1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Endometriosis in 1 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Endometriosis: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the use of fasudil, a selective ROCK inhibitor, for the medical treatment of endometriosis-associated fibrosis, the effects of this agent on the cell proliferation, apoptosis, cell cycle, morphology, cell density, and contractility of ECSC were investigated." | 7.77 | Fasudil inhibits the proliferation and contractility and induces cell cycle arrest and apoptosis of human endometriotic stromal cells: a promising agent for the treatment of endometriosis. ( Abe, W; Kawano, Y; Li, H; Narahara, H; Nasu, K; Tsuno, A; Yuge, A, 2011) |
| "To assess the use of fasudil, a selective ROCK inhibitor, for the medical treatment of endometriosis-associated fibrosis, the effects of this agent on the cell proliferation, apoptosis, cell cycle, morphology, cell density, and contractility of ECSC were investigated." | 3.77 | Fasudil inhibits the proliferation and contractility and induces cell cycle arrest and apoptosis of human endometriotic stromal cells: a promising agent for the treatment of endometriosis. ( Abe, W; Kawano, Y; Li, H; Narahara, H; Nasu, K; Tsuno, A; Yuge, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuno, A | 1 |
| Nasu, K | 1 |
| Kawano, Y | 1 |
| Yuge, A | 1 |
| Li, H | 1 |
| Abe, W | 1 |
| Narahara, H | 1 |
1 other study available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Endometriosis
| Article | Year |
|---|---|
Fasudil inhibits the proliferation and contractility and induces cell cycle arrest and apoptosis of human endometriotic stromal cells: a promising agent for the treatment of endometriosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Apoptosis; Cell Cycle; Cell Proliferation; End | 2011 |