1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Granulocytic Leukemia, Chronic in 5 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burthem, J | 1 |
| Rees-Unwin, K | 1 |
| Mottram, R | 1 |
| Adams, J | 1 |
| Lucas, GS | 1 |
| Spooncer, E | 1 |
| Whetton, AD | 1 |
| Motyl, T | 1 |
| Kasterka, M | 1 |
| Grzelkowska, K | 1 |
| Blachowski, S | 1 |
| Sysa, P | 1 |
| Ezawa, H | 1 |
| Harigaya, K | 1 |
| Ishii, G | 1 |
| Nakajima, N | 1 |
| Mikata, A | 1 |
| Huang, CC | 1 |
| Chang, CB | 1 |
| Liu, JY | 1 |
| Basavappa, S | 1 |
| Lim, PH | 1 |
| Takemura, Y | 1 |
| Koide, Y | 1 |
| Miyachi, H | 1 |
| Shibata, T | 1 |
| Sekiguchi, S | 1 |
| Tukemura, Y | 1 |
5 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Antigens, CD34; Benzamides; Cell Proliferatio | 2007 |
TGF-beta 1 inhibits polyamine biosynthesis in K 562 leukemic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosylmethionine Decarboxylase; Apoptosis; Cell Div | 1993 |
12-O-tetradecanoylphorbol-13-acetate (TPA) downregulates expression of CD30 in erythroleukemia cell line K562.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Blast Crisis; Cycloheximide; Dact | 1997 |
Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Calcium; Calcium Channel Blocke | 2001 |
Effect of verapamil on the class I major histocompatibility complex antigen expression in K562 chronic myelogenous leukemia cells treated with recombinant human interferon-gamma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Blotting, Northern; Calcimyci | 1992 |