1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Germinoblastoma in 6 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiloride was also found to inhibit the prolactin stimulation of DNA, RNA and protein synthesis, thus suggesting that the initial regulation of the Na+/H+ antiporter may initiate these responses as well as the mitogenic effect of prolactin." | 1.28 | Studies on the mechanism by which prolactin regulates protein, RNA, and DNA synthesis in Nb2 node lymphoma cells. ( Linebaugh, BE; Rillema, JA; Tarrant, TM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, S | 1 |
| Zhang, Y | 1 |
| Wang, Y | 1 |
| Lui, Y | 1 |
| Wei, W | 1 |
| Huang, X | 1 |
| Mao, W | 1 |
| Zuo, Y | 1 |
| Sarrabayrouse, G | 1 |
| Synaeve, C | 1 |
| Leveque, K | 1 |
| Favre, G | 1 |
| Tilkin-Mariamé, AF | 1 |
| Herbert, JM | 1 |
| Augereau, JM | 1 |
| Gleye, J | 1 |
| Maffrand, JP | 1 |
| Rillema, JA | 2 |
| Tarrant, TM | 2 |
| Linebaugh, BE | 1 |
| Waters, SB | 1 |
| Kelleher, D | 1 |
| Pandol, SJ | 1 |
| Kagnoff, MF | 1 |
6 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Germinoblastoma
| Article | Year |
|---|---|
Targeting P2X₇ receptor inhibits the metastasis of murine P388D1 lymphoid neoplasm cells to lymph nodes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line, Tumor; Lymph Nodes; Lymphatic Met | 2010 |
Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Amino Acid Chloromethyl Keto | 2007 |
Chelerythrine is a potent and specific inhibitor of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibiotics, Antineoplastic; Benz | 1990 |
Studies on the mechanism by which prolactin regulates protein, RNA, and DNA synthesis in Nb2 node lymphoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Carrier Proteins; Cell Division; DNA, Neop | 1989 |
Studies on the possible role of protein kinase C in the prolactin regulation of cell replication in Nb2 node lymphoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Cell Line; Gossypol; Isoquino | 1989 |
Phorbol myristate acetate induces IL-2 secretion by HUT 78 cells by a mechanism independent of protein kinase C translocation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line; Humans; Interleukin-2; Isoquinolines; Lymp | 1988 |