Effects of a Rho kinase inhibitor on the sequential expression of ICAM-1, HIF-1α, Bcl-2 and caspase-3 in the retina of rats with oxygen-induced retinopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caspase 3; Disease Models, Animal; Gene Expr | 2013 |
Fasudil, an inhibitor of Rho-associated coiled-coil kinase, attenuates hyperoxia-induced pulmonary fibrosis in neonatal rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Blotting, Western; Disease | 2015 |
Effects of rho-kinase inhibition on pulmonary hypertension, lung growth, and structure in neonatal rats chronically exposed to hypoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Airway Remodeling; Amides; Animals; Animals, Newborn; | 2010 |
NFATc3 contributes to intermittent hypoxia-induced arterial remodeling in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aorta, Thoracic; Bosentan; Dioxoles; | 2010 |
Effect of hyperoxia on adhesion molecule expression in human endothelial cells and neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adh | 1997 |