1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Esophagitis in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously showed that lower esophageal spincter (LES) tone depends on spontaneous production of inositol 1,4,5-trisphosphate (IP3) and release of intracellular Ca2+ and that acute experimental esophagitis reduces LES tone and IP3 production, suggesting damage to mechanisms responsible for release of Ca2+ from intracellular stores." | 3.69 | Experimental esophagitis affects intracellular calcium stores in the cat lower esophageal sphincter. ( Behar, J; Biancani, P; Kim, N; Rich, H; Sohn, UD, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rich, H | 1 |
| Sohn, UD | 1 |
| Behar, J | 1 |
| Kim, N | 1 |
| Biancani, P | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Esophagitis
| Article | Year |
|---|---|
Experimental esophagitis affects intracellular calcium stores in the cat lower esophageal sphincter.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Analysis of Variance; Animals; Benzimi | 1997 |